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Introduction: This study aimed to investigate changes in bite force (BF) and occlusal contact area after anterior open-bite (AOB) treatment and compare the changes in surgical vs nonsurgical treatment., Methods: This retrospective study included patients with AOB compared with normal occlusion. AOB was corrected by either intrusion of the maxillary molars (intrusion group, n = 19) or orthognathic surgery (surgery group, n = 37). The control group (n = 35) had a normal overbite relationship. Records of lateral cephalograms, BF, and occlusal contact area taken before (T0), immediately after (T1), and 2 years after (T2) orthodontic treatment were compared within and among the 3 groups., Results: The open-bite group, including intrusion and surgery groups, had a lower BF and less occlusal contact area than the control group at T0 and T1 (P <0.001). However, there were no significant differences among the 3 groups at T2 (P >0.05). The intrusion and surgery groups showed no significant differences throughout the observation period extending from T0 to T2 (P >0.05). Although BF and occlusal contact area decreased at T1 compared with T0, they increased during retention and showed higher values at T2 than at T0., Conclusions: Treatment of AOB improved BF and occlusal contact area 2 years posttreatment. Orthognathic surgery and molar intrusion using orthodontic miniscrews can improve occlusal function similarly. Orthodontists can select either method depending on malocclusion severity and patient demand., (Copyright © 2023 American Association of Orthodontists. Published by Elsevier Inc. All rights reserved.)

Introduction: This study aimed to examine the stability of anterior open bite (AOB) treatment with clear aligners., Methods: This retrospective cohort study included 52 adult AOB patients (aged >18 years; 15 males, 37 females) who underwent nonextraction clear aligner treatment and were at least 1 year posttreatment. Eleven cephalometric measurements were evaluated at pretreatment, end of active treatment, and at least 1-year posttreatment. Overbite change, the primary outcome variable, and other cephalometric changes during treatment and retention were calculated, and repeated measures analysis of variance were performed. Stepwise multiple regression was used to make a prediction equation for open bite relapse., Results: The mean retention period was 2.1 ± 1.1 years. The mean change in overbite during treatment was 3.3 ± 1.5 mm; 6% of patients presented relapse at least 1 year after treatment completion. The mean change of overbite (0.2 ± 0.5 mm) during the retention period was not statistically significant (P = 0.59). None of the 11 cephalometric measurements showed significant change during the retention period. The prediction model showed that only the coefficient for a tongue posture issue at the initial examination was statistically significant., Conclusions: AOB was successfully corrected in all 52 patients using only clear aligners with no additional adjunctive aids such as microimplants. When retained with maxillary and mandibular fixed retainers and maxillary and mandibular vacuum-formed retainers, there was no significant change in cephalometric measurements during the short-term retention period., (Copyright © 2023 American Association of Orthodontists. Published by Elsevier Inc. All rights reserved.)

Introduction: Tooth size ratio is important for optimal dentofacial esthetics, occlusal interdigitation, and postorthodontic treatment stability. Tooth geometry influences tooth size ratio; therefore, tooth size normative data may not be practical across diverse ethnic groups. This study aimed to determine whether there are significant differences in 3-dimensional tooth size among patients in the Hispanic population with Angle Class I, II, and III malocclusions., Methods: The data were collected using intraoral scanned orthodontic study models representing Hispanic orthodontic patients with Angle Class I, II, and III malocclusions. The scanned models were digitized and transferred to a geometric morphometric system. Tooth sizes were determined, quantified, and visualized using contemporary geometric morphometric computational tools., Results: Tooth size was determined for all teeth and showed a significant difference in 4 out of 28 teeth: Maxillary right first molar, mandibular left second molar, mandibular right first molar and mandibular right second molar. This significant difference was noted among females and affected different malocclusion groups., Conclusions: Tooth size discrepancy in the Hispanic population varies among malocclusion groups, and the variation is determined by the participant's gender., (Copyright © 2023 American Association of Orthodontists. Published by Elsevier Inc. All rights reserved.)

