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Objective: To identify, in a practical context, the knowledge of primary health care nurses about caring for people being treated for drug-resistant tuberculosis. Methods: This is a qualitative research, carried out with 26 primary health care nurses from the Southern Health District of the city of Manaus, Amazonas. Data collection took place from November to December 2022, through focus groups and individual interviews. Data were organized and processed using the Atlas.ti 8 software, and analyzed using Bardin's content analysis technique. Results: The participants showed insufficient knowledge about nursing care for people being treated for drug-resistant tuberculosis in primary care, as they verbalized in their speeches that they did not know what care they should perform, how to monitor and guide the directly observed treatment of these people. Conclusion: Insufficient knowledge and the need for continuing education of nursing professionals on care for people with drug-resistant tuberculosis in primary care were evident, with a view to exercising their roles in diagnosis, prevention, and guidance with directly observed treatment. [ABSTRACT FROM AUTHOR]

Objective: To analyze occurrences of drug-related adverse effects in treatment of tuberculosis and its association with clinical variables and outcome. Method: Cross-sectional study with 63 cases of tuberculosis treated at Tuberculosis and Leprosy Outpatient Clinic of São José do Rio Preto, São Paulo, from 2010 to 2015. We used frequency analysis and chi-square test with Monte Carlo correction. Results: Adverse effects started before the third month of treatment; effects were more frequent, with predominance of gastric irritation. There was association between medical conduct and adverse effects (p=0.009). Conclusion: Adverse effects caused by medications may impair the clinical outcome due to risk of treatment withdrawal. Health professionals should be alert to signs and symptoms related to adverse effects, implementing the necessary behaviors to neutralize or reduce complaints, aiming adherence to treatment and cure of the disease. [ABSTRACT FROM AUTHOR]