18 results on '"Krebs, Georgina"'
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2. Contributors
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Abramowitz, Jonathan S., primary, Banneyer, Kelly N., additional, Eugenio Cavanna, Andrea, additional, Fletcher, Terri L., additional, Hellberg, Samantha N., additional, Hundt, Natalie, additional, Jassi, Amita, additional, Krebs, Georgina, additional, McKay, Dean, additional, Puryear, Lucy J., additional, Treece, Christina A., additional, Van Kirk, Nathaniel, additional, Wu, Monica S., additional, and Zickgraf, Hana F., additional
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- 2020
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3. Contributors
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Andrade, Joy K.L., primary, Chambers, Nola J., additional, Chen, Yi-Lung, additional, Clark, Bruce, additional, Coghill, David, additional, Cottrell, Dominic, additional, Dadds, Mark, additional, Dawson-Squibb, John-Joe, additional, Delfabbro, Paul H., additional, de Vries, Petrus J., additional, Eapen, Valsamma, additional, Franz, Lauren, additional, Fung, Daniel Shuen Sheng, additional, Gau, Susan Shur-Fen, additional, Guerrero, Anthony P.S., additional, Harty, Michal, additional, Hirota, Tomoya, additional, Hong, Yun-Chul, additional, Jang, Yoonyoung, additional, Kato, Takahiro A., additional, King, Daniel L., additional, Krebs, Georgina, additional, Lee, Nami, additional, Lewis, Angela, additional, Mendoza Diaz, Antonio, additional, Poremski, Daniel, additional, Prescott, Susan, additional, Schlebusch, Liezl, additional, Seth, Sarah, additional, Skokauskas, Norbert, additional, Woolfenden, Susan, additional, and Zheng, Yi, additional
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- 2020
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4. Treatment of obsessive-compulsive disorder in a young person with autism spectrum disorder
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Jassi, Amita, primary and Krebs, Georgina, additional
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- 2020
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5. Relapse Prevention Strategies for Young People With OCD (After CBT)
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Krebs, Georgina, primary and Lewis, Angela, additional
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- 2018
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6. Working With Challenging Young People and Families
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Jassi, Amita, primary and Krebs, Georgina, additional
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- 2018
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7. Contributors
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Bergman, R. Lindsey, primary, Berryhill, Joseph, additional, Blakey, Shannon M., additional, Bloch, Michael H., additional, Brennan, Elle, additional, Farrell, Nicholas R., additional, Flessner, Christopher A., additional, Francazio, Sarah, additional, Herren, Jenny, additional, Ivarsson, Tord, additional, Jassi, Amita, additional, Johnco, Carly, additional, Jordan, Cary, additional, Krebs, Georgina, additional, Lebowitz, Eli R., additional, Lewis, Angela, additional, Mathews, Rachel E., additional, McGuire, Joseph F., additional, McKay, Dean, additional, Murphy, Yolanda E., additional, Oar, Ella L., additional, Peris, Tara S., additional, Dobrinsky, Stacey Rice, additional, Rozenman, Michelle, additional, Skarphedinsson, Gudmundur, additional, Storch, Eric A., additional, Sulkowski, Michael L., additional, Thomas, Benjamin E., additional, Turner, Cynthia M., additional, Vreeland, Allison, additional, Weidle, Bernhard, additional, and Williams, Tim I., additional
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- 2018
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8. Epidemiology of Body Dysmorphic Disorder and Appearance Preoccupation in Youth: Prevalence, Comorbidity and Psychosocial Impairment.
