1. Relationship between Lymph Node Metastasis and a Low 18F-FDG PET/CT Axillary SUVmax Value in Breast Cancer
- Author
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Oktay Irkorucu, Ozgur Kulahci, Zeynel Abidin Tas, and Emel Kocyigit Deveci
- Subjects
medicine.medical_specialty ,Turkey ,Proliferation index ,Breast Neoplasms ,Metastasis ,Breast cancer ,Fluorodeoxyglucose F18 ,Positron Emission Tomography Computed Tomography ,medicine ,Humans ,skin and connective tissue diseases ,Retrospective Studies ,medicine.diagnostic_test ,Receiver operating characteristic ,business.industry ,Cancer ,General Medicine ,medicine.disease ,Axilla ,medicine.anatomical_structure ,Positron emission tomography ,Lymphatic Metastasis ,Positron-Emission Tomography ,Female ,Lymph Nodes ,Radiology ,Radiopharmaceuticals ,business ,Breast carcinoma - Abstract
OBJECTIVE To evaluate breast cancer patients with low F18-fluorodeoxy-glucose positron emission tomography/computed tomography scan (FPET) of axilla standardised maximum uptake value (SUVmax) along with their histopathological findings regarding axillary lymph node metastasis (LNM). STUDY DESIGN A descriptive study. Place and Duration of the Study: Adana City Education and Research Hospital, Turkey, from January 2015 to October 2018. METHODOLOGY The current study analysed the findings of 113 patients according to age, histopathological axillary LNM, estrogen and progesterone receptor status, tumour size, histological grade, Ki-67, HER2 and preoperative FPET SUVmax findings. Histopathological and immunohistochemical comparisons were made between FPET axilla SUVmax and univariate and multivariate parameters in breast carcinoma in terms of LNM. RESULTS The authors analysed the receiver operator characteristic curve for the FPET axilla SUVmax and set the cut-off value to 1.84 to predict LNM. However, it was also found that the SUVmax detected metastases in the axilla at values lower than 1.84. In the multivariate analysis, a statistically significant relationship was found between axilla LNM cases that have FPET axilla SUVmax less than 1.84, a Ki-67 index greater than 15% and tumour size greater than 2 cm (p
- Published
- 2021
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