1. Antigenic Variation of Avian Influenza A(H5N6) Viruses, Guangdong Province, China, 2014–2018
- Author
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Bai, Ru, Sikkema, Reina S., Li, Cong rong, Munnink, Bas B. Oude, Wu, Jie, Zou, Lirong, Jing, Yi, Lu, Jing, Yuan, Runyu, Liao, Ming, Koopmans, Marion P.G., Ke, Chang-wen, and Virology
- Subjects
Microbiology (medical) ,China ,animal structures ,Epidemiology ,Guangdong Province ,live poultry markets ,lcsh:Medicine ,Real-Time Polymerase Chain Reaction ,lcsh:Infectious and parasitic diseases ,03 medical and health sciences ,Antigenic Variation of Avian Influenza A(H5N6) Viruses, Guangdong Province, China, 2014–2018 ,Animals ,viruses ,lcsh:RC109-216 ,Antigens, Viral ,Phylogeny ,Poultry Diseases ,030304 developmental biology ,0303 health sciences ,Reverse Transcriptase Polymerase Chain Reaction ,030306 microbiology ,poultry ,Genetic Drift ,lcsh:R ,Dispatch ,food and beverages ,virus diseases ,zoonosis ,H5N6 ,zoonoses ,3. Good health ,Infectious Diseases ,Influenza A virus ,Influenza in Birds ,chickens ,avian influenza ,Antigenic variation - Abstract
Market surveillance showed continuing circulation of avian influenza A(H5N6) virus in live poultry markets in Guangdong Province in 2017, despite compulsory vaccination for avian influenza A(H5Nx) and A(H7N9). We analyzed H5N6 viruses from 2014-2018 from Guangdong Province, revealing antigenic drift and decreased antibody response against the vaccine strain in vaccinated chickens.
- Published
- 2019