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10. Contributors

Author

Adam, Gaelen P., primary, Ancker, Jessica S., additional, Bates, David W., additional, Benson, Nicole M., additional, Boxwala, Aziz A., additional, Brown, Steven, additional, Cerrato, Paul, additional, Cimino, James J., additional, Cook, David A., additional, Cresswell, Kathrin, additional, Davis, Sharon E., additional, Del Fiol, Guilherme, additional, Desai, Apurva, additional, Eisenberg, Floyd, additional, Franklin, Amy, additional, Fraser, Hamish S.F., additional, Fry, Emory A., additional, Glaser, John, additional, Greenes, Robert A., additional, Halamka, John, additional, Haug, Peter, additional, Hongsermeier, Tonya, additional, Huff, Stanley M., additional, Jenders, Robert A., additional, Johnson, Darren K., additional, Kawamoto, Kensaku, additional, Konnyu, Kristin J., additional, Lau, Lee Min, additional, Lee, Preston, additional, Lenert, Leslie A., additional, Magrabi, Farah, additional, Matheny, Michael E., additional, Maviglia, Saverio M., additional, McGreevey III, John D., additional, Miksch, Timothy, additional, Nanjo, Claude, additional, Nemati, Shamim, additional, Ohno-Machado, Lucila, additional, Oniki, Thomas A., additional, Patel, Vimla L., additional, Peleg, Mor, additional, Rhodes, Bryn, additional, Rocha, Beatriz H., additional, Rocha, Roberto A., additional, Rodriguez, Jorge A., additional, Saldanha, Ian Jude, additional, Salmasian, Hojjat, additional, Samal, Lipika, additional, Schmid, Christopher H., additional, Schreiber, Richard, additional, Shellum, Jane, additional, Shortliffe, Edward H., additional, Sottara, Davide, additional, Trikalinos, Thomas A., additional, Turchioe, Meghan Reading, additional, Williams, Marc S., additional, Wright, Melanie C., additional, Yu, Hong, additional, and Zhang, Jiajie, additional

Published
2023
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12. List of Contributors

Author

Ash, Joan S., primary, Bates, David W., additional, Callahan, Alison, additional, Cheung, Ngai T., additional, Cresswell, Kathrin M., additional, Frisse, Mark E., additional, Greaves, Felix, additional, Greenes, Robert A., additional, Halamka, John D., additional, Hall, Peter S., additional, Kohane, Isaac S., additional, Landman, Adam B., additional, Lorenzi, Nancy M., additional, Mandel, Joshua C., additional, Mandl, Kenneth D., additional, Manrai, Arjun K., additional, Middleton, Blackford, additional, Mizani, Mehrdad A., additional, Morris, Andrew, additional, Pfiffner, Pascal B., additional, Rozenblum, Ronen, additional, Schiff, Gordon D., additional, Shah, Nigam H., additional, Sheikh, Aziz, additional, Singh, Hardeep, additional, Singh, Karandeep, additional, Sittig, Dean F., additional, Slight, Sarah P., additional, Tharayil, Mary J., additional, and Wright, Adam, additional

Published
2017
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21. Contributors

Author

Ash, Joan S., primary, Bates, David W., additional, Biondich, Paul, additional, Boxwala, Aziz A., additional, Brown, Steven H., additional, Cimino, James J., additional, Col, Nananda, additional, Correa-de-Araujo, Rosaly, additional, Coyle, Joseph F., additional, Dahabreh, Issa J., additional, Dixon, Brian E., additional, Downs, Steve, additional, Drohan, Brian, additional, Duke, Jon, additional, Eisenberg, Floyd, additional, Scott Evans, R., additional, Del Fiol, Guilherme, additional, Franklin, Amy, additional, Fraser, Hamish, additional, Fry, Emory, additional, Glaser, John, additional, González-Ferrer, Arturo, additional, Grannis, Shaun, additional, Greenes, Robert A., additional, Gundlapalli, Adi V., additional, Hartzog, Timothy H., additional, Hongsermeier, Tonya, additional, Huff, Stanley M., additional, Hughes, Kevin S., additional, Jenders, Robert A., additional, Kawamoto, Kensaku, additional, Krall, Michael A., additional, Lau, Joseph, additional, Levick, Donald, additional, Mamlin, Burke, additional, Matheny, Michael E., additional, Maviglia, Saverio M., additional, Miller, Randolph A., additional, Ohno-Machado, Lucila, additional, Oniki, Thomas A., additional, Osheroff, Jerome, additional, Parker, Craig G., additional, Patel, Vimla L., additional, Peleg, Mor, additional, Rector, Alan, additional, Rocha, Roberto A., additional, Rocha, Beatriz H., additional, Samore, Matthew H., additional, Sordo, Margarita, additional, Schmid, Christopher H., additional, Shortliffe, Edward H., additional, Sottara, Davide, additional, Takesue, Blaine, additional, Tierney, William, additional, Trikalinos, Thomas A., additional, Wallace, Byron C., additional, Welch, Brandon M., additional, Wright, Adam, additional, Wyatt, Jeremy, additional, Yu, Hong, additional, and Zhang, Jiajie, additional

Published
2014
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28. Clinical decision support models and frameworks: Seeking to address research issues underlying implementation successes and failures.

