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Your search keyword '"Doglietto, Giovanni (ORCID:0000-0002-7394-768X)"' showing total 6 results
Start Over Author "Doglietto, Giovanni (ORCID:0000-0002-7394-768X)" Publisher elsevier
6 results on '"Doglietto, Giovanni (ORCID:0000-0002-7394-768X)"'

1. Chilaiditi's syndrome

Author

Rosa, Fausto, Pacelli, Fabio, Tortorelli, Antonio Pio, Papa, Valerio, Bossola, Maurizio, Doglietto, Giovanni, Rosa, Fausto (ORCID:0000-0002-7280-8354), Pacelli, Fabio (ORCID:0000-0002-2013-6525), Papa, Valerio (ORCID:0000-0002-3709-8924), Bossola, Maurizio (ORCID:0000-0003-1627-0235), Doglietto, Giovanni (ORCID:0000-0002-7394-768X), Rosa, Fausto, Pacelli, Fabio, Tortorelli, Antonio Pio, Papa, Valerio, Bossola, Maurizio, Doglietto, Giovanni, Rosa, Fausto (ORCID:0000-0002-7280-8354), Pacelli, Fabio (ORCID:0000-0002-2013-6525), Papa, Valerio (ORCID:0000-0002-3709-8924), Bossola, Maurizio (ORCID:0000-0003-1627-0235), and Doglietto, Giovanni (ORCID:0000-0002-7394-768X)

Abstract

No abstract available

Published
2011

2. Outcomes of clinical t4m0 extra-peritoneal rectal cancer treated with preoperative radiochemotherapy and surgery: a prospective evaluation of a single institutional experience.

Author

Valentini, Vincenzo, Coco, Claudio, Rizzo, Gianluca, Manno, Alberto, Crucitti, Antonio, Mattana, Claudio, Ratto, Carlo, Verbo, Alessandro, Vecchio, Fabio Maria, Barbaro, Brunella, Gambacorta, Maria Antonietta, Montoro, Caterina, Barba, Maria Cristina, Sofo, Luigi, Papa, Valerio, Menghi, Roberta, D'Ugo, Domenico, Doglietto, Giovanni, Valentini, Vincenzo (ORCID:0000-0003-4637-6487), Coco, Claudio (ORCID:0000-0002-4713-7093), Crucitti, Antonio (ORCID:0000-0003-3496-4185), Mattana, Claudio (ORCID:0000-0002-8605-4952), Ratto, Carlo (ORCID:0000-0002-0556-0037), Verbo, Alessandro (ORCID:0000-0003-4993-6638), Vecchio, Fabio Maria (ORCID:0000-0002-9197-2264), Barbaro, Brunella (ORCID:0000-0002-9638-543X), Gambacorta, Maria Antonietta (ORCID:0000-0001-5455-8737), Sofo, Luigi (ORCID:0000-0002-0592-5999), Papa, Valerio (ORCID:0000-0002-3709-8924), D'Ugo, Domenico (ORCID:0000-0001-6657-6318), Doglietto, Giovanni (ORCID:0000-0002-7394-768X), Valentini, Vincenzo, Coco, Claudio, Rizzo, Gianluca, Manno, Alberto, Crucitti, Antonio, Mattana, Claudio, Ratto, Carlo, Verbo, Alessandro, Vecchio, Fabio Maria, Barbaro, Brunella, Gambacorta, Maria Antonietta, Montoro, Caterina, Barba, Maria Cristina, Sofo, Luigi, Papa, Valerio, Menghi, Roberta, D'Ugo, Domenico, Doglietto, Giovanni, Valentini, Vincenzo (ORCID:0000-0003-4637-6487), Coco, Claudio (ORCID:0000-0002-4713-7093), Crucitti, Antonio (ORCID:0000-0003-3496-4185), Mattana, Claudio (ORCID:0000-0002-8605-4952), Ratto, Carlo (ORCID:0000-0002-0556-0037), Verbo, Alessandro (ORCID:0000-0003-4993-6638), Vecchio, Fabio Maria (ORCID:0000-0002-9197-2264), Barbaro, Brunella (ORCID:0000-0002-9638-543X), Gambacorta, Maria Antonietta (ORCID:0000-0001-5455-8737), Sofo, Luigi (ORCID:0000-0002-0592-5999), Papa, Valerio (ORCID:0000-0002-3709-8924), D'Ugo, Domenico (ORCID:0000-0001-6657-6318), and Doglietto, Giovanni (ORCID:0000-0002-7394-768X)