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Krebs G, Clark BR, Ford TJ, and Stringaris A
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Objective: Little is known about how common and impairing body dysmorphic disorder (BDD) is in the general population of youth. We evaluated the prevalence, comorbidity, and psychosocial impairment associated with BDD and more broadly defined appearance preoccupation in young people., Method: Data were drawn from the 2017 Mental Health of Children and Young People in England survey. BDD and psychiatric comorbidity were assessed in individuals 5 to 19 years of age (N = 7,654) according to DSM-5 criteria, using a clinician-rated standardized diagnostic assessment. Psychosocial impairment was measured with a quantitative scale and was indexed by reported self-harm and suicide attempts, as well as service use, assessed using structured interviews., Results: The point prevalence of BDD was 1.0% (95% CI = 0.8%-1.3%). BDD was significantly more common among adolescents than children (1.9 vs 0.1%; OR = 22.5, p < .001), and among female than male participants (1.8% vs 0.3%; OR = 7.3, p < .001). Approximately 70% of young people with BDD had psychiatric comorbidity, most commonly internalizing disorders. BDD was associated with self- and parent-reported psychosocial impairment, self-harm and suicide attempts, and service utilization. Appearance preoccupation was more common than full-syndrome BDD, but showed similar age and sex effects, patterns of comorbidity, and associated impairment., Conclusion: BDD and appearance preoccupation are relatively common, especially among adolescent girls, and are associated with substantial co-occurring psychopathology, impairment, and risk. Improved screening is needed to increase detection and diagnosis of BDD, and to facilitate access to evidence-based treatment., Study Preregistration Information: The epidemiology of body dysmorphic disorder the youth: prevalence, comorbidity and psychosocial impact; https://osf.io/g83jy., (Copyright © 2024 American Academy of Child and Adolescent Psychiatry. Published by Elsevier Inc. All rights reserved.)
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- 2024
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9. Effectiveness of Multimodal Treatment for Young People With Body Dysmorphic Disorder in Two Specialist Clinics.
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Rautio D, Gumpert M, Jassi A, Krebs G, Flygare O, Andrén P, Monzani B, Peile L, Jansson-Fröjmark M, Lundgren T, Hillborg M, Silverberg-Mörse M, Clark B, Fernández de la Cruz L, and Mataix-Cols D
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- Adolescent, Child, Combined Modality Therapy, Humans, Time, Treatment Outcome, Body Dysmorphic Disorders psychology, Body Dysmorphic Disorders therapy, Cognitive Behavioral Therapy
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Body dysmorphic disorder (BDD) typically originates in adolescence and is associated with considerable adversity. Evidence-based treatments exist but research on clinical outcomes in naturalistic settings is extremely scarce. We evaluated the short- and long-term outcomes of a large cohort of adolescents with BDD receiving specialist multimodal treatment and examined predictors of symptom improvement. We followed 140 young people (age range 10-18) with a diagnosis of BDD treated at two national and specialist outpatient clinics in Stockholm, Sweden (n = 96) and London, England (n = 44), between January 2015 and April 2021. Participants received multimodal treatment consisting of cognitive behavior therapy and, in 72% of cases, medication (primarily selective serotonin reuptake inhibitors). Data were collected at baseline, posttreatment, and 3, 6, and 12 months after treatment.The primary outcome measure was the clinician-rated Yale-Brown Obsessive-Compulsive Scale Modified for BDD, Adolescent version (BDD-YBOCS-A). Secondary outcomes included self-reported measures of BDD symptoms, depressive symptoms, and global functioning. Mixed-effects regression models showed that BDD-YBOCS-A scores decreased significantly from baseline to posttreatment (coefficient [95% confidence interval] = -16.33 [-17.90 to -14.76], p<0.001; within-group effect size (Cohen's d) = 2.08 (95% confidence interval, 1.81 to 2.35). At the end of the treatment, 79% of the participants were classified as responders and 59% as full or partial remitters. BDD symptoms continued to improve throughout the follow-up. Improvement was also seen on all secondary outcome measures. Linear regression models identified baseline BDD symptom severity as a predictor of treatment outcome at posttreatment, but no consistent predictors were found at the 12-month follow-up. To conclude, multimodal treatment for adolescent BDD is effective in both the short- and long-term when provided flexibly within a specialist setting. Considering the high personal and societal costs of BDD, specialist care should be made more widely available., (Copyright © 2022. Published by Elsevier Ltd.)
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- 2022
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10. Comparison of symptom-based versus self-reported diagnostic measures of anxiety and depression disorders in the GLAD and COPING cohorts.
