1. Sarcoidosis with myelitis and autonomic neuropathy treated with infliximab.
- Author
-
Zeeman VA and Stenø CPM
- Subjects
- Male, Humans, Middle Aged, Infliximab therapeutic use, Prednisolone therapeutic use, Magnetic Resonance Imaging, Central Nervous System Diseases diagnosis, Sarcoidosis diagnosis, Myelitis
- Abstract
In this case report, a 55-year-old man presented with back pain, urinary retention, sensory disturbances, erectile dysfunction, leg paresis and orthostatism. Spinal MRI showed longitudinal extensive myelitis. Lymph node biopsy was compatible with sarcoidosis and a diagnosis of probable neurosarcoidosis (NS) was made. The patient benefited from prednisolone but relapsed during withdrawal. Infliximab resulted in almost complete remission. In conclusion, relapse is often seen when phasing out prednisolone, whereas infliximab appears to have a lasting effect and should be considered in the early stages of severe NS., (Published under Open Access CC-BY-NC-BD 4.0. https://creativecommons.org/licenses/by-nc-nd/4.0/.)
- Published
- 2023