Introduction: The objective of this study was to evaluate and compare the 3-dimensional (3D) aging changes of the lips among adult skeletal Class I, II, and III malocclusion., Methods: Female adult orthodontic patients aged 20-50 years with pretreatment cone-beam computed tomography scans were retrospectively classified according to age (20s [20-29 years], 30s [30-39 years], and 40s [40-49 years]) and then subclassified by malocclusion into skeletal Class I, II, and III relationship (9 groups; n = 30 per group). Positional differences in midsagittal and parasagittal soft-tissue landmarks and 3D morphologic aging changes of the lips were evaluated using cone-beam computed tomography scans., Results: Labiale superius and cheilion for patients in their 40s indicated a significant downward and backward position compared with those in their 20s, regardless of skeletal classifications (P <0.05). Accordingly, the upper lip height decreased, and the mouth width increased significantly (P <0.05). For Class III malocclusion, the upper lip vermilion angle was greater for patients in their 40s than those in their 20s (P <0.05), whereas the lower lip vermilion angle was only lower for patients with Class II malocclusion (P <0.05)., Conclusions: Middle-aged adult females (40-49 years) had a lower upper lip height and greater mouth width than those in their 20s, regardless of skeletal malocclusion. However, prominent morphologic aging changes of the lips were noted on the upper lip for skeletal Class III malocclusion and the lower lip for skeletal Class II malocclusion, implying that the underlying skeletal features (or malocclusion) may influence 3D aging changes of the lips., (Copyright © 2023 American Association of Orthodontists. Published by Elsevier Inc. All rights reserved.)

This study aims to critically review the literature in respect to craniofacial bone abnormalities and malocclusion in sickle cell anemia individuals. The Bireme and Pubmed electronic databases were searched using the following keywords: malocclusion, maxillofacial abnormalities, and Angle Class I, Class II and lass III malocclusions combined with sickle cell anemia. The search was limited to publications in English, Spanish or Portuguese with review articles and clinical cases being excluded from this study. Ten scientific publications were identified, of which three were not included as they were review articles. There was a consistent observation of orthodontic and orthopedic variations associated with sickle cell anemia, especially maxillary protrusions. However, convenience sampling, sometimes without any control group, and the lack of estimates of association and hypotheses testing undermined the possibility of causal inferences. It was concluded that despite the high frequency of craniofacial bone abnormalities and malocclusion among patients with sickle cell anemia, there is insufficient scientific proof that this disease causes malocclusion

Background: Clear aligners are reported to control anterior open bites. Despite this, anterior extrusion remains difficult with aligners. Optimized extrusion attachments on incisors may facilitate anterior extrusion to correct open bite with Invisalign. The aim of this retrospective study was to compare the efficacy of anterior open bite correction with Invisalign when using optimized extrusion versus conventional attachments., Methods: This was a retrospective cohort study. The pre- and post-treatment intraoral scans of patients with anterior open bite treated with Invisalign aligners were assessed. Patients were divided into two groups: group A, patients with horizontal conventional attachments and group B, patients with optimized extrusion attachments on incisors. The pre and post-treatment overbite and the planned overbite change were measured and compared between the groups. Descriptive statistics were computed and statistical significance was set at P < 0.05., Results: A total of 86 patients were included. Both groups showed significant increases in overbite, but there was no difference in the open bite correction efficacy in patients with conventional versus optimized attachments. Shorter treatment times for open bite closure were reported for patients with optimized attachments., Conclusions: Anterior open bite can be corrected regardless of the attachment type. Optimized attachments are no more effective than using conventional attachments in incisor extrusion to correct open bite. Patients with anterior open bite with optimized attachments observed shorter treatment times for overbite correction. When correcting anterior open bite with Invisalign, the attachment type does not improve the success rate. Optimized extrusion attachments on incisors may shorten the treatment time compared to conventional attachments., (Copyright © 2023 World Federation of Orthodontists. Published by Elsevier Inc. All rights reserved.)

Introduction: Mandibular micrognathism (MM) is an underdeveloped mandible resulting from complex interactions between genetic and environmental factors. Prior research focused mainly on the genetic determinants of mandibular retrognathism, not necessarily reflecting micrognathism, thus supporting the need to study MM. This study aimed to explore the inheritance pattern and identify the candidate genes involved in the development and familial transmission of MM., Methods: Diagnosing probands with MM was based on clinical and lateral cephalometric data. The pedigrees were drawn for 11 identified families, 5 of whom accepted to undergo detailed data and biospecimen collection. These families included 15 MM and 13 non-MM subjects over 2-3 generations. The procedure involved the withdrawal of 5 mL of blood. Genomic DNA was isolated from blood cells to investigate protein-coding regions via whole exome sequencing. Standardized filtering steps were employed, and candidate genes were identified., Results: Most of the pedigrees suggested a Mendelian inheritance pattern and segregated in an autosomal-dominant manner. One of the families, which also underwent biospecimen, displayed an X-linked inheritance pattern of the trait. Genetic screening disclosed 8 potentially novel genes (GLUD2, ADGRG4, ARSH, TGIF1, FGFR3, ZNF181, INTS7, and WNT6). None of the recognized exonic regions were previously reported., Conclusions: Eight novel genes were identified in association with MM in the largest number of families reported to date. The genes were X-linked in 1 family, a finding previously not observed in mandibular genetics., (Copyright © 2022 American Association of Orthodontists. Published by Elsevier Inc. All rights reserved.)