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Davies MR, Buckman JEJ, Adey BN, Armour C, Bradley JR, Curzons SCB, Davies HL, Davis KAS, Goldsmith KA, Hirsch CR, Hotopf M, Hübel C, Jones IR, Kalsi G, Krebs G, Lin Y, Marsh I, McAtarsney-Kovacs M, McIntosh AM, Mundy J, Monssen D, Peel AJ, Rogers HC, Skelton M, Smith DJ, Ter Kuile A, Thompson KN, Veale D, Walters JTR, Zahn R, Breen G, and Eley TC
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- Adaptation, Psychological, Anxiety, Anxiety Disorders diagnosis, Anxiety Disorders epidemiology, Depression, Humans, Self Report, Depressive Disorder, Major epidemiology
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Background: Understanding and improving outcomes for people with anxiety or depression often requires large sample sizes. To increase participation and reduce costs, such research is typically unable to utilise "gold-standard" methods to ascertain diagnoses, instead relying on remote, self-report measures., Aims: Assess the comparability of remote diagnostic methods for anxiety and depression disorders commonly used in research., Method: Participants from the UK-based GLAD and COPING NBR cohorts (N = 58,400) completed an online questionnaire between 2018 and 2020. Responses to detailed symptom reports were compared to DSM-5 criteria to generate symptom-based diagnoses of major depressive disorder (MDD), generalised anxiety disorder (GAD), specific phobia, social anxiety disorder, panic disorder, and agoraphobia. Participants also self-reported any prior diagnoses from health professionals, termed self-reported diagnoses. "Any anxiety" included participants with at least one anxiety disorder. Agreement was assessed by calculating accuracy, Cohen's kappa, McNemar's chi-squared, sensitivity, and specificity., Results: Agreement between diagnoses was moderate for MDD, any anxiety, and GAD, but varied by cohort. Agreement was slight to fair for the phobic disorders. Many participants with self-reported GAD did not receive a symptom-based diagnosis. In contrast, symptom-based diagnoses of the phobic disorders were more common than self-reported diagnoses., Conclusions: Agreement for MDD, any anxiety, and GAD was higher for cases in the case-enriched GLAD cohort and for controls in the general population COPING NBR cohort. For anxiety disorders, self-reported diagnoses classified most participants as having GAD, whereas symptom-based diagnoses distributed participants more evenly across the anxiety disorders. Further validation against gold standard measures is required., (Copyright © 2021 The Authors. Published by Elsevier Ltd.. All rights reserved.)
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- 2022
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11. Is poor global processing a transdiagnostic feature of Body Dysmorphic Disorder and Anorexia Nervosa? A meta-analysis.
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Lang K, Kerr-Gaffney J, Hodsoll J, Jassi A, Tchanturia K, and Krebs G
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- Anorexia Nervosa psychology, Body Dysmorphic Disorders psychology, Humans, Randomized Controlled Trials as Topic, Anorexia Nervosa diagnosis, Body Dysmorphic Disorders diagnosis, Body Image psychology, Visual Perception physiology
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Body dysmorphic disorder (BDD) and anorexia nervosa (AN) are characterised by body image disturbance. It has been suggested that poor global integration in visual processing may underlie distorted body image, but empirical studies have yielded mixed results. The current study involved two meta-analyses aimed at examining the extent to which poor global processing is evident in BDD and AN. Studies were identified through a systematic literature search up to October 2020. The BDD search yielded 16 studies and the AN search yielded 18 studies. Random-effect models demonstrated a small pooled effect size for BDD (g = -0.44, 95 % CI -0.70, -0.17, p < 0.001) and a moderate pooled effect size for AN (g = -0.63, 95 % CI -0.77, -0.49, p < .001), with no evidence of significant publication bias for either. The results provide evidence that poor global processing is a transdiagnostic feature of both BDD and AN, although effects may be more pronounced in AN. Our findings highlight the possibility that interventions aimed at promoting global visual processing could prove beneficial in disorders characterised by distorted body image., (Copyright © 2021 Elsevier Ltd. All rights reserved.)
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- 2021
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12. Clinician-reported barriers to using exposure with response prevention in the treatment of paediatric obsessive-compulsive disorder.
