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Objective To investigate the efficacy of LVIS stent-assisted Target coil embolization in the treatment of very small intracranial aneurysms. Methods A retrospective analysis was performed for the clinical data and follow-up results of 47 patients with very small intracranial aneurysms who underwent LVIS stent-assisted Target coil embolization in our center from July 2015 to May 2023. Results For the 47 patients, angiography immediately after surgery showed dense embolization in 32 patients (68.1%), residual aneurysm neck in 11 patients (23.4%), and partial embolization in 4 patients (8.5%). Perioperative complication was observed in 4 patients (8.5%), among whom 2 had intraoperative bleeding due to ruptured aneurysms (1 died and 1 had no obvious sequela after dense embolization), 1 had intracranial infection after ruptured aneurysm surgery (with no neurolo-gical deficit after anti-infective therapy), and 1 had thrombosis during surgery (with no neurological deficit after the intraoperative application of tirofiban). Radiological follow-up examination was performed for 33 patients, among whom 29 (87.9%) achieved complete embolization of aneurysms and 4 (12.1%) had stable aneurysms. During follow-up, 1 patient died due to temporal lobe hemorrhage after 14 days of discharge, while the other patients did not experience rebleeding. Conclusion LVIS stent-assisted Target coil embolization is safe and effective in the treatment of very small intracranial aneurysms, and therefore, it holds promise for clinical application.