1. Segregation of Flowing Blood: Mathematical Description
- Author
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A Tokarev, Grigory Panasenko, Fazoil I. Ataullakhanov, Institut Camille Jordan [Villeurbanne] (ICJ), École Centrale de Lyon (ECL), Université de Lyon-Université de Lyon-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université Jean Monnet [Saint-Étienne] (UJM)-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Centre National de la Recherche Scientifique (CNRS), National Research Center for Haematology [Moscow], and Ministry of Health and Social Development of Russian Federation [Moscow]
- Subjects
Blood clotting ,Applied Mathematics ,0206 medical engineering ,02 engineering and technology ,Radial distribution ,Blood flow ,Biology ,020601 biomedical engineering ,01 natural sciences ,010305 fluids & plasmas ,Rheology ,Modeling and Simulation ,0103 physical sciences ,Immunology ,Biophysics ,[MATH.MATH-AP]Mathematics [math]/Analysis of PDEs [math.AP] ,Platelet ,Blood corpuscles ,ComputingMilieux_MISCELLANEOUS ,circulatory and respiratory physiology - Abstract
Blood rheology is completely determined by its major corpuscles which are erythro- cytes, or red blood cells (RBCs). That is why understanding and correct mathematical description of RBCs behavior in blood is a critical step in modelling the blood dynamics. Various phenom- ena provided by RBCs such as aggregation, deformation, shear-induced diffusion and non-uniform radial distribution affect the passage of blood through the vessels. Hence, they have to be taken into account while modelling the blood dynamics. Other important blood corpuscles are platelets, which are crucial for blood clotting. RBCs strongly affect the platelet transport in blood expelling them to the vessel walls and increasing their dispersion, which has to be considered in models of clotting. In this article we give a brief review of basic modern approaches in mathematical descrip- tion of these phenomena, discuss their applicability to real flow conditions and propose further pathways for developing the theory of blood flow.
- Published
- 2011
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