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Keleher J, Jassi A, and Krebs G
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Exposure techniques are underutilised in the treatment of anxiety disorders in routine practice, but little is known about the use of exposure with response prevention (ERP) for OCD, particularly in youth. The current study aimed to examine the utilisation of ERP for paediatric OCD via an anonymous online survey completed by clinicians ( N = 107). Specifically, we explored the association of clinician characteristics and OCD symptom subtypes with ERP use, as well as clinician-reported barriers to ERP implementation. The majority of clinicians reported commonly using ERP when treating youth with OCD, and rates of ERP use were highest among clinical psychologists. Clinician-held negative beliefs about exposure were significantly associated with lower ERP use. Additionally, clinicians reported being less likely to use ERP to treat hoarding symptoms and taboo obsessions, compared to other OCD symptom subtypes. The most commonly endorsed barriers to successful ERP implementation were aspects of the phenomenology of OCD (e.g. covert compulsions, frequently changing rituals) as opposed to general barriers (e.g. insufficient time during sessions). Overall, our findings suggest that OCD presents unique challenges for clinicians delivering exposure-based therapy. Training should address these OCD-specific obstacles in order to promote dissemination of ERP for youth with OCD., (© 2019 The Authors.)
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- 2020
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13. Is perfectionism a risk factor for adolescent body dysmorphic symptoms? Evidence for a prospective association.
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Krebs G, Quinn R, and Jassi A
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The current study tested the hypothesis that perfectionism is a risk factor for the development of body dysmorphic disorder (BDD), as proposed by prevailing cognitive behavioural models. School students aged 14-16 years completed questionnaires 6 months apart (Time 1: N = 302; Time 2: N = 68) assessing perfectionism, BDD symptoms, and anxiety and depression. Robust regression models tested concurrent and prospective associations between perfectionism and BDD symptoms, with and without adjustment for coexisting anxiety and depression. Total perfectionism was positively associated with concurrent BDD symptoms, even when controlling for coexisting anxiety and depression. Moreover, total perfectionism predicted changes in BDD symptoms between Time 1 and Time 2. Examination of perfectionism subscales indicated that only self-oriented perfectionism, not socially-prescribed perfectionism, predicted BDD symptoms concurrently and prospectively while controlling for coexisting psychopathology. This study provides preliminary evidence for self-oriented perfectionism being a risk factor for the development of BDD in youth. If replicated, these findings could highlight the potential value of targeting self-oriented perfectionism in prevention and early intervention programs for BDD.
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- 2019
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14. Long-Term Outcomes of Cognitive-Behavioral Therapy for Adolescent Body Dysmorphic Disorder.
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Krebs G, Fernández de la Cruz L, Monzani B, Bowyer L, Anson M, Cadman J, Heyman I, Turner C, Veale D, and Mataix-Cols D
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- Adolescent, Body Dysmorphic Disorders psychology, Depression psychology, Female, Follow-Up Studies, Humans, Male, Quality of Life, Randomized Controlled Trials as Topic, Treatment Outcome, Body Dysmorphic Disorders therapy, Cognitive Behavioral Therapy methods, Time
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Emerging evidence suggests that cognitive-behavioral therapy (CBT) is an efficacious treatment for adolescent body dysmorphic disorder (BDD) in the short term, but longer-term outcomes remain unknown. The current study aimed to follow up a group of adolescents who had originally participated in a randomized controlled trial of CBT for BDD to determine whether treatment gains were maintained. Twenty-six adolescents (mean age = 16.2, SD = 1.6) with a primary diagnosis of BDD received a course of developmentally tailored CBT and were followed up over 12 months. Participants were assessed at baseline, midtreatment, posttreatment, 2-, 6-, and 12-month follow-up. The primary outcome measure was the clinician-rated Yale-Brown Obsessive-Compulsive Scale Modified for BDD. Secondary outcomes included measures of insight, depression, quality of life, and global functioning. BDD symptoms decreased significantly from pre- to posttreatment and remained stable over the 12-month follow-up. At this time point, 50% of participants were classified as responders and 23% as remitters. Participants remained significantly improved on all secondary outcomes at 12-month follow-up. Neither baseline insight nor baseline depression predicted long-term outcomes. The positive effects of CBT appear to be durable up to 12-month follow-up. However, the majority of patients remained symptomatic and vulnerable to a range of risks at 12-month follow-up, indicating that longer-term monitoring is advisable in this population. Future research should focus on enhancing the efficacy of CBT in order to improve long-term outcomes., (Copyright © 2017. Published by Elsevier Ltd.)
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- 2017
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15. A critical review of cosmetic treatment outcomes in body dysmorphic disorder.
