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2 results on '"Charlotte Falaise"'

1. List of Contributors

Author

Zouher Amzil, Jean-Marie Bard, Michael A. Borowitzka, Nathalie Bourgougnon, Intan C. Dewi, Amandine M.N. Caruana, Yusuf Chisti, Laurence Coiffard, Céline Couteau, Aurélie Couzinet-Mossion, Justine Dumay, Charlotte Falaise, Joël Fleurence, Joe M. Fox, Taejun Han, Claire Hellio, Matthew L. Julius, Jang K. Kim, Ira A. Levine, Michael W. Lomas, Virginie Mimouni, Michèle Morançais, Jean-Luc Mouget, Hassan Nazih, Jihae Park, P.D. Rajakumar, Julianne P. Sexton, Lionel Ulmann, Gaëtane Wielgosz-Collin, Charles Yarish, and Paul V. Zimba

Published
2018
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2. Anticancer, Antiviral, Antibacterial, and Antifungal Properties in Microalgae

Author

Charlotte Falaise, Intan C. Dewi, Claire Hellio, Nathalie Bourgougnon, Jean-Luc Mouget, Le Mans Université (UM), Mer, molécules et santé EA 2160 (MMS), Université de Nantes - UFR des Sciences Pharmaceutiques et Biologiques, Université de Nantes (UN)-Université de Nantes (UN)-Le Mans Université (UM)-Université de Nantes - UFR des Sciences et des Techniques (UN UFR ST), Université de Nantes (UN)-Université de Nantes (UN), Institut Universitaire Européen de la Mer (IUEM), Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Brest (UBO)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Biotechnologie et Chimie Marines (LBCM), Université de Bretagne Sud (UBS)-Université de Brest (UBO)-Institut Universitaire Européen de la Mer (IUEM), Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Brest (UBO)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS), Ira A. Levine, and Joël Fleurence

Subjects
0106 biological sciences, 0301 basic medicine, Antifungal, Cyanobacteria, medicine.drug_class, [SDV]Life Sciences [q-bio], Microorganism, Antibiotics, 01 natural sciences, Bioactive compounds, 03 medical and health sciences, 010608 biotechnology, Microalgae, medicine, [SDV.BV]Life Sciences [q-bio]/Vegetal Biology, 14. Life underwater, Antiviral, biology, Chemistry, Aquatic ecosystem, Biological activity, biology.organism_classification, Antimicrobial, Antibacterial, Anticancer, 030104 developmental biology, Biochemistry, [SDE.BE]Environmental Sciences/Biodiversity and Ecology, Antibacterial activity
Abstract

International audience; Microalgae and cyanobacteria are photoautotrophic microorganisms, present in almost all ecosystems around the world. Due to their rich biodiversity and possibly high growth performances, microalgae are the basis of most aquatic ecosystems; however, they constitute a vast bioresource, underexplored and underexploited yet. Regarding health and disease prevention, microalgae and cyanobacteria have been recognized as potential sources of new natural antimicrobial substances. Indeed, these organisms produce a great variety of bioactive secondary metabolites, which are accumulated in the cell or excreted in the surrounding environments, usually at the end of the exponential and the stationary phase of growth. Many of these metabolites display antibacterial activity, such as free saturated or unsaturated fatty acids, and there is a research effort to find natural molecules to allow limiting the misuse of commercial antibiotics, because their prolonged use may result in the development of resistant bacterial strains. Other microalgal and cyanobacterial compounds present antiproliferative or antifungal properties, or are able to inhibit viral infection and/or replication. One major potential but promising commercial application of these substances is thus the area of pharmaceuticals, antibiotics, and other biologically active compounds.

Published
2018
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