Author

Greenes RA, Bates DW, Kawamoto K, Middleton B, Osheroff J, and Shahar Y

Subjects
Humans, Decision Support Systems, Clinical, Decision Support Techniques
Abstract

Computer-based clinical decision support (CDS) has been pursued for more than five decades. Despite notable accomplishments and successes, wide adoption and broad use of CDS in clinical practice has not been achieved. Many issues have been identified as being partially responsible for the relatively slow adoption and lack of impact, including deficiencies in leadership, recognition of purpose, understanding of human interaction and workflow implications of CDS, cognitive models of the role of CDS, and proprietary implementations with limited interoperability and sharing. To address limitations, many approaches have been proposed and evaluated, drawing on theoretical frameworks, as well as management, technical and other disciplines and experiences. It seems clear, because of the multiple perspectives involved, that no single model or framework is adequate to encompass these challenges. This Viewpoint paper seeks to review the various foci of CDS and to identify aspects in which theoretical models and frameworks for CDS have been explored or could be explored and where they might be expected to be most useful., (Copyright © 2017 Elsevier Inc. All rights reserved.)

Published
2018
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29. Healthcare academic informatics and IT vendors - A modest proposal for a collaborative focus.

Author

Hammond WE and Greenes RA

Subjects
Commerce, Community-Institutional Relations, Cooperative Behavior, Electronic Health Records, Health Care Costs, Humans, Interinstitutional Relations, Medical Informatics economics, Medical Informatics standards, Patient-Centered Care, Societies, Medical, United States, Medical Informatics organization & administration
Published
2016
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30. Design and implementation of the GLIF3 guideline execution engine.

Author

Wang D, Peleg M, Tu SW, Boxwala AA, Ogunyemi O, Zeng Q, Greenes RA, Patel VL, and Shortliffe EH

Subjects
Software Design, Database Management Systems, Decision Support Systems, Clinical, Medical Records Systems, Computerized standards, Practice Guidelines as Topic, Software, User-Computer Interface
Abstract

We have developed the GLIF3 Guideline Execution Engine (GLEE) as a tool for executing guidelines encoded in the GLIF3 format. In addition to serving as an interface to the GLIF3 guideline representation model to support the specified functions, GLEE provides defined interfaces to electronic medical records (EMRs) and other clinical applications to facilitate its integration with the clinical information system at a local institution. The execution model of GLEE takes the "system suggests, user controls" approach. A tracing system is used to record an individual patient's state when a guideline is applied to that patient. GLEE can also support an event-driven execution model once it is linked to the clinical event monitor in a local environment. Evaluation has shown that GLEE can be used effectively for proper execution of guidelines encoded in the GLIF3 format. When using it to execute each guideline in the evaluation, GLEE's performance duplicated that of the reference systems implementing the same guideline but taking different approaches. The execution flexibility and generality provided by GLEE, and its integration with a local environment, need to be further evaluated in clinical settings. Integration of GLEE with a specific event-monitoring and order-entry environment is the next step of our work to demonstrate its use for clinical decision support. Potential uses of GLEE also include quality assurance, guideline development, and medical education.

Published
2004
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31. GLIF3: a representation format for sharable computer-interpretable clinical practice guidelines.

Author

Boxwala AA, Peleg M, Tu S, Ogunyemi O, Zeng QT, Wang D, Patel VL, Greenes RA, and Shortliffe EH

Subjects
Database Management Systems, Databases, Factual, Systems Integration, United States, User-Computer Interface, Artificial Intelligence, Decision Support Systems, Clinical, Information Dissemination methods, Information Storage and Retrieval methods, Natural Language Processing, Practice Guidelines as Topic, Practice Patterns, Physicians' standards
Abstract

The Guideline Interchange Format (GLIF) is a model for representation of sharable computer-interpretable guidelines. The current version of GLIF (GLIF3) is a substantial update and enhancement of the model since the previous version (GLIF2). GLIF3 enables encoding of a guideline at three levels: a conceptual flowchart, a computable specification that can be verified for logical consistency and completeness, and an implementable specification that is intended to be incorporated into particular institutional information systems. The representation has been tested on a wide variety of guidelines that are typical of the range of guidelines in clinical use. It builds upon GLIF2 by adding several constructs that enable interpretation of encoded guidelines in computer-based decision-support systems. GLIF3 leverages standards being developed in Health Level 7 in order to allow integration of guidelines with clinical information systems. The GLIF3 specification consists of an extensible object-oriented model and a structured syntax based on the resource description framework (RDF). Empirical validation of the ability to generate appropriate recommendations using GLIF3 has been tested by executing encoded guidelines against actual patient data. GLIF3 is accordingly ready for broader experimentation and prototype use by organizations that wish to evaluate its ability to capture the logic of clinical guidelines, to implement them in clinical systems, and thereby to provide integrated decision support to assist clinicians.

Published
2004
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