Search

Your search keyword '"Richard W. Truman"' showing total 2 results
Start Over Author "Richard W. Truman" Publisher centers for disease control and prevention
2 results on '"Richard W. Truman"'

1. Zoonotic Leprosy in the Southeastern United States

Author

Rahul Sharma, Pushpendra Singh, W.J. Loughry, J. Mitchell Lockhart, W. Barry Inman, Malcolm S. Duthie, Maria T. Pena, Luis A. Marcos, David M. Scollard, Stewart T. Cole, and Richard W. Truman

Subjects
leprosy, zoonotic leprosy, Hansen’s disease, Mycobacterium leprae, bacteria, armadillos, Medicine, Infectious and parasitic diseases, RC109-216
Abstract

Nine-banded armadillos (Dasypus novemcinctus) are naturally infected with Mycobacterium leprae and have been implicated in zoonotic transmission of leprosy. Early studies found this disease mainly in Texas and Louisiana, but armadillos in the southeastern United States appeared to be free of infection. We screened 645 armadillos from 8 locations in the southeastern United States not known to harbor enzootic leprosy for M. leprae DNA and antibodies. We found M. leprae–infected armadillos at each location, and 106 (16.4%) animals had serologic/PCR evidence of infection. Using single-nucleotide polymorphism variable number tandem repeat genotyping/genome sequencing, we detected M. leprae genotype 3I-2-v1 among 35 armadillos. Seven armadillos harbored a newly identified genotype (3I-2-v15). In comparison, 52 human patients from the same region were infected with 31 M. leprae types. However, 42.3% (22/52) of patients were infected with 1 of the 2 M. leprae genotype strains associated with armadillos. The geographic range and complexity of zoonotic leprosy is expanding.

Published
2015
Full Text
View/download PDF

2. Zoonotic Leprosy in the Southeastern United States

Author

David M. Scollard, J. Mitchell Lockhart, Maria T. Pena, Pushpendra Singh, Rahul Sharma, Stewart T. Cole, W. Barry Inman, W. J. Loughry, Malcolm S. Duthie, Richard W. Truman, and Luis A. Marcos

Subjects
Microbiology (medical), Veterinary medicine, Disease reservoir, animal structures, zoonotic leprosy, genotype, nine-banded armadillo, lcsh:Medicine, Serology, lcsh:Infectious and parasitic diseases, Zoonotic Leprosy in the Southeastern United States, Genotype, medicine, Dasypus novemcinctus, Animals, Humans, lcsh:RC109-216, bacteria, Mycobacterium leprae, Disease Reservoirs, biology, southeastern United States, integumentary system, Research, lcsh:R, biomarkers, biology.organism_classification, medicine.disease, Louisiana, Virology, Texas, zoonoses, Hansen’s disease, Variable number tandem repeat, Infectious Diseases, armadillos, embryonic structures, Enzootic, epidemiology, Leprosy, Hansen disease, leprosy
Abstract

The geographic range and complexity of this disease are increasing., Nine-banded armadillos (Dasypus novemcinctus) are naturally infected with Mycobacterium leprae and have been implicated in zoonotic transmission of leprosy. Early studies found this disease mainly in Texas and Louisiana, but armadillos in the southeastern United States appeared to be free of infection. We screened 645 armadillos from 8 locations in the southeastern United States not known to harbor enzootic leprosy for M. leprae DNA and antibodies. We found M. leprae–infected armadillos at each location, and 106 (16.4%) animals had serologic/PCR evidence of infection. Using single-nucleotide polymorphism variable number tandem repeat genotyping/genome sequencing, we detected M. leprae genotype 3I-2-v1 among 35 armadillos. Seven armadillos harbored a newly identified genotype (3I-2-v15). In comparison, 52 human patients from the same region were infected with 31 M. leprae types. However, 42.3% (22/52) of patients were infected with 1 of the 2 M. leprae genotype strains associated with armadillos. The geographic range and complexity of zoonotic leprosy is expanding.

Published
2015

Catalog

Books, media, physical & digital resources
See catalog results