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9 results on '"Giancarlo Albo"'

1. Genomic Profiling of Hormone-Naïve Lymph Node Metastases in Patients with Prostate Cancer

Author

Pamela L. Paris, Matthias D. Hofer, Giancarlo Albo, Rainer Kuefer, Juergen E. Gschwend, Richard E. Hautmann, Jane Fridyland, Jeffrey Simko, Peter R. Carroll, Mark A. Rubin, and Colin Collins

Subjects
Lymph nodes, prostate cancer, aCGH, metastases, biomarkers, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

The progression of organ-confined prostate cancer to metastatic cancer is inevitably fatal. Consequently, identification of structural changes in the genome and associated transcriptional responses that drive this progression is critical to understanding the disease process and the development of biomarkers and therapeutic targets. In this study, whole genome copy number changes in genomes of hormone-naïve lymph node metastases were profiled using array comparative genomic hybridization, and matched primaries were included for a subset. Matched primaries and lymph node metastases showed very similar copy number profiles that are distinct from primary tumors that fail to metastasize.

Published
2006
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2. Holmium laser lithotripsy enhanced by Moses™ technology in percutaneous nephrolithotomy: preliminary results from a comparative study

Author

M. Fontana, E. Lievore, Stefano Paolo Zanetti, Fabrizio Longo, Emanuele Montanari, E. De Lorenzis, Luca Boeri, Giancarlo Albo, Andrea Gallioli, and M. Turetti

Subjects
business.industry, Urology, medicine.medical_treatment, Holmium laser, Medicine, Lithotripsy, business, Percutaneous nephrolithotomy, Nuclear medicine, lcsh:Diseases of the genitourinary system. Urology, lcsh:RC870-923, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, lcsh:RC254-282
Published
2020

3. Clinical comparison of mini-percutaneous nephrolithotomy with vacuum cleaner effect or with a vacuum-assisted access sheath: A single center experience

Author

M. Turetti, Giancarlo Albo, I. Fulgheri, E. De Lorenzis, F. Botticelli, Carolina Bebi, Andrea Gallioli, Stefano Paolo Zanetti, M. Fontana, Emanuele Montanari, Luca Boeri, Fabrizio Longo, and E. Lievore

Subjects
medicine.medical_specialty, business.product_category, Materials science, Vacuum assisted, Urology, Single Center, lcsh:Diseases of the genitourinary system. Urology, lcsh:RC870-923, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, lcsh:RC254-282, Surgery, medicine, Vacuum cleaner, business, Mini percutaneous nephrolithotomy
Published
2020

4. 10-Year microbiological scenario of uropathogens in a single tertiary centre and the distinctive features of the urology department

Author

Emanuele Montanari, Luca Boeri, E. De Lorenzis, Giancarlo Albo, Alessandra Bandera, Fabrizio Longo, Carolina Bebi, Lorenzo Rocchini, F. Ripa, and D. Mangioni

Subjects
medicine.medical_specialty, Urology department, business.industry, Urology, General surgery, Medicine, business, lcsh:Diseases of the genitourinary system. Urology, lcsh:RC870-923, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, lcsh:RC254-282
Published
2020

5. Extended pelvic lymphnode dissection during robotic prostatectomy: Antegrade and retrograde technique

Author

E. De Lorenzis, Stefano Paolo Zanetti, Franco Palmisano, F. Ripa, Emanuele Montanari, Lorenzo Rocchini, Luca Boeri, Andrea Gallioli, and Giancarlo Albo

Subjects
medicine.medical_specialty, business.industry, Urology, medicine, Dissection (medical), Robotic prostatectomy, medicine.disease, business, lcsh:Diseases of the genitourinary system. Urology, lcsh:RC870-923, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, lcsh:RC254-282, Surgery
Published
2020

6. Allium ureteral stents: A critical analysis of our cases

Author

Giancarlo Albo, E. De Lorenzis, Stefano Paolo Zanetti, Emanuele Montanari, M. Fontana, Luca Boeri, Fabrizio Longo, Lorenzo Rocchini, Andrea Gallioli, and Gianluca Sampogna

Subjects
medicine.medical_specialty, biology, business.industry, Urology, Ureteral stents, biology.organism_classification, lcsh:Diseases of the genitourinary system. Urology, lcsh:RC870-923, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, lcsh:RC254-282, Surgery, medicine, Allium, business
Published
2020

7. Renal pelvic pressure fluctuations during vacuum assisted mini-PCNL: May this technique help reducing infectious complications?

