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This is a comprehensive review of intraoperative, early postoperative, and late postoperative complications of Per Oral Endoscopic Myotomy with a focus on prevention, intraoperative management, and postoperative management., Competing Interests: Disclosure F. Khazoom: None. B.E. Louie: Consultant, Implantica; Data and Safety Monitoring Board: Omega Cuff, Aplos Medical., (Copyright © 2024 Elsevier Inc. All rights reserved.)

Objectives: To characterize rates, reasons for, and associated predictors for emergency department (ED) visits after breast cancer (BC) surgery., Methods: All women over 65 years undergoing curative surgery for non-metastatic incident BC (1998-2012) were identified using Quebec's universal healthcare administrative databases. Reasons for ED visits within 45days of operation were reported. Associated factors were estimated using Cox regression., Results: Of 24,463 patients, 12.8% had postoperative ED visits. Most frequent reasons were: superficial infection, noninfectious gastrointestinal, trauma or wound (other than breast), noninfectious respiratory, and breast wound disruption. Significant predictors included localized (aHR, 1.24, CI 1.04-1.49) or regional disease (aHR 1.64, CI 1.41-1.92), mastectomy (aHR 1.22, CI 1.10-1.34), each operation before definitive oncologic control (aHR 1.12, CI 1.03-1.21), lower institutional volume (aHR 1.23, CI 1.09-1.38), having 6-10 prescriptions (aHR 1.23, CI 1.15-1.31) or >10 (aHR 1.53, CI 1.33-1.77), benzodiazepine use (aHR 1.09, CI 1.01-1.18), anticoagulant use (aHR 1.29, CI 1.13-1.46), cardiovascular disease (aHR 1.15, CI 1.05-1.26), diabetes (aHR 1.11, CI 1.00-1.24), past hospitalization (aHR 1.25, CI 1.17-1.34), and lower income (aHR 1.12, CI 1.04-1.20)., Conclusion: Identification of risk factors in older patients before BC surgery could help prevent postoperative ED visits., (Copyright © 2017 Elsevier Ltd. All rights reserved.)