Author: "Guest, Johnathan D." / Publisher: cold spring harbor laboratory - Searchworks@Jio Institute Digital Library Search Results

Your search keyword '"Guest, Johnathan D."' showing total 5 results

Start Over Author "Guest, Johnathan D." Publisher cold spring harbor laboratory

Author: Wu, Daichao, primary, Kolesnikov, Alexander, additional, Yin, Rui, additional, Guest, Johnathan D., additional, Gowthaman, Ragul, additional, Shmelev, Anton, additional, Serdyuk, Yana, additional, Efimov, Grigory A., additional, Pierce, Brian G., additional, and Mariuzza, Roy A., additional
Published: 2021
Full Text: View/download PDF

Author: Gowthaman, Ragul, Guest, Johnathan D, Yin, Rui, and Pierce, Brian G
Subjects: viruses
Abstract: Coronaviruses represent a major global threat as emerging pathogens, most recently SARS-CoV-2, the etiologic agent behind COVID-19, which is currently causing a global pandemic. The urgent need for effective vaccines and therapies is leading to a rapid rise in the number of high resolution structures of SARS-CoV-2 proteins that collectively reveal critical targets on the virus and a map of vulnerabilities. To enable structure-based design of vaccines and therapeutics, as well as insights into structural and molecular features of coronaviruses, we have developed the CoV3D database, which provides a view of SARS-CoV-2 and other coronavirus protein structures, updated on a weekly basis. This database includes and annotates structures of coronavirus proteins and their complexes with antibodies, receptors, and small molecules. Additionally, CoV3D provides information on spike glycoprotein sequence variability and polymorphisms, mapping these features onto the spike structure, and includes spike structures with modeled glycosylation. CoV3D is available at: https://cov3d.ibbr.umd.edu.
Published: 2020
Full Text: View/download PDF

Author: Yin, Rui, primary, Guest, Johnathan D., additional, Taherzadeh, Ghazaleh, additional, Gowthaman, Ragul, additional, Mittra, Ipsa, additional, Quackenbush, Jane, additional, and Pierce, Brian G., additional
Published: 2021
Full Text: View/download PDF

Author: Gowthaman, Ragul, primary, Guest, Johnathan D., additional, Yin, Rui, additional, Adolf-Bryfogle, Jared, additional, Schief, William R., additional, and Pierce, Brian G., additional
Published: 2020
Full Text: View/download PDF

Author: Pierce, Brian G., primary, Keck, Zhen-Yong, additional, Wang, Ruixue, additional, Lau, Patrick, additional, Garagusi, Kyle, additional, Elkholy, Khadija, additional, Toth, Eric A., additional, Urbanowicz, Richard A., additional, Guest, Johnathan D., additional, Agnihotri, Pragati, additional, Kerzic, Melissa C., additional, Marin, Alexander, additional, Andrianov, Alexander K., additional, Ball, Jonathan K., additional, Mariuzza, Roy A., additional, Fuerst, Thomas R., additional, and Foung, Steven K.H., additional
Published: 2020
Full Text: View/download PDF

Books, media, physical & digital resources

Searchworks