1. Lung Organ Failure Score (LOFS): probability of severe pulmonary organ failure after multiple injuries including chest trauma.
- Author
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Wutzler S, Wafaisade A, Maegele M, Laurer H, Geiger EV, Walcher F, Barker J, Lefering R, and Marzi I
- Subjects
- Adult, Female, Germany epidemiology, Humans, Injury Severity Score, Intensive Care Units, Logistic Models, Lung Injury epidemiology, Lung Injury etiology, Male, Middle Aged, Multiple Trauma complications, Multiple Trauma epidemiology, Probability, Prognosis, Respiratory Distress Syndrome epidemiology, Thoracic Injuries epidemiology, Thoracic Injuries etiology, Tomography, X-Ray Computed, Lung Injury diagnosis, Multiple Trauma diagnosis, Organ Dysfunction Scores, Respiratory Distress Syndrome diagnosis, Thoracic Injuries diagnosis
- Abstract
Background: Pulmonary complications are common in multiple trauma patients with chest injury. Factors predisposing these critically ill patients to respiratory organ failure are not fully understood., Methods: Univariate and multivariate logistic regression analyses were used to assess the prognostic value of clinical and laboratory variables (2002-2008; n = 30,616) from the Trauma Registry of the German Trauma Society (DGU). Data from patients admitted to the ICU with lung contusion/lacerations, an Injury Severity Score ≥ 16 and age ≥ 18 were included in the study. Severe pulmonary organ failure was defined as PaO(2)/FiO(2)<200 for ≥ 3 days and based on the odds ratios (ORs) a simplified Lung Organ Failure Score (LOFS) was developed using integer values., Results: 21.3% (1254) of the 5892 patients analysed developed severe pulmonary organ failure. We identified seven independent predictors with significant correlation: age, gender, head injury, fluid therapy, injury severity, degree of chest trauma and surgical interventions. The highest ORs were observed in cases of Abbreviated Injury Scale (AIS)(Thorax) = 5 (1.58), surgical intervention (1.71) and multiple surgeries (2.41). We found that patients with simplified score values ≥ 21 points were at a maximum risk (>30%) for developing severe pulmonary complications., Conclusion: This scoring method could help trauma surgeons determine which multiple trauma patients are at risk for pulmonary complications after trauma. Efficacy analyses of prophylactic PEEP ventilation or rotational bed therapy in subgroups with comparable risks for respiratory complication could be based on the LOFS., (Copyright © 2010 Elsevier Ltd. All rights reserved.)
- Published
- 2012
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