Introduction: This study aimed to identify the vertical radiographic changes in nongrowing patients after treatment of anterior open bites (AOBs) using mini-implant assisted intrusion and to provide a predictive model to quantify the achievable intrusion., Methods: This retrospective radiographic study evaluated the dentoskeletal changes in adults using orthodontic mini-implants in 53 treated patients with AOB. Radiographs before and after posterior intrusion were utilized to evaluate the associated changes. Conventional cephalometric analyses provided data for assessment. A paired t test was used to identify significant changes. A regression model (best subsets selection algorithm) was generated to quantify the relationship between mini-implant-assisted intrusion and the resultant change in overbite. A matched, untreated control sample was used for comparison., Results: One hundred percent of AOBs were corrected using mini-implant-assisted intrusion of the maxillary molars. The overbite increased by an average of 3.6 mm. The average amount of maxillary first molar intrusion was 2.67 mm. The mandibular first molar moved an average of 1.93 mm closer to the palatal plane because of an average clockwise mandibular rotation of 0.78°. The occlusal plane steepened by an average of 3.95°. If all other inputs are held constant, 1 mm of intrusion of the maxillary first molar results in a 0.86 mm increase in overbite., Conclusions: Mini-implant-assisted intrusion successfully treated AOB in adults with significant dentoalveolar but no significant skeletal changes. An average of 2.67 mm of intrusion of the maxillary first molars is achievable with this method showing that 1 mm of intrusion of the maxillary first molar increased overbite by 0.86 mm. Longer periods of intrusion resulted in greater amounts of bite closure., (Copyright © 2022 American Association of Orthodontists. Published by Elsevier Inc. All rights reserved.)

Introduction: Bonded spurs, fixed or removable palatal cribs have been used to treat anterior open bite (AOB) in growing children. Different conclusions have been brought out by different authors. This meta-analysis aimed to evaluate the effect of bonded spurs, fixed and removable palatal cribs in the early treatment of AOB., Methods: A comprehensive electronic search was carried out through PubMed, Embase (via Ovid), MEDLINE (via Ovid), Cochrane Central Register of Controlled Trials, and Web of Science up to May 1, 2022. This meta-analysis was performed in accordance with the Cochrane Handbook for Systematic Reviews of Interventions. The work was carried out by 2 reviewers in duplicate and independently, including electronic searching, data extracting, risk of bias assessment, quality of evidence grading, heterogeneity and statistical power analysis, and eligibility evaluation of the retrieved articles., Results: Four studies out of 181 articles were recruited in the meta-analysis after applying the inclusion and exclusion criteria. The results showed that bonded lingual spurs and fixed palatal crib or spurs produced similar overbite changes (mean difference, -0.32; 95% confidence interval, -1.06 to 0.43; P = 0.41; I 2  = 27%; meta power = 0.099). Fixed palatal crib and removable palatal crib also exhibited comparable effects in correcting AOB (mean difference, -0.02; 95% confidence interval, -0.90 to 0.86; P = 0.96; I 2  = 0%; meta power = 0.2182). The quality of evidence about these 2 outcomes assessed with GRADE (Grading of Recommendations, Assessment, Development, and Evaluations) was low., Conclusions: Bonded lingual spurs, fixed palatal crib or spurs, and removable palatal crib had similar effects in the early treatment of AOB. Because the number of included studies was limited and only the overbite changes before and after treatment were assessed, more clinical randomized controlled studies with longer follow-ups are needed to get more clinically significant advice., (Copyright © 2022. Published by Elsevier Inc.)

Introduction: Although the Invisalign appliance has reported difficulty in achieving the overbite outcomes predicted by ClinCheck software (Align Technology, Santa Clara, Calif), the effect of modifications to the material and components of the appliance are largely unquantified. This study aimed to investigate and determine the accuracy of Invisalign in correcting a deep overbite by comparing the predicted outcome from ClinCheck to the achieved posttreatment outcome for treatment groups that use different components of the appliance system., Methods: A retrospective study was conducted using pretreatment and posttreatment intraoral scans and predicted outcomes (ClinCheck) stereolithography files of 2 groups of consecutively treated adult patients from private specialist orthodontic practices, 1 group treated with EX30 material with no bite ramps (n = 29) and 1 treated with the newer SmartTrack material and precision bite ramps (n = 39). Inclusion criteria comprised nonextraction treatment, with a minimum of 14 dual arch Invisalign aligners using a 2-weekly aligner change protocol. Geomagic Control X software (3D Systems, Rock Hill, SC) was used to measure overbite in the pretreatment, posttreatment, and predicted outcome stereolithography files for each patient. Results were compared with a previously published treatment group that used SmartTrack material and no precision bite ramps., Results: The regression coefficient analysis indicated that for both groups, the deeper the pretreatment overbite and the greater overbite reduction projected according to ClinCheck, there is a linear increase in the discrepancy of overbite expression posttreatment. ClinCheck overpredicted overbite reduction in 96.6% of patients with precision bite ramp in which, on average, 43.4% of the prescribed overbite reduction was expressed. For EX30 patients, ClinCheck overpredicted overbite reduction in 87.2% of patients in which, on average, 55.1% of the prescribed overbite reduction was expressed., Conclusions: The use of precision bite ramps does not appear to significantly improve the ability of SmartTrack material to predictably open the bite. SmartTrack material with or without bite ramps does not appear to produce better bite opening predictability than that seen with EX30 material., (Copyright © 2022 American Association of Orthodontists. Published by Elsevier Inc. All rights reserved.)