Abstract

Our objective was evaluate the outcome of primary clinical T4M0 extraperitoneal rectal cancer treated by neoadjuvant radiochemotherapy. Prognosis of clinical T4 rectal cancer is poor. Preoperative chemoradiation therapy may be beneficial. The results obtained are unclear due to lack of objective and strictly applied staging methods. METHODS: Patients with primary, clinical, T4MO, extraperitoneal rectal cancer, defined by transrectal ultrasonography, computed tomography or magnetic resonance imaging, were considered. Intraoperative radiotherapy and adjuvant chemotherapy were employed in some patients after curative resection (R0). Variables influencing the possibility to perform an R0 resection and a sphincter-saving procedure were investigated as predictors of outcome. RESULTS: 100 patients were included. R0 resection was performed in 78 patients. R0 resection rate was greater in females (93% vs 67%) and in responders to neoadjuvant chemoradiation (94% vs 60%). The ability to perform a sphincter-saving procedure was 57%, greater in middle rectal location (85% vs 51%) and in responders to the chemoradiation (70% vs 47%). Median follow-up was 31 months (range, 4-136). Local recurrences were found in 7 patients (10%). Five-year local control in R0 patients was 90% and better in the IORT group (100%). Distant relapse occurred in 24 patients (30%). Five-year overall survival was 59%, and was better after an R0 versus an R1 or R2 resection (68% vs 22%). Overall and disease free survival in R0 patients improved after overall downstaging. Adjuvant chemotherapy given in addition to the neoadjuvant therapy did not appear to offer benefit in improving survival. CONCLUSION: A multimodal approach enabled us to obtain a 5-year overall survival of about 60%. IORT increased local control. The role of adjuvant chemotherapy needs to be further investigated

Published
2009

3. Outcomes of clinical T4M0 extra-peritoneal rectal cancer treated with preoperative radiochemtoherapy and surgery. A prospective evalation of a single institutional experience.

Author

Valentini, Vincenzo, Coco, Claudio, Rizzo, Gianluca, Manno, Alberto, Crucitti, Antonio, Mattana, Claudio, Ratto, Carlo, Verbo, Alessandro, Vecchio, Fabio Maria, Barbaro, Brunella, Gambacorta, Maria Antonietta, Montoro, Caterina, Barba, Maria Cristina, Sofo, Luigi, D'Ugo, Domenico, Doglietto, Giovanni, Valentini, Vincenzo (ORCID:0000-0003-4637-6487), Coco, Claudio (ORCID:0000-0002-4713-7093), Crucitti, Antonio (ORCID:0000-0003-3496-4185), Mattana, Claudio (ORCID:0000-0002-8605-4952), Ratto, Carlo (ORCID:0000-0002-0556-0037), Verbo, Alessandro (ORCID:0000-0003-4993-6638), Vecchio, Fabio Maria (ORCID:0000-0002-9197-2264), Barbaro, Brunella (ORCID:0000-0002-9638-543X), Gambacorta, Maria Antonietta (ORCID:0000-0001-5455-8737), Sofo, Luigi (ORCID:0000-0002-0592-5999), D'Ugo, Domenico (ORCID:0000-0001-6657-6318), Doglietto, Giovanni (ORCID:0000-0002-7394-768X), Valentini, Vincenzo, Coco, Claudio, Rizzo, Gianluca, Manno, Alberto, Crucitti, Antonio, Mattana, Claudio, Ratto, Carlo, Verbo, Alessandro, Vecchio, Fabio Maria, Barbaro, Brunella, Gambacorta, Maria Antonietta, Montoro, Caterina, Barba, Maria Cristina, Sofo, Luigi, D'Ugo, Domenico, Doglietto, Giovanni, Valentini, Vincenzo (ORCID:0000-0003-4637-6487), Coco, Claudio (ORCID:0000-0002-4713-7093), Crucitti, Antonio (ORCID:0000-0003-3496-4185), Mattana, Claudio (ORCID:0000-0002-8605-4952), Ratto, Carlo (ORCID:0000-0002-0556-0037), Verbo, Alessandro (ORCID:0000-0003-4993-6638), Vecchio, Fabio Maria (ORCID:0000-0002-9197-2264), Barbaro, Brunella (ORCID:0000-0002-9638-543X), Gambacorta, Maria Antonietta (ORCID:0000-0001-5455-8737), Sofo, Luigi (ORCID:0000-0002-0592-5999), D'Ugo, Domenico (ORCID:0000-0001-6657-6318), and Doglietto, Giovanni (ORCID:0000-0002-7394-768X)

Published
2009

4. Intra-operative radiotherapy (IORT) in pancreatic cancer: Joint analysis of the ISIORT-Europe experience.

Author

Valentini, Vincenzo, Doglietto, Giovanni, Mattiucci, Gian Carlo, Morganti, Alessio Giuseppe, D'Agostino, Giuseppe Roberto, Valentini, Vincenzo (ORCID:0000-0003-4637-6487), Doglietto, Giovanni (ORCID:0000-0002-7394-768X), Mattiucci, Gian Carlo (ORCID:0000-0001-6500-0413), Valentini, Vincenzo, Doglietto, Giovanni, Mattiucci, Gian Carlo, Morganti, Alessio Giuseppe, D'Agostino, Giuseppe Roberto, Valentini, Vincenzo (ORCID:0000-0003-4637-6487), Doglietto, Giovanni (ORCID:0000-0002-7394-768X), and Mattiucci, Gian Carlo (ORCID:0000-0001-6500-0413)

