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Study Objective: To assess whether volume of laparoscopic experience correlates with residents' performance on laparoscopic training drills., Design: Residents performed 4 laparoscopic drills in the inanimate laboratory: peg transfer, bean drop, rope pass, and triangle transfer. Performance times were recorded. Laparoscopic experience as primary surgeon was determined from resident case logs. The resident data were divided according to volume of laparoscopic experience (0-19, 20-39, > or =40 cases). Performance times were compared among the groups according to volume of laparoscopic surgical experience., Design Classification: II-3., Setting: This study was conducted in a university school of medicine surgical skills laboratory., Participants: Participants in this study were obstetrics and gynecology residents entering their second through fourth years of training., Interventions: Laparoscopic trainer drill performance times were recorded and correlated with amount of operative laparoscopic experience., Measurements and Main Results: In all, 25 residents participated. Only the peg transfer drill showed statistically significant correlation between faster performance time and increasing laparoscopic experience (p =.01). No significant association existed between laparoscopic experience and performance time on the bean drop, triangle transfer, or rope pass drills., Conclusion: Residents with more laparoscopic experience performed the peg transfer drill significantly faster than those with less experience.

Background: Concomitant use of antiretroviral (ARV) and hormonal contraceptives may change the metabolism of each and the resulting safety profiles. We evaluated the safety and tolerability of depot medroxyprogesterone acetate (DMPA) among women on ARV., Study Design: HIV-infected women on selected ARV regimens or no ARV were administered DMPA 150 mg intramuscularly and evaluated for 12 weeks for adverse events, changes in CD4+ count and HIV RNA levels, and ovulation., Results: Seventy evaluable subjects were included, 16 on nucleoside only or no ARV, 21 on nelfinavir-containing regimens, 17 on efavirenz-containing regimens and 16 on nevirapine-containing regimens. Nine Grade 3 or 4 adverse events occurred in seven subjects; none were judged related to DMPA. The most common findings possibly related to DMPA were abnormal vaginal bleeding (nine, 12.7%), headache (three, 4.2%), abdominal pain, mood changes, insomnia, anorexia and fatigue, each occurring in two (2.9%) subjects. No significant changes in CD4+ count or HIV RNA levels occurred with DMPA. No evidence of ovulation was detected, and no pregnancies occurred., Conclusions: The clinical profile associated with DMPA administration in HIV-infected women, most on ARV, appears similar to that seen in HIV-uninfected women. DMPA prevented ovulation and did not affect CD4+ counts or HIV RNA levels. In concert with previously published DMPA/ARV interaction data, these data suggest that DMPA can be used safely by HIV-infected women on the ARV studied.