Objective: The study aimed to clarify (1) the effect of the Beneslider distalization appliance on maxillary molars (M1+2), (2) the type of tooth movement, and (3) changes in skeletal parameters., Study Design: Dental distalization paths and transversal changes were measured according to the distance of the pterygoid vertical as well as on the virtualized 3D plaster model., Results: Distalization of the second premolar (P2; T1 - T2) was 2.51 mm (±1.81 mm; P < .001) combined with a distal tipping of 6.50° (±5.09°; P < .001), whereas for M1 a distalization of 3.49 mm (±1.10 mm) occurred with negligible tipping (0.73° ± 5.04°). No significant differences (T1 - T2) on sagittal and vertical skeletal variables were found within or between G1+2. In contrast, a significant increase in N-Sp' in G2 and in Sp'-Gn in G1+2 with consecutive Hasund index reduction was shown. Comparing T1 and T2, the device had an effect on the transversal development., Conclusion: The Beneslider distalization appliance causes an effective distalization of M1+2, with slight second premolar tipping. No modification of skeletal parameters was recorded, but a relevant effect on Hasund index and the transverse was found., (Copyright © 2021 Elsevier Inc. All rights reserved.)

A double J retractor and palatal miniscrews were applied to retract maxillary anterior teeth without brackets after repeated periodontal flare-ups. The line of action passing through the center of resistance of maxillary anterior teeth and the moment generated by palatal miniscrews via torquing springs successfully controlled the overbite and incisor torque during space closure. In addition to en-masse retraction without brackets, it is also possible to combine this setup with labial fixed appliances or clear aligner treatment., (Copyright © 2021 American Association of Orthodontists. Published by Elsevier Inc. All rights reserved.)

A patient with mutilated dentition was treated to an acceptable result with the help of mini-implants for anchorage, autotransplantation of 2 teeth, one dental implant, and multiple prostheses. The major problems for this mutilated dentition were multiple missing teeth, bite collapse with posterior crossbites, deepbite with a canted gummy smile, and severe skeletal discrepancy of maxillary protrusion and mandibular retrusion. Mini-implant anchorage was applied to retract and intrude the maxillary arch to reduce the protrusion and rotate the mandible counterclockwise to improve the chin projection. Two autotransplantations, one dental implant, and multiple prostheses were used to accomplish a satisfactory full mouth rehabilitation with an interdisciplinary approach, including orthodontics, periodontics, endodontics, prosthodontics, and implantology. The understanding of biological principles, improvement in surgical protocol makes it possible to preserve the periodontal ligament (PDL) cells with atraumatic extraction after loosening the donor with orthodontic force and reduce the extraoral time with the 3-dimensional print-out replica segmented from cone-beam computed tomography for trying fitness. Soft wire splinting to gain initial stabilization and root canal treatment to avoid endotoxin further reduce the risk of root resorption, loss of attachment, and ankylosis. Autotransplantation could be considered as a part of full mouth rehabilitation. Orthodontic space management is also an important procedure to confirm the site of dental implant installation in the interdisciplinary collaboration., (Copyright © 2021 American Association of Orthodontists. Published by Elsevier Inc. All rights reserved.)

Introduction: The purpose of this study was to analyze the treatment effects after molar distalization using modified C-palatal plates with and without second molar eruption and to evaluate the three-dimensional position of the molars during long-term retention using cone-beam computed tomography., Methods: The study sample comprised 74 third molars in 42 patients. Twenty-seven adolescent patients (mean age, 12.6 years) having 48 maxillary third molars were divided into 2 groups according to the eruption of their second molars: 15 patients with second molar eruption (group 1) and 12 patients without second molar eruption (group 2). Pretreatment, posttreatment, and long-term data (mean, 5.2 years) from cone-beam computed tomography were scanned and compared with control groups., Results: There was less tipping movement of the first and second molars (0.94° and 3.22°) and distal tipping movement of the third molars (8.91°) in group 1 than in group 2 (4.36°, 7.39°, and 3.08°, respectively), but the treatment time was shorter and the positional change of the third molars was insignificant in group 2. In the long-term, the second molars fully erupted after distalization in group 2, and there was no difference in the third molar position between group 1, group 2, and the control group, except for the vertical position of the third molars in group 1., Conclusions: In the long-term, the second molars fully erupted after distalization, and the third molars were in a favorable position. Therefore, these findings suggest that clinicians do not need to extract developing third molars before distalization in adolescents., (Copyright © 2021 American Association of Orthodontists. Published by Elsevier Inc. All rights reserved.)

