1. Exploration of the Risk Factors of Anemia in Patients with Tuberculous Meningitis in South China.
- Author
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Wen, An, Leng, Er-Ling, Cao, Wen-Feng, Xiang, Zheng-bing, Rao, Wei, Cai, Wen, Zhou, Yong-Liang, Hu, Fan, Wu, Ling-feng, Zhang, Ping, and Liu, Shi-Min
- Subjects
TUBERCULOUS meningitis ,DISEASE risk factors ,LOGISTIC regression analysis ,ELECTRONIC health records ,DEMOGRAPHIC characteristics - Abstract
aimed to describe in detail the prevalence of anemia in patients with TBM in Southern China and its association with the clinical forms of TB, as well as other characteristics of these patients. Methods: We conducted a retrospective analysis of patients diagnosed with TBM at two tertiary hospitals in southern China. The demographic characteristics, clinical characteristics, and laboratory results of 114 patients with TBM were collected. Multivariate logistic regression analysis was performed to explore the risk factors for anemia in patients with TBM. Results: Electronic medical record data of adult patients diagnosed with TBM from January 2004 to December 2019 were reviewed. Among 134 patients with TBM, 20 were excluded and 114 were analyzed, of whom 33 had anemic, the prevalence rate of anemia was 28.9%. Among patients with anemia, 51.5% had hypochromic microcytic anemia, 33.3% had normochromic normocytic anemia, and 15.2% had macrocytic anemia. Fever duration, TBM grade III and ESR were found to be independent predictors of anemia. Conclusion: Anemia was highly prevalent in patients with TBM, mainly hypochromic microcytic anemia. Besides, Fever duration, TBM grade III and ESR are predictors of anemia in patients with TBM. [ABSTRACT FROM AUTHOR]
- Published
- 2023
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