1. Comparison of diffusion-weighted imaging and gadoxetic acid-enhanced MR images in the evaluation of hepatocellular carcinoma and hypovascular hepatocellular nodules.
- Author
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Di Pietropaolo M, Briani C, Federici GF, Marignani M, Begini P, Delle Fave G, and Iannicelli E
- Subjects
- Aged, Aged, 80 and over, Disease Progression, Female, Humans, Image Enhancement, Male, Middle Aged, Retrospective Studies, Carcinoma, Hepatocellular diagnosis, Contrast Media, Diffusion Magnetic Resonance Imaging, Gadolinium DTPA, Liver pathology, Liver Neoplasms diagnosis, Magnetic Resonance Imaging methods
- Abstract
Purpose: To compare diffusion-weighted imaging (DWI) and gadolinium ethoxybenzyl diethylenetriaminepentaacetic acid (Gd-EOB-DTPA) magnetic resonance imaging (MRI) in the evaluation of hepatocellular carcinoma (HCC) and nodules at high risk of HCC transformation., Materials and Methods: We evaluated nodules' size, vascular pattern, and signal intensity on hepatobiliary phase images and on DWI of 105 nodules (41 cirrhotic patients)., Results: A total of 35/66 HCCs identified on Gd-EOB-DTPA MRI showed hyperintensity on DWI. A total of 25/39 nodules (hypovascular and hypointense nodule on hepatobiliary phase images) progressed to HCC (higher risk for nodules ≥10mm in size and hyperintense on DWI, P<.05)., Conclusion: Gd-EOB-DTPA MRI demonstrated a significant role in the identification of nodule at higher risk of HCC transformation, and hyperintensity on DWI was associated with progression to HCC., (Copyright © 2015 Elsevier Inc. All rights reserved.)
- Published
- 2015
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