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Steering knuckle connects steering system, suspension system and braking system to the chassis. The steering knuckle contributes a significant weight to the total weight of a vehicle. Increasing the efficiency of an automobile without compromising the performances is the major challenge faced by the manufacturers. This paper presents an effective topology optimization of steering knuckle used in a vehicle with the primary objective of minimizing weight. The study on optimization of knuckle is divided into two phases, the first phase involves making of a computer-aided design model of the original steering knuckle and carry out finite element analysis on the knuckle by estimating the loads, which are acting on the component. In the second phase, design optimization of the model of steering knuckle is carried out, and excess material is removed at the region where induced stress is negligible as obtained in finite element analysis assuming standard boundary and loading conditions. The paper describes a research work carried out to optimize structural topology giving the essential details. The methodology may be applied to optimize structural components used in applications where the ratio of desired properties to the cost, generally in terms of weight, is to be optimized. In the case of automobiles, strength to weight ratio has to be maximized. New researchers working in the area will have an understanding of the procedures, and further, the techniques may be applied to design in general. [ABSTRACT FROM AUTHOR]