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This study evaluates the role of spokespersons and message control in complex organizations facing ambiguous crises. Specifically, the Centers for Disease Control and Prevention's (CDC) response to the anthrax crisis in 2001 is offered as a case study. A textual analysis of CDC telebriefings and corresponding print media coverage of the anthrax crisis reveals the use of multiple spokespersons and poor message control resulted in a seemingly fragmented CDC message and apparent loss of CDC credibility. The study concludes that limiting the number of spokespersons and appropriate use of strategic ambiguity may afford organizations an opportunity to make sense of the situation, avoid confusing and contradictory messages and protect organizational credibility. Recommendations include (1) limiting the number of spokespersons, which allows for greater message control while reducing contradictory and inconsistent messages, (2) maintaining an organizational willingness to revise publicly stated positions as more accurate information becomes available, and (3) actively using strategic ambiguity as a mechanism to protect organizational credibility. [ABSTRACT FROM AUTHOR]