1. Study of factors affecting Small for Size Syndrome Post-Adult living donor liver transplantation
- Author
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Mahmoud A Ameen, Walid Rafat Abdelaty, Mohamed Abdalla Salman, Nesrin Abd Allah, Ahmed Abdallah, Ahmed F.A. Youssef, Ahmed Abdallah Salman, Amany Sholkamy, Mahmoud Gouda Omar, Hossam El-Din Shaaban, Ossama Ramzy Youssef, and Ahmad Yahia Abdel Dayem
- Subjects
Male ,medicine.medical_specialty ,medicine.medical_treatment ,Portal venous pressure ,lcsh:Surgery ,Hemodynamics ,Liver transplantation ,03 medical and health sciences ,Graft size ,0302 clinical medicine ,Portal pressure ,Living Donors ,Humans ,Medicine ,Child ,Retrospective Studies ,Small for size syndrome ,business.industry ,Retrospective cohort study ,Organ Size ,Perioperative ,lcsh:RD1-811 ,Surgery ,Small-for-size syndrome ,Mean blood pressure ,030220 oncology & carcinogenesis ,030211 gastroenterology & hepatology ,business - Abstract
Abstarct: Aim: Recently, increasing evidence showed that small-for-size syndrome (SFSS) is a multifactorial disease which is precipitated by various perioperative factors other than graft size. We conducted the current work to evaluate perioperative effectors, which can increase the risk of SFSS following adult living-donor liver transplantation (LDLT). Methods: This is a retrospective study on 110 adult cirrhotic cases (mean age of 48.4 ± 6.9 years old) who underwent adult LDLT. Most cases were males (89%). Cases were categorized into two groups based on the occurrence of SFSS. The groups were compared regarding preoperative (gender, age, comorbidities, baseline investigations), intraoperative (mean blood pressure and glucose; mean operation time; number of packed red cells, plasma, platelets, and cryoprecipitate units; time of cold and warm ischemia, and anhepatic phase; preclamping and post-reperfusion portal pressures), and postoperative factors (relevant investigations, hospital stay). Results: Postoperatively, 23 patients developed SFSS (20.9%). SFSS group had significantly lower preoperative graft recipient weight ratio (GRWR) (0.76 ± 0.1% versus 1.03 ± 0.15, respectively; p
- Published
- 2021