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Your search keyword '"Cameron, Mark J."' showing total 11 results
Start Over Author "Cameron, Mark J." Publisher cold spring harbor laboratory
11 results on '"Cameron, Mark J."'

1. Pre-vaccination transcriptomic profiles of immune responders to the MUC1 peptide vaccine for colon cancer prevention

Author

Cameron, Cheryl M, primary, Raghu, Vineet, additional, Richardson, Brian, additional, Zagore, Leah L, additional, Tamilselvan, Banumathi, additional, Golden, Jackelyn, additional, Cartwright, Michael, additional, Schoen, Robert E, additional, Finn, Olivera J, additional, Benos, Panayiotis V., additional, and Cameron, Mark J, additional

Published
2024
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2. Activated NK Cells with Pro-inflammatory Features are Associated with Atherogenesis in Perinatally HIV-Acquired Adolescents

Author

Alles, Mario, primary, Gunasena, Manuja, additional, Kettelhut, Aaren, additional, Ailstock, Kate, additional, Musiime, Victor, additional, Kityo, Cissy, additional, Richardson, Brian, additional, Mulhern, Will, additional, Tamilselvan, Banumathi, additional, Rubsamen, Michael, additional, Kasturiratna, Dhanuja, additional, Demberg, Thorsten, additional, Cameron, Cheryl M., additional, Cameron, Mark J., additional, Dirajlal-Fargo, Sahera, additional, Funderburg, Nicholas T., additional, and Liyanage, Namal P.M., additional

Published
2023
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3. Sex-specific niche signaling contributes to sexual dimorphism following stem cell transplantation

Author

Smith, Julianne N.P., primary, Cordova, Brittany A, additional, Richardson, Brian, additional, Christo, Kelsey F, additional, Campanelli, Jordan, additional, Broncano, Alyssia V, additional, Chen, Jonathan, additional, Lee, Juyeun, additional, Cameron, Scott J, additional, Lathia, Justin D, additional, Goodman, Wendy A, additional, Cameron, Mark J, additional, and Desai, Amar B, additional

Published
2022
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4. Significantly elevated antibody levels and neutralization titers in nursing home residents after SARS-CoV-2 BNT162b2 mRNA booster vaccination

Author

Canaday, David H., primary, Oyebanji, Oladayo A., additional, White, Elizabeth, additional, Keresztesy, Debbie, additional, Payne, Michael, additional, Wilk, Dennis, additional, Carias, Lenore, additional, Aung, Htin, additional, Denis, Kerri St., additional, Sheehan, Maegan L., additional, Berry, Sarah D., additional, Cameron, Cheryl M., additional, Cameron, Mark J., additional, Wilson, Brigid M., additional, Balazs, Alejandro B., additional, King, Christopher L., additional, and Gravenstein, Stefan, additional

Published
2021
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5. Significant reduction in humoral immunity among healthcare workers and nursing home residents 6 months after COVID-19 BNT162b2 mRNA vaccination

Author

Canaday, David H., primary, Oyebanji, Oladayo A., additional, Keresztesy, Debbie, additional, Payne, Michael, additional, Wilk, Dennis, additional, Carias, Lenore, additional, Aung, Htin, additional, Denis, Kerri St., additional, Lam, Evan C., additional, Rowley, Christopher F., additional, Berry, Sarah D., additional, Cameron, Cheryl M., additional, Cameron, Mark J., additional, Wilson, Brigid, additional, Balazs, Alejandro B., additional, King, Christopher L., additional, and Gravenstein, Stefan, additional

Published
2021
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6. Reduced BNT162b2 mRNA vaccine response in SARS-CoV-2-naive nursing home residents

Author

Canaday, David H., primary, Carias, Lenore, additional, Oyebanji, Oladayo A., additional, Keresztesy, Debbie, additional, Wilk, Dennis, additional, Payne, Michael, additional, Aung, Htin, additional, Denis, Kerri St., additional, Lam, Evan C., additional, Wilson, Brigid, additional, Rowley, Christopher F., additional, Berry, Sarah D., additional, Cameron, Cheryl M., additional, Cameron, Mark J., additional, Balazs, Alejandro B., additional, Gravenstein, Stefan, additional, and King, Christopher L., additional

Published
2021
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7. Male sex and age biases viral burden, viral shedding, and type 1 and 2 interferon responses during SARS-CoV-2 infection in ferrets

