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1. Mycobacterium tuberculosis pneumonia and bacteremia after allogeneic hematopoietic stem cell transplant: report of an instructive pediatric case.

Author

Biral E, Faraci M, Lanino E, Morreale G, Giardino S, Moroni C, Losurdo G, Magnano GM, Senno E, and Castagnola E

Subjects
Antibiotics, Antitubercular therapeutic use, Bacteremia pathology, Child, Humans, Male, Mycobacterium tuberculosis isolation & purification, Pneumonia, Bacterial drug therapy, Pneumonia, Bacterial pathology, Thorax diagnostic imaging, Thorax microbiology, Thorax pathology, Tomography, X-Ray Computed methods, Transplantation, Homologous, Treatment Outcome, Tuberculosis drug therapy, Tuberculosis pathology, Ultrasonography, Bacteremia microbiology, Hematopoietic Stem Cell Transplantation, Mycobacterium tuberculosis pathogenicity, Pneumonia, Bacterial microbiology, Tuberculosis microbiology
Abstract

Pulmonary infections often complicate hematopoietic stem cell transplantation (HSCT) outcome. Uncommon aetiologies, like Mycobacterium tuberculosis, should be considered when the clinical conditions do not fully improve with standard antimicrobial therapy and microbiological evaluations are repeatedly negative for bacteria and fungi. We describe an interesting pediatric case of miliary lung tuberculosis after HSCT, which was successfully treated after administering the appropriate therapy.

Published
2012

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