1. Non-eosinophilic asthma: current perspectives
- Author
-
Esteban-Gorgojo I, Antolín-Amérigo D, Domínguez-Ortega J, and Quirce S
- Subjects
Asthma ,non-eosinophilic asthma ,asthma phenotype ,asthma endotype ,neutrophilic asthma ,Immunologic diseases. Allergy ,RC581-607 - Abstract
Ignacio Esteban-Gorgojo,1 Darío Antolín-Amérigo,2 Javier Domínguez-Ortega,3,4 Santiago Quirce3,4 1Department of Allergy, Hospital General de Villalba, Madrid, Spain; 2Department of Allergy, Hospital Universitario Ramón y Cajal (IRYCIS), Madrid, Spain; 3Department of Allergy, Hospital La Paz Institute for Health Research (IdiPAZ), 4CIBER de Enfermedades Respiratorias, CIBERES, Madrid, Spain Abstract: Although non-eosinophilic asthma (NEA) is not the best known and most prevalent asthma phenotype, its importance cannot be underestimated. NEA is characterized by airway inflammation with the absence of eosinophils, subsequent to activation of non-predominant type 2 immunologic pathways. This phenotype, which possibly includes several not well-defined subphenotypes, is defined by an eosinophil count
- Published
- 2018