Author

Lorenzo Rocchini, Fabrizio Longo, Giancarlo Albo, E. Lievore, M. Turetti, E. De Lorenzis, Emanuele Montanari, Andrea Gallioli, M. Fontana, and Stefano Paolo Zanetti

Subjects
medicine.medical_specialty, business.industry, Vacuum assisted, Urology, Medicine, business, lcsh:Diseases of the genitourinary system. Urology, lcsh:RC870-923, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Renal pelvic, lcsh:RC254-282, Surgery
Published
2020

8. Safety of nephrostomy tube exchange performed without periprocedural antibiotic therapy in patients with asymptomatic bacteriuria: Preliminary results

Author

Michele Spinelli, Gianluca Sampogna, Giancarlo Albo, Emanuele Montanari, E. De Lorenzis, F. Ripa, Andrea Gallioli, Franco Palmisano, Fabrizio Longo, Stefano Paolo Zanetti, E. Lievore, and Lorenzo Rocchini

Subjects
medicine.medical_specialty, business.industry, Urology, Nephrostomy tube, lcsh:Diseases of the genitourinary system. Urology, lcsh:RC870-923, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, lcsh:RC254-282, Surgery, Antibiotic therapy, Medicine, In patient, business, Asymptomatic bacteriuria
Published
2020

9. Alterations of the serum peptidome in renal cell carcinoma discriminating benign and malignant kidney tumors

Author

Stefano Ferrero, Giancarlo Albo, Simone Nicolardi, Clizia Chinello, Marta Cazzaniga, Veronica Mainini, Stefano Signorini, Yuri E. M. van der Burgt, André M. Deelder, Salvatore S. Di Pierro, Valeria Squeo, Fulvio Magni, Erica Gianazza, Gianazza, E, Chinello, C, Mainini, V, Cazzaniga, M, Squeo, V, Albo, G, Signorini, S, Di Pierro, S, Ferrero, S, Nicolardi, S, van der Burgt, Y, Deelder, A, and Magni, F

Subjects
Adult, Male, Proteomics, Pathology, medicine.medical_specialty, renal cell carcinoma, Proteome, Biophysics, Biology, Biochemistry, Asymptomatic, Renal cell carcinoma, medicine, Carcinoma, Biomarkers, Tumor, Humans, Stage (cooking), Carcinoma, Renal Cell, proteomic, ClinProt, Aged, Aged, 80 and over, Kidney, Magnetic beads, Mass spectrometry, biological fluid, Middle Aged, Omics, medicine.disease, Kidney Neoplasms, Neoplasm Proteins, Gene Expression Regulation, Neoplastic, medicine.anatomical_structure, Biological fluids, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization, Immunology, biomarker, Female, medicine.symptom, SDPR, Peptides
Abstract

Renal cell carcinoma (RCC) is typically asymptomatic and surgery usually increases patient's life only for early stage tumors. However, some cystic and solid renal lesions cannot be confidently differentiated from clear-cell-RCC. Therefore possible markers for early detection and to distinguish malignant kidney tumors are needed. To this aim, we applied MALDI-TOF and LC-MS/MS analysis to RPC18 MB purified serum of ccRCC, non-ccRCC patients and controls. A cluster of five signals differentiate malignant tumors from benign renal masses and healthy subjects. Moreover, a combination of six ions showed the highest specificity and sensitivity to distinguish ccRCC from controls. Healthy subjects were also differentiated from non-ccRCC by three features. Peptide ratios obtained by MALDI-TOF were compared with those from label-free LC-ESI and no statistical difference was found (p>0.05). ESI-results were linked with MALDI profiles by both TOF/TOF sequencing and MALDI FT-ICR accurate mass measurements. About 200 unique endogenous peptides, originating from 32 proteins, were identified. Among them, SDPR and ZYX were found down-expressed, while SRGN and TMSL3 were up-expressed. In conclusion, our results suggest the possibility to discriminate malignant kidney tumors based on a cluster of serum peptides. Moreover, label-free approach may represent a valid method to verify results obtained by MALDI-TOF. This article is part of a Special Issue entitled: Integrated omics.

Published
2012

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