4 results on '"Anca Maria Panaitescu"'
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2. Pineal Gland Disorders and Circadian Rhythm Alterations in Pregnancy and Lactation
- Author
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Anca Maria Panaitescu, Francesca Gabriela Paslaru, Corin Badiu, Gheorghe Peltecu, Diana Maria Chitimus, Suzana Elena Voiculescu, and Ana-Maria Zagrean
- Subjects
Pregnancy ,Fetus ,business.industry ,Physiology ,medicine.disease ,Preeclampsia ,Miscarriage ,Melatonin ,Pineal gland ,Low birth weight ,medicine.anatomical_structure ,medicine ,Gestation ,medicine.symptom ,business ,reproductive and urinary physiology ,medicine.drug - Abstract
Pineal tumors are extremely rare during pregnancy and cause symptoms by compression or direct invasion. Surgery is recommended during the second trimester, and chemotherapy after 14 weeks of gestation. Pineal cysts don’t usually cause complications during pregnancy or labor. The hormonal imbalances generated by night-shift work schedules or jet lag conceivably contribute to the increased risk of preterm birth, low birth weight, and miscarriage in women who are exposed to a desynchronization of the sleep-wake cycle during pregnancy. Maternal chronodisruption and melatonin deficiency have been linked to peripartum depression. Serum levels of melatonin are significantly reduced in women with preeclampsia, in those bearing growth-restricted fetuses, and in women who spontaneously abort in early pregnancy. Melatonin is currently being tested in clinical trials to determine if its perceived antioxidant and free-radical scavenger effects reduced the incidence of preeclampsia, fetal growth restriction (FGR), and birth asphyxia.
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- 2020
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3. The Pineal Gland and its Function in Pregnancy and Lactation
- Author
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Anca Maria Panaitescu, Leon Zagrean, Ana-Maria Zagrean, Corin Badiu, Diana Maria Chitimus, and Gheorghe Peltecu
- Subjects
endocrine system ,medicine.medical_specialty ,Pregnancy ,Circadian clock ,Biology ,medicine.disease ,Melatonin ,Pineal gland ,medicine.anatomical_structure ,Endocrinology ,Oxytocin ,Internal medicine ,Placenta ,Lactation ,medicine ,Circadian rhythm ,reproductive and urinary physiology ,hormones, hormone substitutes, and hormone antagonists ,medicine.drug - Abstract
The pineal is a neuroendocrine gland and a circadian oscillator, producing and releasing melatonin during the night and modulating a broad spectrum of physiological functions, including the female reproductive function. The pineal undergoes morphological, structural, and biochemical changes in pregnancy. Melatonin carries a photoperiodic signal from the endogenous clock, and its secretion maintains a circadian rhythm during pregnancy and lactation, with gradual increases during gestation and labor, that returns postpartum to pregestational values. Melatonin crosses the placenta unaltered or is excreted in the breast milk, thus signaling photoperiodicity in the fetus or the breastfed infant, respectively. Placenta is also an important source for melatonin, within which it exerts autocrine and paracrine actions. During labor, melatonin may synergize with oxytocin, promoting uterine contractility. Melatonin has a protective effect during pregnancy through its free-radical scavenging and antioxidant capacities, intervening to balance the oxidative challenge that accompanies the high metabolic demands during pregnancy, labor, and lactation.
- Published
- 2020
- Full Text
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4. Contributors
- Author
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Sonir R. Antonini, Zain Awamleh, Sioban Bacon, Corin Badiu, Kathryn Beardsall, Ingrid J. Block-Kurbisch, Kristien Boelaert, Isabelle Bourdeau, Marcello D. Bronstein, Helen Budge, Manuela Cerbone, Marlene Chakhtoura, Pranesh Chakraborty, Diana Maria Chitimus, Gertrude Costin, Mehul T. Dattani, Diva D. De Leon, Cheri L. Deal, Johnny Deladoëy, Lois E. Donovan, Ghada El-Hajj Fuleihan, Denice S. Feig, Analía V. Freire, Qinqin Gao, Audrey Garneau, Andrea Glezer, Veronica Gomez-Lobo, Romina P. Grinspon, Victor Han, Russell C. Hovey, Raquel Soares Jallad, Venkata S. Jonnakuti, Aspasia Karalis, Harshini Katugampola, Asma Khalil, Md. Wasim Khan, Ahmed Khattab, Christopher S. Kovacs, T’ng Chang Kwok, Anne-Marie Laberge, André Lacroix, David C.W. Lau, Sarah Elizabeth Lawrence, Brian T. Layden, Diana Le Duc, Na Li, Xiang Li, Alexis Light, Bailin Liu, Xiyuan Lu, Eugenie R. Lumbers, Anne Macdonald, Marcio Carlos Machado, Elizabeth A. McGee, Sam A. Mesiano, Geetha Mukerji, Cathy M. Murray, Mithra L. Narasimhan, Maria New, Amanda L. Ogilvy-Stuart, Shalini Ojha, Christine J. Orr, Anca Maria Panaitescu, Georgios E. Papadakis, Francesca Gabriela Paslaru, Jonathan Paul, Gheorghe Peltecu, Jason Phung, Nelly Pitteloud, Jerilynn C. Prior, Zoe E. Quandt, Bethany Radford, Fernando S. Ramalho, Rodolfo A. Rey, María Gabriela Ropelato, Adrian Eugen Rosca, Christopher W. Rowe, Jessica A. Ryniec, Anna Sadovnikova, Kirsten E. Salmeen, Mark E. Samuels, Sahar Sherf, Jien Shim, Roger Smith, Diana E. Stanescu, Brett Stark, Monica F. Stecchini, Matthieu St-Jean, Jerome F. Strauss, Miao Sun, Michael E. Symonds, Jiaqi Tang, Rosemary Townsend, Suzana Elena Voiculescu, Julia Elisabeth von Oettingen, Leanne M. Ward, Declan Wayne, Catherine Takacs Witkop, John J. Wysolmerski, Cheng Xu, Zhice Xu, Jennifer M. Yamamoto, Jessica S. Yang, Steven L. Young, Run Yu, Ana-Maria Zagrean, Leon Zagrean, Mengshu Zhang, and Xiuwen Zhou
- Published
- 2020
- Full Text
- View/download PDF
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