1. Neutrophil dysfunction in prepubertal periodontitis associated with Papillon-Lefèvre syndrome.
- Author
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D'Angelo M, Margiotta V, Franco V, and Agate V
- Subjects
- Aggressive Periodontitis etiology, Chemotaxis, Leukocyte, Child, Preschool, Female, Humans, Immunohistochemistry, Immunologic Tests, Monocytes metabolism, Monocytes ultrastructure, Neutrophils ultrastructure, Papillon-Lefevre Disease etiology, Aggressive Periodontitis diagnosis, Neutrophils metabolism, Papillon-Lefevre Disease diagnosis
- Abstract
Although prepubertal periodontitis (PP) is often associated with the Papillon-Lefèvre (PLS), the etiopathogenetic mechanism in this disease has not been clarified as yet. A three and half year old female with leukocyte chemotaxis deficiency and decrease of T-lymphocytes is presented. The immunohistochemical evaluation of neutrophils showed a reduction of myeloperoxidase content, whereas ultrastructural studies revealed no particular change. The possible role of such a deficiency in the pathogenesis of the periodontal lesion is discussed.
- Published
- 1992