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The 1st trimester of pregnancy is accompanied with changes in different biochemical and hematological parameters. Analyses scheduled to be performed in the 1st trimester are complete blood count, blood group, Rh factor and the double test. Many experts also suggest the determination of lipid status parameters as a routine analysis in the early pregnancy. Reliable data about maternal and fetal health can be obtained by the assessment of the above-mentioned parameters. They may be helpful in assessing the risk for pregnancy complication development and/or perinatal adverse outcomes. Prvi trimestar trudnoće praćen je promenama različitih biohemijskih i hematoloških parametara. Analize koje se rade u 1. trimestru su kompletna krvna slika, krvna grupa, Rh faktor i tzv. „double“ test. Mnogi stručnjaci predlažu određivanje parametara lipidnog statusa kao rutinsku analizu u ranoj trudnoći. Procenom gore navedenih parametara mogu se dobiti pouzdani podaci o zdravlju majke i fetusa, a mogu da posluže i za procenu rizika za razvoj komplikacija u trudnoći i/ili perinatalnih neželjenih ishoda.