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Introduction. Status epilepticus (SE) is a medical emergency and requires rapid treatment. Incidence of SE is 10-41 per 100 000 population. [1] There are no data about incidence, principles of treatment and outcome of status epilepticus in Latvia, so this study was made to collect information at Pauls Stradiņš Clinical University Hospital. Aim. To analyse clinical profile, diagnostics, therapy and outcome of status epilepticus patients stationed at Pauls Stradiņš Clinical University Hospital from 2012 to 2016. Methods. In this retrospective study all status epilepticus patients stationed in Pauls Stradiņš Clinical University Hospital from 2012 to 2016 were selected. Patient medical records were analysed and information about previous history of seizures, type of seizure, duration of hospitalization, electroencephalogram (EEG) results, therapy, complications and outcome of therapy was collected. Collected data were compared to evidence-based guidelines. Results. In the study 44 patients with status epilepticus were found. The most of the seizures were focal and only some were generalized, but in some cases medical records had no information about the seizure. The electroencephalogram was made for more than a half of the patients and served as the basis for the diagnosis of non-concurrent status epilepticus. Almost all patients received first line and second line treatment. Third line treatment was given in 73% of cases. Half of the patients developed treatment-related complications during hospitalization, the most common complication was intrahospital infection. Intrahospital mortality was 11%, all the other patients were discharged or transferred to another hospital. [ABSTRACT FROM AUTHOR]