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Your search keyword '"Zheng Hongkun"' showing total 9 results
Start Over Author "Zheng Hongkun" Publisher cold spring harbor laboratory
9 results on '"Zheng Hongkun"'

1. Chinese fir genome and the evolution of gymnosperms

Author

Lin, Si-Zu, primary, Chen, Yu, additional, Wu, Chao, additional, Sun, Wei-Hong, additional, Li, Zhen, additional, Chen, Hengchi, additional, Wang, Jieyu, additional, Ji, Changmian, additional, Li, Shu-Bin, additional, Wang, Zhiwen, additional, Tsai, Wen-Chieh, additional, Ma, Xiang-Qing, additional, Lan, Si-Ren, additional, Zhang, Fei-Ping, additional, Xie, Ya-Cong, additional, Yao, Lei, additional, Zhang, Yan, additional, Lü, Meng-Meng, additional, Zhang, Jia-Jun, additional, Zhang, Di-Yang, additional, Ye, Yi-Quan, additional, Yu, Xia, additional, Xu, Shan-Shan, additional, Ma, Zhi-Hui, additional, Ding, Guo-Chang, additional, Cao, Guang-Qiu, additional, He, Zong-Ming, additional, Wu, Peng-Fei, additional, Lin, Kai-Min, additional, Liu, Ai-Qin, additional, Lin, Yan-Qing, additional, Ruan, Shao-Ning, additional, Liu, Bao, additional, Cao, Shi-Jiang, additional, Zhou, Li-Li, additional, Li, Ming, additional, Shuai, Peng, additional, Hou, Xiao-Long, additional, Wu, Yi-Han, additional, Li, Nuo, additional, Xiong, Sheng, additional, Hao, Yang, additional, Zhou, Zhuang, additional, Liu, Xue-Die, additional, Zuo, Dan-Dan, additional, Li, Jia, additional, Wang, Pei, additional, Zhang, Jian, additional, Liu, Ding-Kun, additional, Chen, Gui-Zhen, additional, Huang, Jie, additional, Huang, Ming-Zhong, additional, Li, Yuanyuan, additional, Zheng, Qinyao, additional, Zhao, Xiang, additional, Zhong, Wen-Ying, additional, Wang, Feng-Ling, additional, Cheng, Xin-Chao, additional, Yu, Yin, additional, Liu, Zhi-Wei, additional, Zheng, Hongkun, additional, Ming, Ray, additional, Van de Peer, Yves, additional, and Liu, Zhong-Jian, additional

Published
2022
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2. Golden pompano genome resource enables discovery of valuable gene determining growth traits

Author

Luo, Honglin, primary, Zhang, Yongde, additional, Ji, Changmian, additional, Zhao, Yongzhen, additional, Peng, Jinxia, additional, Xu, Yuhui, additional, Chen, Xiuli, additional, Huang, Yin, additional, Liu, Qingyun, additional, He, Pingping, additional, Feng, Pengfei, additional, Yang, Chunling, additional, Wei, Pinyuan, additional, Yu, Haiyan, additional, Zheng, Hongkun, additional, Lin, Yong, additional, and Chen, Xiaohan, additional

Published
2021
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4. Comparative genomics reveals evolutionary drivers of sessile life and left-right shell asymmetry in bivalves

Author

Zhang, Yang, primary, Mao, Fan, additional, Xiao, Shu, additional, Yu, Haiyan, additional, Xiang, Zhiming, additional, Xu, Fei, additional, Li, Jun, additional, Wang, Lili, additional, Xiong, Yuanyan, additional, Chen, Mengqiu, additional, Bao, Yongbo, additional, Deng, Yuewen, additional, Huo, Quan, additional, Zhang, Lvping, additional, Liu, Wenguang, additional, Li, Xuming, additional, Ma, Haitao, additional, Zhang, Yuehuan, additional, Mu, Xiyu, additional, Liu, Min, additional, Zheng, Hongkun, additional, Wong, Nai-Kei, additional, and Yu, Ziniu, additional

Published
2021
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5. Discovery of novel functions of minor ZGA gene on heart and vascular regulation in Golden pompano genome provides clues for anti-cancer therapeutic strategies

Author

luo, Honglin, Zhang, Yongde, Ji, Changmian, Zhao, Yongzhen, Peng, Jinxia, Chen, Xiuli, Li, Lequn, Huang, Yin, Liu, Qingyun, He, Pingping, Feng, Pengfei, Yang, Chunling, Wei, Pinyuan, Yu, Haiyan, Zheng, Hongkun, Lin, Yong, and Chen, Xiaohan

