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Our explorative work aimed to qualitatively analyze the factors affecting human security and psychological well-being in a group of migrants temporarily hosted in a Nigerian transit center. The study involved 250 migrants from different Western and sub-Saharan African countries who were interviewed during their stay in International Organization for Migration – supported transit centers. Thematic content analysis was performed on the texts of the interviews. Motivations for departure from the home country, resources available for migrants’ sense of security, expectations for their future, experience in the host country, and the relationship between human insecurity and life satisfaction were the main emerging themes.