Author

Francis, Magen E., primary, Richardson, Brian, additional, McNeil, Mara, additional, Rioux, Melissa, additional, Foley, Mary K., additional, Ge, Anni, additional, Pechous, Roger D., additional, Kindrachuk, Jason, additional, Cameron, Cheryl M., additional, Richardson, Christopher, additional, Lew, Jocelyne, additional, Cameron, Mark J., additional, Gerdts, Volker, additional, Falzarano, Darryl, additional, and Kelvin, Alyson A., additional

Published
2021
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9. Oral tenofovir disoproxil fumarate/emtricitabine for HIV pre-exposure prophylaxis increases expression of type I/III interferon-stimulated factors in the gastrointestinal tract but not in the blood

Author

Hughes, Sean M., Levy, Claire N., Calienes, Fernanda, Stekler, Joanne D., Pandey, Urvashi, Vojtech, Lucia, Berard, Alicia R., Birse, Kenzie, Noel-Romas, Laura, Richardson, Brian, Golden, Jackelyn B., Cartwright, Michael, Collier, Ann C., Stevens, Claire E., Curlin, Marcel E., Holtz, Timothy H., Mugo, Nelly, Irungu, Elizabeth, Katabira, Elly, Muwonge, Timothy, Lama, Javier R., Baeten, Jared M., Burgener, Adam, Lingappa, Jairam R., McElrath, M. Juliana, Mackelprang, Romel, McGowan, Ian, Cranston, Ross D., Cameron, Mark J., and Hladik, Florian

Subjects
virus diseases
Abstract

Tenofovir disoproxil fumarate and emtricitabine are used for HIV treatment and pre-exposure prophylaxis. Previously, we found that topical rectal application of tenofovir 1% gel caused many gene expression changes. Here, we measured RNA and protein expression in several clinical trials of oral administration in HIV-uninfected individuals (using microarrays, RNAseq, droplet digital PCR, mass spectrometry, and microscopy). We found tens to hundreds of differentially expressed genes in the gastrointestinal tract, but none in the blood or female reproductive tract. In rectal samples from one trial, most of the 13 upregulated genes were related to type I/III interferon signaling. Similar changes were seen at the protein level in the same trial and in the duodenum and rectum in another trial. We conclude that tenofovir disoproxil fumarate and emtricitabine have little effect on gene expression in the blood or female reproductive tract but increase type I/III interferon signaling in the gut. This effect may enhance their anti-viral efficacy when used as pre-exposure prophylaxis, in particular to prevent rectal HIV transmission. However, it may also contribute to chronic immune activation and HIV reservoir maintenance in chronically treated people living with HIV.

Published
2019
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10. Treatment with commonly used antiretroviral drugs induces a type I/III interferon signature in the gut in the absence of HIV infection

Author

Hughes, Sean M., primary, Levy, Claire N., additional, Calienes, Fernanda L., additional, Stekler, Joanne D., additional, Pandey, Urvashi, additional, Vojtech, Lucia, additional, Berard, Alicia R., additional, Birse, Kenzie, additional, Noël-Romas, Laura, additional, Richardson, Brian, additional, Golden, Jackelyn B., additional, Cartwright, Michael, additional, Collier, Ann C., additional, Stevens, Claire E., additional, Curlin, Marcel E., additional, Holtz, Timothy H., additional, Mugo, Nelly, additional, Irungu, Elizabeth, additional, Katabira, Elly, additional, Muwonge, Timothy, additional, Lama, Javier R., additional, Baeten, Jared M., additional, Burgener, Adam, additional, Lingappa, Jairam R., additional, McElrath, M. Juliana, additional, Mackelprang, Romel, additional, McGowan, Ian, additional, Cranston, Ross D., additional, Cameron, Mark J., additional, and Hladik, Florian, additional

Published
2019
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11. Mucosal effects of tenofovir 1% gel

Author

Hladik, Florian, primary, Burgener, Adam, additional, Ballweber, Lamar, additional, Gottardo, Raphael, additional, Fourati, Slim, additional, Dai, James Y, additional, Cameron, Mark J, additional, Vojtech, Lucia, additional, Strobl, Johanna, additional, Hughes, Sean M, additional, Hoesley, Craig, additional, Andrew, Philip, additional, Johnson, Sherri, additional, Piper, Jeanna, additional, Friend, David R, additional, Ball, T Blake, additional, Cranston, Ross D., additional, Mayer, Kenneth H, additional, McElrath, M Juliana, additional, and McGowan, Ian, additional

Published
2014
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