Abstract

The development of heart- and vascular-network is essential for embryonic survival and organ function. However, whether the genes in the minor zygotic genome activation (ZGA) shaped by a biased-subgenome affect the ZGA and have functions on heart and vascular development are largely unknown. In this study, we discover a novel gene nxh from a group of hub-genes within minor ZGA shaped by a WGD-driven-subgenome of the de novo golden pompano genome. We find that loss of its homolog nxhl in zebrafish not only delays the ZGA activation, but causes pericardial oedema, caudal fin defects, and impairs the growth of intersegmental vessel and caudal vein plexus. Furthermore, loss of nxhl reduces the heart- and vascular-associated landmark gene network (including keystone gene ptprb, hand2, tie2, hey2 , and s1pr1 , etc.) via a hitherto unreported nxhl -nucleolin- ptprb pathway. We also find that Harbi1 expression in cancer tissue is significantly higher than para-cancer tissue, and silencing of Harbi1, the human homolog of nxh , suppress the angiogenesis of the HUVECs, and migration and EMT of hepatocellular carcinoma cells, indicating its potential as an anti-cancer therapeutic target. Our findings provide new insights into cardio- and vascular-linked functions of the genes in the WGD shaping minor ZGA during marine fish embryo development and clues for anti-cancer therapeutic strategies.

Published
2019
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6. The subgenomes show asymmetric expression of alleles in hybrid lineages of Megalobrama amblycephala × Culter alburnus

Author

Ren, Li, primary, Li, Wuhui, additional, Qin, Qinbo, additional, Dai, He, additional, Han, Fengming, additional, Xiao, Jun, additional, Gao, Xin, additional, Cui, Jialin, additional, Wu, Chang, additional, Yan, Xiaojing, additional, Wang, Guoliang, additional, Liu, Guiming, additional, Liu, Jia, additional, Li, Jiaming, additional, Wan, Zhong, additional, Yang, Conghui, additional, Zhang, Chun, additional, Tao, Min, additional, Wang, Jing, additional, Luo, Kaikun, additional, Wang, Shi, additional, Hu, Fangzhou, additional, Zhao, Rurong, additional, Li, Xuming, additional, Liu, Min, additional, Zheng, Hongkun, additional, Zhou, Rong, additional, Shu, Yuqin, additional, Wang, Yude, additional, Liu, Qinfeng, additional, Tang, Chenchen, additional, Duan, Wei, additional, and Liu, Shaojun, additional

Published
2019
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7. Whole Genome and Embryo Transcriptome Analysis of Vertebrate IdentifiesnxhlControlling Angiogenesis by Targeting VE-PTP

Author

Luo, Honglin, primary, Zhang, Yongde, additional, Ji, Changmian, additional, Zhao, Yongzhen, additional, Peng, Jinxia, additional, Chen, Xiuli, additional, Huang, Yin, additional, Liu, Qingyun, additional, He, Pingping, additional, Feng, Pengfei, additional, Yang, Chunling, additional, Wei, Pinyuan, additional, Yu, Haiyan, additional, Zheng, Hongkun, additional, Lin, Yong, additional, and Chen, Xiaohan, additional

Published
2019
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8. The pomegranate (Punica granatum L.) genome provides insights into fruit quality and ovule developmental biology

Author

Yuan, Zhaohe, primary, Fang, Yanming, additional, Zhang, Taikui, additional, Fei, Zhangjun, additional, Han, Fengming, additional, Liu, Cuiyu, additional, Liu, Min, additional, Xiao, Wei, additional, Zhang, Wenjing, additional, Zhang, Mengwei, additional, Ju, Youhui, additional, Xu, Huili, additional, Dai, He, additional, Liu, Yujun, additional, Chen, Yanhui, additional, Wang, Lili, additional, Zhou, Jianqing, additional, Guan, Dian, additional, Yan, Ming, additional, Xia, Yanhua, additional, Huang, Xianbin, additional, Liu, Dongyuan, additional, Wei, Hongmin, additional, and Zheng, Hongkun, additional

Published
2017
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9. Origin and evolution of new exons in rodents

Author

Wang, Wen, primary, Zheng, Hongkun, additional, Yang, Shuang, additional, Yu, Haijing, additional, Li, Jun, additional, Jiang, Huifeng, additional, Su, Jianning, additional, Yang, Lei, additional, Zhang, Jianguo, additional, McDermott, Jason, additional, Samudrala, Ram, additional, Wang, Jian, additional, Yang, Huanming, additional, Yu, Jun, additional, Kristiansen, Karsten, additional, Wong, Gane Ka-Shu, additional, and Wang, Jun, additional

Published
2005
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