1. Information from the water stripe in TOCSY experiments on systems with exchangeable protons.
- Author
-
Nakashima TT, McClung RE, and Kotovych G
- Subjects
- Amino Acids chemistry, Carbon chemistry, Cysteine chemistry, Electron Spin Resonance Spectroscopy, Hydrogen chemistry, Hydroxyl Radical chemistry, Lysine chemistry, Models, Chemical, Nitrogen chemistry, Peptides chemistry, Protons, Solvents chemistry, Sucrose chemistry, Threonine chemistry, Time Factors, Tyrosine chemistry, Magnetic Resonance Spectroscopy methods, Water chemistry
- Abstract
The water "stripes" of the TOCSY maps of aqueous solutions of sucrose, of a 15-aminoacid peptide, and of several of the constituent aminoacids are shown to contain correlations at the resonance frequencies of protons which are scalar coupled to OH or NH protons which exchange with the solvent. Theoretical analysis of chemical exchange during the spin-lock period in TOCSY elucidates the origin of these correlations, and shows that their intensities vary with the duration of the spin-lock period and with the exchange rate., (Copyright 1998 Academic Press.)
- Published
- 1998
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