Background: Several treatment approaches can be found in the literature about early treatment of open bite. However, no studies have addressed the use of a removable posterior bite plane with a tongue crib (RPBP/C), compared with functional appliances, for treating open-bite cases. The objectives of this trial was to compare the effectiveness of the open-bite Bionator (OBB) and the RPBP/C as an early intervention to correct skeletal open-bite cases in children, in terms of limiting excessive vertical growth of the craniofacial skeletal components and normalizing the developement of the anterior dentoalveolar region., Materials and Methods: Two-arm, parallel-group randomized controlled trial was conducted. Forty patients with a skeletal anterior open bite (age range: 7.5-10.5 years) were treated at the University of xxxx School of Dentistry in xxxx, xxxx. They were distributed randomly into 2 equal groups: the OBB group (20 patients; mean age: 8.8 ± 1.5 years) and the RPBP/C group (20 patients; mean age: 8.6 ± 1.1 years). Randomization was based on a computer-generated sequence of random numbers. Primary outcome measures were the skeletal and dentoalveolar variables, whereas the secondary outcome measures were the soft-tissue parameters assessed on standardized lateral cephalograms collected before and after 12 months of treatment. Mann-Whitney U tests were used to detect significant differences between the 2 groups., Results: Both the OBB and the RPBP/C appliances induced favorable dental effects. A statistically significant difference was found between the 2 groups in the overbite (P = 0.003). Open bite in the OBB group showed a mean closure of 4.91 mm (SD 0.4 mm), and a mean closure of 3.43 mm (SD 0.3 mm) was observed in the RPBP/C group. Dentoalveolar changes at the anterior region were evident, with statistically significant extrusion, and lingual tipping of the maxillary and mandibular incisors (P ≤ 0.05). The results showed no significant differences in the skeletal changes between the 2 groups., Conclusions: The OBB and the upper posterior bite plane with crib were both effective in the early treatment of the skeletal anterior open bite. However, closure of the anterior open bite was mainly due to the dentoalveolar changes at the anterior region of the dental arches., (Copyright © 2021 Elsevier Ltd. All rights reserved.)

Introduction: The objective of this study was to compare the aging changes of the dental arches in orthodontically treated and untreated subjects after a 4-decade follow-up period., Methods: This retrospective study analyzed 2 groups. The treated group comprised 29 patients (11 male, 18 female) presenting with Class I or Class II malocclusions orthodontically treated with extractions of 4 first premolars. Dental models taken at pretreatment (12.84 years), posttreatment (14.95 years), and long-term posttreatment (51.37 years) were evaluated. The untreated (control) group consisted of 22 untreated patients with dental models taken at 13.32, 17.82, and 60.95 years of age. The dental models were digitized, and the following variables were evaluated: Little irregularity index, intercanine, interpremolar and intermolar widths, arch length, arch perimeter, overjet, and overbite. Interphase comparison of the treated group was performed with repeated measures analysis of variance and Tukey tests. Intergroup comparisons were performed using t tests (P <0.05)., Results: Crowding was corrected with treatment but relapsed significantly in the long term. Intercanine width increased with treatment and decreased in the long term. Interpremolar and intermolar widths, arch perimeter, and length decreased with treatment and continued to decrease long-term posttreatment. Overjet and overbite were corrected with treatment and remained stable in the long term. From posttreatment to long-term posttreatment, a greater crowding increase was observed in the treated group than in the untreated group. The treated group demonstrated a greater decrease in mandibular intercanine and maxillary and mandibular interpremolar widths than the untreated sample. Overbite increased in the treated group and decreased in the untreated group. The multiple regression analysis showed that previous 4-premolar extractions orthodontic treatment is significantly associated with anterior crowding in the long term., Conclusions: In the long-term, the treated patients showed relapse of crowding and a decrease in arch form. Long-term changes of treated patients were different from untreated subjects. Relapse might have contributed to greater changes in incisor crowding and arch widths observed in the treated patients., (Copyright © 2021 American Association of Orthodontists. Published by Elsevier Inc. All rights reserved.)

