1. Soluble ST2 and Diuretic Efficiency in Acute Heart Failure and Concomitant Renal Dysfunction
- Author
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Espriella R, Bayes-Genis A, Revuelta-LoPEZ E, Minana G, Santas E, Llacer P, Garcia-Blas S, Fernandez-Cisnal A, Bonanad C, Ventura S, Sanchez R, Bodi V, Cordero A, Facila L, Mollar A, Sanchis J, Nunez J, and IMPROVE-HF Investigators
- Subjects
sST2 ,Diuretic efficiency ,Congestion ,Acute heart failure ,Renal dysfunction ,Acute heart failure, Congestion, Diuretic efficiency, Renal dysfunction, sST2 - Abstract
BACKGROUND: Identifying patients at risk of poor diuretic response in acute heart failure (AHF) is critical to make prompt adjustments in therapy. The objective of this study was to investigate whether the circulating levels of soluble ST2 predict the cumulative diuretic efficiency (DE) at 24 and 72 hours in patients with AHF and concomitant renal dysfunction. METHODS AND RESULTS: This is a post hoc analysis of the IMPROVE-HF trial, in which we enrolled 160 patients with AHF and renal dysfunction (estimated glomerular filtrate rate of
- Published
- 2021