Search

Background: Assault-related injury is a devastating consequence of violence and is a prominent cause of morbidity and mortality in young age. However, reliable data sources are scarce and there has been a paucity of studies examining possible predisposing factors on the incidence of assault-related injury., Method: Logistic regression analyses were conducted to examine the effect of gender, indigenous status and remoteness to health services on sustaining assault-related injuries in patients aged 17 years and under by using data from the state-wide trauma registry in Queensland, Australia from 2005 to 2008., Results: A total of 282 assault-related injury cases were identified. Indigenous females were at the highest risk of sustaining assault-related injuries (odds ratio (OR): 15.3, 95% confidence interval (CI): 8.17-28.6), followed by indigenous males (OR: 6.55, 95% CI: 3.60-11.9) and non-indigenous males (OR: 2.82, 95% CI: 1.78-4.47). Males were at a significantly higher risk than females in the group aged 13-17 years (OR: 2.11, 95% CI: 1.34-3.31). Living in a regional area was associated with a lower risk compared to major cities for non-indigenous people (OR: 0.59, 95% CI: 0.44-0.78). Indigenous people were at higher risk of sustaining an assault-related injury than non-indigenous people in regional areas (OR: 4.8, 95% CI: 3.14-7.42) and in remote areas (OR: 10.1, 95% CI: 2.64-38.69)., Conclusions: The current study provides evidence of interaction effects among the predisposing factors. Identifying these factors is important to conduct effective preventive measures and trauma management plans focussing on high-risk groups of assault-related injuries in young age., (Crown Copyright © 2012. Published by Elsevier Ltd. All rights reserved.)

Introduction: There are few published data for the magnitude of injury-related health problems in indigenous people such as Aboriginal and Torres Strait Islanders. The objective of our study was to compare the characteristics and outcomes of injury in the indigenous population to the non-indigenous population, who are living in Queensland, Australia., Methods: Participants were injured patients who presented to the emergency department for treatment and admitted to 15 public hospitals participating in the Queensland Trauma Registry (QTR) during 2003-2005., Results: Amongst 38,036 injured patients, 1847 patients were identified as indigenous and 35,530 as non-indigenous. Compared to the non-indigenous group, the indigenous group was significantly younger with no difference by gender. The injury severity score (ISS) and percentage of major injury (ISS > or = 16) were lower in the indigenous group. Indigenous patients had a significantly higher percentage of penetrating type injuries compared to non-indigenous (19.5% vs. 12.5%). The age- and injury severity-adjusted mortality rate was also significantly higher in indigenous. In age-stratified logistic regression analysis, the injury severity-adjusted odds for mortality was 3.0 times higher [95% confidence interval (95% CI): 1.6-5.5] in the indigenous, compared to the non-indigenous group, in 40-64-year olds, whilst increased odds in other age groups were not statistically significant., Conclusion: Our results indicate that middle-aged indigenous patients are more likely to die due to injury compared to non-indigenous patients. This suggests that strategies are required to improve outcomes particularly in the most affected injury patient group., (2009 Elsevier Ltd. All rights reserved.)

We investigated the association between MRI detected brain lesions and levels of endogenous sex hormones in Japanese-American men aged 74-95 years. Logistic regression was used to estimate the association (OR (95% CI)) of MRI outcome with tertiles of bioavailable testosterone, 17beta estradiol and sex hormone binding globulin (SHBG). There was a significantly increased risk for cerebral atrophy in the highest tertile of testosterone (3.1 (1.2-7.8)) compared to the lowest. We also found that men with the highest estradiol had a higher risk of lacunes (1.92 (1.1-3.2)). These relationships did not change with adjustment for the other sex hormones, cardiovascular risk factors, or other brain lesions. In contrast, men with the highest SHBG had a lower risk both of cerebral atrophy and lacunes, after adjusting for sex hormones and cardiovascular risk factors. There were no associations between sex hormones and hippocampal atrophy, white matter lesions, and large infarcts. Because the levels of hormone were measured close in time to the acquisition of the MRI, these associations may reflect neurodegeneration in brain regions regulating hormone levels.