Introduction: Control of overbite is considered essential in achieving ideal orthodontic outcomes. Questions have been raised regarding the accuracy of ClinCheck software (Align Technology, Santa Clara, Calif) in predicting posttreatment outcomes with Invisalign, with the paucity of well-researched literature available on this topic. This research aimed to investigate and determine the accuracy of Invisalign (Align Technology) in correcting a deep overbite by comparing the outcomes predicted by ClinCheck with achieved posttreatment outcomes., Methods: A retrospective study was conducted using pretreatment and posttreatment intraoral scans and predicted outcome (ClinCheck) stereolithography files of 42 adult patients consecutively treated with Invisalign from January 2014 and completed before July 2018, selected from the files of 1 experienced orthodontist. Patients included in the study were treated without extractions and with a minimum of 14 dual arch Invisalign aligners using a 2-weekly aligner change protocol. The pretreatment, posttreatment, and predicted outcome stereolithography files for each patient were imported into Geomagic Control X (3D Systems, Rock Hill, SC) software to measure overbite., Results: The deeper the patient's initial overbite and the greater the amount of programmed reduction in overbite according to ClinCheck, the greater the discrepancy in overbite expression posttreatment. ClinCheck over-predicted overbite reduction in 95.3% of patients in which, on average, only 39.2% of the prescribed overbite reduction was expressed., Conclusions: Overbite reduction may result in suboptimal outcomes when using the Invisalign appliance unless remedial measures are employed. The deeper the initial overbite, the more challenging it is to achieve the prescribed posttreatment overbite., (Copyright © 2021 American Association of Orthodontists. Published by Elsevier Inc. All rights reserved.)

A 28-year-old woman desired orthodontic retreatment for lip protrusion and excessive gingival display in both the anterior and posterior areas on full smiling. She had previously undergone an extraction orthodontic treatment for correction of open bite. She was diagnosed with skeletal Class Ⅱ hyperdivergence. To mimic LeFort Ⅰ maxillary impaction surgery, posterosuperior movement of the maxillary whole dentition was planned, and bodily distalization of both the maxillary and the mandibular whole dentitions to improve lip protrusion. A combination of lingual appliances, 2 appropriately fabricated power arms, and 1 midpalatal microimplant contributed to the posterosuperior intrusion and bodily distalization of the maxillary arch. With the use of lingual appliances, 2 lever arms, and 2 conventional microimplants, the mandibular arch was bodily distalized. The active treatment period was 37 months, and the results were stable 12 months after treatment., (Copyright © 2021 American Association of Orthodontists. Published by Elsevier Inc. All rights reserved.)

Introduction: Extreme patterns of vertical facial divergence are of great importance to clinicians because of their association with dental malocclusion and functional problems of the orofacial complex. Understanding the growth patterns associated with vertical facial divergence is critical for clinicians to provide optimal treatment. This study evaluates and compares growth patterns from childhood to adulthood among 3 classifications of vertical facial divergence using longitudinal, lateral cephalograms from the Craniofacial Growth Consortium Study., Methods: Participants (183 females, 188 males) were classified into 1 of 3 facial types on the basis of their adult mandibular plane angle (MPA): hyperdivergent (MPA >39°; n = 40), normodivergent (28° ≤ MPA ≤ 39°; n = 216), and hypodivergent (MPA <28°; n = 115). Each individual had 5 cephalograms between ages 6 and 20 years. A set of 36 cephalometric landmarks were digitized on each cephalogram. Landmark configurations were superimposed to align 5 homologous landmarks of the anterior cranial base and scaled to unit centroid size. Growth trajectories were calculated using multivariate regression for each facial type and sex combination., Results: Divergent growth trajectories were identified among facial types, finding more similarities in normodivergent and hypodivergent growth patterns than either share with the hyperdivergent group. Through the use of geometric morphometric methods, new patterns of facial growth related to vertical facial divergence were identified. Hyperdivergent growth exhibits a downward rotation of the maxillomandibular complex relative to the anterior cranial base, in addition to the increased relative growth of the lower anterior face. Conversely, normodivergent and hypodivergent groups exhibit stable positioning of the maxilla relative to the anterior cranial base, with the forward rotation of the mandible. Furthermore, the hyperdivergent maxilla and mandible become relatively shorter and posteriorly positioned with age compared with the other groups., Conclusions: This study demonstrates how hyperdivergent growth, particularly restricted growth and positioning of the maxilla, results in a higher potential risk for Class II malocclusion. Future work will investigate growth patterns within each classification of facial divergence., (Copyright © 2021 American Association of Orthodontists. Published by Elsevier Inc. All rights reserved.)