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Bowyer L, Krebs G, Mataix-Cols D, Veale D, and Monzani B
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- Body Dysmorphic Disorders psychology, Humans, Treatment Outcome, Body Dysmorphic Disorders diagnosis, Body Dysmorphic Disorders surgery, Body Image, Cosmetic Techniques psychology, Surgery, Plastic methods
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A high proportion of individuals with body dysmorphic disorder (BDD) undergo cosmetic treatments in an attempt to 'fix' perceived defect/s in their physical appearance. Despite the frequency with which such procedures are sought, few studies have prospectively examined the outcomes of cosmetic procedures in individuals with BDD. This article aims to critically review the literature and discuss the current debate that exists on outcomes of cosmetic treatment for individuals with BDD. An emerging literature suggests the majority of individuals with BDD have poor outcomes after cosmetic interventions; however, based on the current literature, it cannot be fully ruled out that certain individuals with mild BDD and localised appearance concerns may benefit from these interventions. Gaps in the current literature are highlighted, alongside recommendations for future research. Carefully conducted longitudinal studies with well-characterised patient populations are needed., (Copyright © 2016 Elsevier Ltd. All rights reserved.)
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- 2016
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16. Evaluation of cognitive behaviour therapy for paediatric obsessive-compulsive disorder in the context of tic disorders.
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Bennett S, Stark D, Shafran R, Heyman I, and Krebs G
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- Adolescent, Analysis of Variance, Case-Control Studies, Child, Female, Follow-Up Studies, Humans, Male, Psychiatric Status Rating Scales, Retrospective Studies, Treatment Outcome, Cognitive Behavioral Therapy methods, Obsessive-Compulsive Disorder complications, Obsessive-Compulsive Disorder psychology, Obsessive-Compulsive Disorder rehabilitation, Tic Disorders complications, Tic Disorders rehabilitation
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Background and Objectives: Paediatric obsessive-compulsive disorder (OCD) and tic disorders (TD) often present together. However, there has been relatively little research on whether comorbid tic disorders influence response to cognitive behaviour therapy (CBT) for OCD. This study aimed to examine the outcomes of CBT for paediatric patients with OCD and a tic disorder compared to a matched group of children with OCD and no tics. Outcomes were compared post-treatment and at 3 or 6 month follow-up., Methods: Participants were 29 young people with tic disorders and OCD (OCD + TD) and 29 young people with OCD without tic disorders (OCD-TD) who were matched according to age, gender and baseline OCD symptom severity. All participants received a course of CBT and outcomes were assessed using the Children's Yale-Brown Obsessive-Compulsive Scale (CY-BOCS)., Results: OCD symptoms reduced over the course of CBT to an equivalent extent in the OCD + TD and OCD-TD groups. Response or remission rates did not differ significantly at either post-intervention or follow-up between those with OCD + TD and those with OCD-TD. For both groups, response rates were high - 72% of both groups were classified as responders post-intervention and, at follow-up, 81% of the OCD + TD group and 82% of the OCD no tics group responded. Those with OCD + TD responded in significantly fewer sessions than those with OCD without tics., Limitations: A number of potential confounding factors were not assessed and therefore could not be controlled for, such as other comorbidities and stability of medication., Conclusions: Paediatric patients with OCD and tic disorders respond equally well to standard CBT for OCD as compared to those with OCD and no tics., (Copyright © 2015 Elsevier Ltd. All rights reserved.)
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- 2015
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17. A Pilot Randomized Controlled Trial of Cognitive-Behavioral Therapy for Adolescents With Body Dysmorphic Disorder.
