1. Supplementation with flax oil and vitamin C improves the outcome of Attention Deficit Hyperactivity Disorder (ADHD).
- Author
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Joshi K, Lad S, Kale M, Patwardhan B, Mahadik SP, Patni B, Chaudhary A, Bhave S, and Pandit A
- Subjects
- Ascorbic Acid pharmacology, Attention Deficit Disorder with Hyperactivity blood, Attention Deficit Disorder with Hyperactivity diagnosis, Child, Drug Therapy, Combination, Erythrocytes chemistry, Erythrocytes drug effects, Fatty Acids, Essential pharmacology, Fatty Acids, Essential therapeutic use, Fatty Acids, Unsaturated blood, Female, Humans, Linseed Oil pharmacology, Male, Pilot Projects, Thiobarbituric Acid Reactive Substances analysis, Treatment Outcome, Vitamins pharmacology, Vitamins therapeutic use, alpha-Linolenic Acid pharmacology, alpha-Linolenic Acid therapeutic use, Ascorbic Acid therapeutic use, Attention Deficit Disorder with Hyperactivity drug therapy, Dietary Supplements, Linseed Oil therapeutic use
- Abstract
Considerable clinical and experimental evidence now supports the idea that deficiencies or imbalances in certain highly unsaturated fatty acids may contribute to a range of common developmental disorders including Attention Deficit Hyperactivity Disorder (ADHD). Few intervention studies with LCPUFA supplementation have reported inconsistent and marginal results. This pilot study evaluates the effect of alpha linolenic acid (ALA)-rich nutritional supplementation in the form of flax oil and antioxidant emulsion on blood fatty acids composition and behavior in children with ADHD. Post-supplementation levels of RBC membrane fatty acids were significantly higher than pretreatment levels as well as the levels in control. There was significant improvement in the symptoms of ADHD reflected by reduction in total hyperactivity scores of ADHD children derived from ADHD rating scale.
- Published
- 2006
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