Background: Even though treatment of Class II malocclusion with premolar extractions and incisor retraction might affect incisor inclination and soft tissue profile, the effects of bracket prescription on this have not been thoroughly assessed., Methods: Fifty patients (mean age: 13.6 years; 34% male) receiving extraction-based treatment with either standard Edgewise or pre-adjusted appliances were included. Between-group differences in the incisor inclination assessed with lateral cephalograms were analyzed statistically with linear/logistic regression at 5%., Results: Treatment-induced changes included retroclination of the upper/lower incisors (-3.0° and -2.0°, respectively), retraction of the upper/lower incisors (-3.4 mm and -1.5 mm, respectively), retraction of the upper/lower lip (-2.1 mm and -2.0 mm, respectively), and enlargement of the nasolabial angle (+1.6°). Analysis of the data adjusting for confounders indicated that the pre-adjusted group, after treatment, had larger inclination of the upper or lower incisors (+3.2° and +4.5°, respectively), more prominent upper incisors relative to the facial plane (+1.3 mm), and smaller interincisal angle (-7.3 or -7.7°). Post-treatment upper incisor inclination fell within the cephalometric norm significantly more in the pre-adjusted than in the standard Edgewise group (odds ratio 4.3; 95% confidence interval 1.1-16.6). No differences were found in lower incisor prominence, upper/lower lip prominence, or nasolabial angle., Conclusions: Pre-adjusted appliances were associated with increased inclination of the upper and lower incisors, with more prominent upper incisors, and with more acute interincisal angle after retraction compared with standard Edgewise appliances. However, such differences did not translate in greater retraction of the upper/lower lips and greater nasolabial angle., (Copyright © 2021 The Authors. Published by Elsevier Inc. All rights reserved.)

Introduction: This research aimed to compare treatment effects of functional appliances between children with and without morphologic deviations in the upper spine and analyze associations between Atlas dimensions and the short- and long-term treatment effects., Methods: Sixty-eight prepubertal or pubertal children (35 boys and 33 girls; mean age, 11.47 ± 1.39 years) treated with Class II functional appliances were included. Lateral cephalograms were taken at pretreatment (T1), postfunctional appliance treatment (T2), and after retention at postpuberty (T3). Upper spine morphology and Atlas dimensions were evaluated at T1. T1-T2 and T1-T3 lateral cephalograms were superimposed using a structural method. Changes in the jaws were compared with multiple linear regression analysis between children with and without deviations in the upper spine. Associations between the changes and Atlas dimensions were analyzed by partial correlation., Results: Children with morphologic deviations in the upper spine showed significantly more backward rotation of the mandible (P <0.01) and increased inclination of the jaws (P <0.05, P <0.01) from T1-T2 and significantly smaller condylar growth (P <0.01) from T1-T3 compared with children without the deviations. Atlas height was significantly associated with vertical and rotational changes in the mandible (P <0.01) from T1-T2 and condylar growth (P <0.05) from T1-T2 and T1-T3., Conclusions: Morphologic deviations in the upper spine and low Atlas height were significantly associated with smaller condylar growth induced by functional appliances in the long term. Upper spine morphology and the Atlas dimension may be valuable in phenotypic differentiation in children with Class II malocclusion for optimal treatment outcome., (Copyright © 2021 American Association of Orthodontists. Published by Elsevier Inc. All rights reserved.)

Background: Open bite is considered one of the most complicated malocclusions in orthodontic treatment. In this study, the authors successfully treated total open bite involved in hypercementosis using orthodontic miniscrews., Case Description: A woman aged 25 years 8 months had total open bite. Her occlusal contact at the maximum intercuspation was present at the right second molars. A panoramic radiograph showed diffuse hypercementosis. The titanium miniscrews were interradicullay implanted between the first and second molars, and intrusion force was applied for 14 months. After active treatment, the patient's maxillary first molars showed about 1.6-millimeters of intrusion, resulting in counterclockwise mandibular rotation. Her acceptable occlusion was maintained after 1.0-year retention., Practical Implications: Miniscrews might be useful tool to improve malocclusion involved in diffuse hypercementosis though they are considered to be difficult to move and brought on ankylosis., (Copyright © 2021 American Dental Association. Published by Elsevier Inc. All rights reserved.)

