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There is no information on the use of herbal medicines as substitute for benzodiazepine hypnotics in electroconvulsive therapy. A 50-year-old woman was admitted to our department due to worsening depressive symptoms. To perform electroconvulsive therapy, we reduced the dose of the benzodiazepine hypnotic flunitrazepam and initiated 7.5 g of sansoninto, followed by the discontinuation of flunitrazepam. A remission of symptoms was observed after 5 sessions of electroconvulsive therapy, which yielded effective convulsions. Since it is often difficult to reduce or discontinue benzodiazepine hypnotics, sansoninto can be considered an alternative insomnia treatment when electroconvulsive therapy is performed.