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In order to verify the effect of the new fully biodegradable external dressing on the repair of diabetes skin wounds and the promotion of wound healing, this study applied sodium alginate hydrogel dressing products which are supplemented with phage and conotoxin analgesic peptides to the skin lesions of diabetes mice, and comprehensively used the quantitative measurement of serological indicators, Image J Tissue section and other techniques to evaluate the effect of the new hydrogel dressing on the repair of diabetes wounds and the promotion of wound healing. The behavioral observation and analysis of mice did not show obvious regularity and difference. According to the results of serum cytokine analysis, functional hydrogel dressings can promote cell regeneration and wound healing in mice. Image J software analysis showed that the healing results of the experimental group were better than those of the negative control group, and the percentage of collagen fiber content showed an upward trend. Through comprehensive evaluation, it can be observed that the new fully biodegradable external dressing has obvious positive effects on wound healing, collagen fiber reconstruction and wound infection prevention of diabetes. The new biodegradable dressing not only promotes wound healing but also solves environmental pollution problems. It meets the sustainable development needs of society and has broad application prospects.

In order to verify the effect of the new green and low-carbon hydrogel dressing on promoting wound healing, this project applied a sodium alginate hydrogel dressing product containing Escherichia coli and taro toxin analgesic polypeptide (The specific ingredients of the dressing) to skin wounds in common rats. Effects of the hydrogel dressing on promoting skin wound healing was evaluated by observing the occurrence and frequency of behavioral changes in rats, observing wwhistological sections under a high-power microscope, changes in serum cytokine indicators, and Image J analysis of collagen fiber reconstruction ratios in tissue sections. Through comprehensive evaluation, it can be found that hydrogel dressing has analgesic, anti-inflammatory and anti-infection effects on rat wound surface, and acts on promoting wound healing, promoting the formation of new blood vessels in the damaged skin tissue area, promoting the growth of granulation tissue, and promoting the reconstruction of collagen fibers in wound tissue.