Published
2009

5. Taste Intensity and Hedonic Responses to Simple Beverages in Gastrointestinal Cancer Patients.

Author

Bossola, Maurizio, Cadoni, Gabriella, Bellantone, Rocco Domenico Alfonso, Carriero, Concetta, Carriero, Elena, Ottaviani, Fabrizio, Borzomati, Domenico, Tortorelli, Antonio Pio, Doglietto, Giovanni, Bossola, Maurizio (ORCID:0000-0003-1627-0235), Cadoni, Gabriella (ORCID:0000-0001-8244-784X), Bellantone, Rocco Domenico Alfonso (ORCID:0000-0002-0844-3469), Doglietto, Giovanni (ORCID:0000-0002-7394-768X), Bossola, Maurizio, Cadoni, Gabriella, Bellantone, Rocco Domenico Alfonso, Carriero, Concetta, Carriero, Elena, Ottaviani, Fabrizio, Borzomati, Domenico, Tortorelli, Antonio Pio, Doglietto, Giovanni, Bossola, Maurizio (ORCID:0000-0003-1627-0235), Cadoni, Gabriella (ORCID:0000-0001-8244-784X), Bellantone, Rocco Domenico Alfonso (ORCID:0000-0002-0844-3469), and Doglietto, Giovanni (ORCID:0000-0002-7394-768X)

Abstract

Changes in the taste of food have been implicated as a potential cause of reduced dietary intake among cancer patients. However, data on intensity and hedonic responses to the four basic tastes in cancer are scanty and contradictory. The present study aimed at evaluating taste intensity and hedonic responses to simple beverages in 47 anorectic patients affected by gastrointestinal cancer and in 55 healthy subjects. Five suprathreshold concentrations of each of the four test substances (sucrose in black current drinks, citric acid in the lemonade, NaCl in unsalted tomato juice, and urea in tonic water) were used. Patients were invited to express a judgment of intensity and pleasantness ranging from 0 to 10. Mean intensity scores directly correlated with concentrations of sour, salty, bitter, and sweet stimuli, in both normals and those with cancer. Intensity judgments were higher in cancer patients with respect to sweet (for median and high concentrations, P<0.05), salty (for all concentrations, P<0.05), and bitter tastes (for median concentration, P<0.01). Hedonic function increased with the increase of the stimuli only for the sweet taste. A negative linear correlation was found between sour, bitter, and salty concentrations and hedonic score. Both in cancer patients and in healthy subjects, hedonic judgments increased with the increase of the stimulus for the sweet taste (r=0.978 and r=0.985, P=0.004 and P=0.002, respectively), and decreased for the salty (r=-0.827 and r=-0.884, P=0.084 and P=0.047, respectively) and bitter tastes (r=-0.990 and r=-0.962, P=0.009 and P=0.001, respectively). For the sour taste, the hedonic scores remained stable with the increase of the stimulus in noncancer controls (r=-0.785, P=0.115) and decreased in cancer patients (r=-0.996, P=0.0001). The hedonic scores for the sweet taste and the bitter taste were similar in cancer patients and healthy subjects, and these scores were significantly higher in cancer patients than in he

Published
2007

6. -Double-balloon enteroscopy for diagnosis of a Meckel's diverticulum in a patient with GI bleeding of obscure origin

Author

Gasbarrini, Antonio, Di Caro, Simona, Mutignani, Massimiliano, Cammarota, Giovanni, Fini, Lucia, Pacelli, Fabio, Pola, Paolo, Doglietto, Giovanni, Costamagna, Guido, Gasbarrini, Giovanni Battista, Gasbarrini, Antonio (ORCID:0000-0002-7278-4823), Mutignani, Massimiliano (ORCID:0000-0002-1272-4888), Cammarota, Giovanni (ORCID:0000-0002-3626-6148), Pacelli, Fabio (ORCID:0000-0002-2013-6525), Doglietto, Giovanni (ORCID:0000-0002-7394-768X), Costamagna, Guido (ORCID:0000-0002-8100-2731), Gasbarrini, Antonio, Di Caro, Simona, Mutignani, Massimiliano, Cammarota, Giovanni, Fini, Lucia, Pacelli, Fabio, Pola, Paolo, Doglietto, Giovanni, Costamagna, Guido, Gasbarrini, Giovanni Battista, Gasbarrini, Antonio (ORCID:0000-0002-7278-4823), Mutignani, Massimiliano (ORCID:0000-0002-1272-4888), Cammarota, Giovanni (ORCID:0000-0002-3626-6148), Pacelli, Fabio (ORCID:0000-0002-2013-6525), Doglietto, Giovanni (ORCID:0000-0002-7394-768X), and Costamagna, Guido (ORCID:0000-0002-8100-2731)

Abstract

No abstract available

Published
2005

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