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Mataix-Cols D, Fernández de la Cruz L, Isomura K, Anson M, Turner C, Monzani B, Cadman J, Bowyer L, Heyman I, Veale D, and Krebs G
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- Adolescent, Female, Humans, Logistic Models, London, Male, Pilot Projects, Psychiatric Status Rating Scales, Quality of Life psychology, Severity of Illness Index, Single-Blind Method, Treatment Outcome, Body Dysmorphic Disorders therapy, Cognition, Cognitive Behavioral Therapy, Depression
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Objective: Body dysmorphic disorder (BDD) typically starts in adolescence, but evidence-based treatments are yet to be developed and formally evaluated in this age group. We designed an age-appropriate cognitive-behavioral therapy (CBT) protocol for adolescents with BDD and evaluated its acceptability and efficacy in a pilot randomized controlled trial., Method: Thirty adolescents aged 12 to 18 years (mean = 16.0, SD = 1.7) with a primary diagnosis of BDD, together with their families, were randomly assigned to 14 sessions of CBT delivered over 4 months or a control condition of equivalent duration, consisting of written psycho-education materials and weekly telephone monitoring. Blinded evaluators assessed participants at baseline, midtreatment, posttreatment, and at 2-month follow-up. The primary outcome measure was the Yale-Brown Obsessive-Compulsive Scale Modified for BDD, Adolescent Version (mean baseline score = 37.13, SD = 4.98, range = 24-43)., Results: The CBT group showed a significantly greater improvement than the control group, both at posttreatment (time × group interaction coefficient [95% CI] = -11.26 [-17.22 to -5.31]; p = .000) and at 2-month follow-up (time × group interaction coefficient [95% CI] = -9.62 [-15.74 to -3.51]; p = .002). Six participants (40%) in the CBT group and 1 participant (6.7%) in the control condition were classified as responders at both time points (χ(2) = 4.658, p = .031). Improvements were also seen on secondary measures, including insight, depression, and quality of life at posttreatment. Both patients and their families deemed the treatment as highly acceptable., Conclusion: Developmentally tailored CBT is a promising intervention for young people with BDD, although there is significant room for improvement. Further clinical trials incorporating lessons learned in this pilot study and comparing CBT and pharmacological therapies, as well as their combination, are warranted., Clinical Trial Registration Information: Cognitive-Behaviour Therapy for Adolescents With Body Dysmorphic Disorder; http://www.isrctn.com/; ISRCTN67699666., (Copyright © 2015 American Academy of Child and Adolescent Psychiatry. Published by Elsevier Inc. All rights reserved.)
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- 2015
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18. Telephone cognitive-behavioral therapy for adolescents with obsessive-compulsive disorder: a randomized controlled non-inferiority trial.
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Turner CM, Mataix-Cols D, Lovell K, Krebs G, Lang K, Byford S, and Heyman I
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- Adolescent, Child, Female, Humans, Male, Parents, Treatment Outcome, Cognitive Behavioral Therapy methods, Obsessive-Compulsive Disorder therapy, Telephone
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Objective: Many adolescents with obsessive-compulsive disorder (OCD) do not have access to evidence-based treatment. A randomized controlled non-inferiority trial was conducted in a specialist OCD clinic to evaluate the effectiveness of telephone cognitive-behavioral therapy (TCBT) for adolescents with OCD compared to standard clinic-based, face-to-face CBT., Method: Seventy-two adolescents, aged 11 through 18 years with primary OCD, and their parents were randomized to receive specialist TCBT or CBT. The intervention provided differed only in the method of treatment delivery. All participants received up to 14 sessions of CBT, incorporating exposure with response prevention (E/RP), provided by experienced therapists. The primary outcome measure was the Children's Yale-Brown Obsessive-Compulsive Scale (CY-BOCS). Blind assessor ratings were obtained at midtreatment, posttreatment, 3-month, 6-month, and 12-month follow-up., Results: Intent-to-treat analyses indicated that TCBT was not inferior to face-to-face CBT at posttreatment, 3-month, and 6-month follow-up. At 12-month follow-up, there were no significant between-group differences on the CY-BOCS, but the confidence intervals exceeded the non-inferiority threshold. All secondary measures confirmed non-inferiority at all assessment points. Improvements made during treatment were maintained through to 12-month follow-up. Participants in each condition reported high levels of satisfaction with the intervention received., Conclusion: TCBT is an effective treatment and is not inferior to standard clinic-based CBT, at least in the midterm. This approach provides a means of making a specialized treatment more accessible to many adolescents with OCD. Clinical trial registration information-Evaluation of telephone-administered cognitive-behaviour therapy (CBT) for young people with obsessive-compulsive disorder (OCD); http://www.controlled-trials.com; ISRCTN27070832., (Crown Copyright © 2014. Published by Elsevier Inc. All rights reserved.)
- Published
- 2014
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