1. Metastatic meningioma: Case report of a WHO grade I meningioma with liver metastases and review of the literature
- Author
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Bryce D. Beutler, MD, Emilie T. Nguyen, MD, Rex A. Parker, MD, Clement Tran, MD, Jay Acharya, MD, Fernando A. Torres, MD, and Nageshwara Gullapalli, MD
- Subjects
Medical physics. Medical radiology. Nuclear medicine ,R895-920 - Abstract
Meningioma represents the most frequently diagnosed primary brain tumor, accounting for over one-third of central nervous system neoplasms. The majority of tumors are categorized as benign. However, albeit rarely, meningiomas may metastasize to distant sites. We describe a 78-year-old man with a history of recurrent World Health Organization grade I meningioma managed who presented for evaluation of weakness and urinary retention. A computed tomography scan obtained in the emergency department revealed multiple scattered low-density liver lesions. Subsequent magnetic resonance imaging showed a 5.5-centimeter heterogeneous enhancing mass with 2 smaller enhancing lesions suspicious for a primary or secondary malignant neoplasm. Microscopic examination of a tissue sample obtained via liver biopsy demonstrated a metastatic spindle cell neoplasm with histologic features compatible with a diagnosis of World Health Organization grade I transitional meningioma. The patient was referred to hematology/oncology for systemic therapy. Keywords: Meningioma, Meningioma staging, Metastatic meningioma, Liver metastases, Central nervous system neoplasms, WHO grade I meningioma
- Published
- 2020
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