Introduction: This single-center 2-arm parallel randomized clinical trial aimed to compare the dentoskeletal effects of bonded spurs combined with posterior build-ups vs conventional bonded spurs in the treatment of anterior open bite malocclusion in the mixed dentition., Methods: Patients aged from 7 to 11 years with anterior open bite, recruited at a university orthodontic clinic, were randomly allocated into 2 groups. The experimental group consisted of patients treated with bonded spurs combined with posterior build-ups. The comparison group comprised patients treated with conventional bonded spurs. Lateral headfilms were obtained at pretreatment and after 12 months of treatment. The primary outcome was the change in the overbite. Randomization was performed using the Web site www.randomization.com. Sequentially numbered opaque and sealed envelopes were used for allocation concealment. Blinding was applicable for outcome assessment only. Intergroup comparisons were performed using t or Mann-Whitney U tests (P <0.05). Mean difference (MD) and 95% confidence interval (CI) were obtained., Results: The experimental group included 24 patients (17 female, 7 male; mean age, 8.22 ± 1.06 years) and the comparison group comprised 25 patients (14 female, 11 male; mean age, 8.30 ± 0.99 years). Baseline demographic and cephalometric characteristics were similar between groups. After 12 months, all patients showed improvements. Both groups showed similar improvements of the overbite (MD, 0.00 mm; 95% CI, -0.92 to 0.91), similar slight decreases of the gonial (MD, 0.02°; 95% CI, -1.11 to 1.15) and mandibular plane (MD, 0.15°; 95% CI, -0.64 to 0.93) angles, and similar mandibular molar extrusion (MD, 0.14 mm; 95% CI, -0.27 to 0.56). The experimental group showed significantly smaller extrusion of the maxillary first molar than the comparison group (MD, -0.70 mm; 95% CI, -0.92 to -0.49). The other dentoskeletal variables showed similar changes without statistically significant intergroup differences. No serious harm was observed other than plaque accumulation around the spurs., Conclusions: Similar overbite increases and dentoskeletal changes were observed in both groups after 12 months of treatment. Although the experimental group showed significantly smaller extrusion of the maxillary molars, no greater counterclockwise rotation of the mandible than the comparison group was observed., Registration: This trial was registered at Clinicaltrials.gov (Identifier NCT03702881)., Protocol: The protocol was not published., Funding: This trial was financed in part by the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - Brasil (CAPES), Finance Code 001; and by grants: no. 2017/06440-3, no. 2018/05238-9 and no. 2018/24003-2, São Paulo Research Foundation (FAPESP)., (Copyright © 2020 American Association of Orthodontists. Published by Elsevier Inc. All rights reserved.)

Introduction: Anterior open bite (AOB) continues to be a challenging malocclusion for orthodontists to treat and retain long-term. There is no consensus on which treatment modality is most successful. This study reports on the overall success rate of AOB orthodontic treatment in the adult population across the United States, as well as 4 major treatment modalities and other factors that may influence treatment success., Methods: Practitioners and their adult patients with AOB were recruited through the National Dental Practice-Based Research Network. Patient dentofacial and demographic characteristics, practitioner demographic and practice characteristics, and factors relating to orthodontic treatment were reported. Treatment success was determined from posttreatment (T2) lateral cephalometric films and intraoral frontal photographs. Treatment was categorized into 4 main groups: aligners, fixed appliances, temporary anchorage devices (TADs), and orthognathic surgery. Extractions were also evaluated. Bivariate and multivariable models were used to investigate the association between treatment success and treatment modality, pretreatment (T1) dentofacial characteristics, patient and practitioner demographics, and practice characteristics, adjusting for clustering of patients within practice., Results: A total of 254 patients, enrolled by 84 practitioners, contributed to T2 data for this study. There were 29 patients in the aligner group, 152 in fixed appliances, 20 in TADs, and 53 in surgery. A total of 49 patients underwent extractions of teeth other than third molars. Ninety-three percent finished treatment with a positive overbite on the T2 lateral cephalogram, and 84% finished with a positive vertical overlap of all incisors. The small number of aligners and TAD patients limited the ability to compare success rates in these groups. Patients treated with orthognathic surgery had a higher rate of success compared with those treated with fixed appliances only. Treatment success was also associated with academic practice setting, T1 mandibular plane angle ≤30°, no to mild T1 crowding, and treatment duration <30 months., Conclusions: The overall success of orthodontic treatment in adult patients with AOB who participated in this study was very high. Orthognathic surgery was the only treatment modality that exhibited a statistically higher odds of successful outcomes. Some T1 dentofacial characteristics and treatment factors were associated with the successful closure of AOB., (Copyright © 2020 American Association of Orthodontists. Published by Elsevier Inc. All rights reserved.)

Introduction: This study aimed to investigate dentofacial changes in patients treated with maxillary molar intrusion with zygomatic anchors., Methods: The study group was composed of 19 patients with anterior open bite who had intrusion of the posterior dentoalveolar segment using an acrylic appliance supported by bilateral zygomatic miniplates. The study was carried out on lateral cephalograms of the subjects taken before treatment and after intrusion., Results: Cephalometric changes obtained with maxillary molar intrusion were statistically significant. ANB, Wits, SN-GoGn, PP-MP, ANS-Me, NA-APo, SN-OP, U1-OP, U6-NF, overjet, and overbite values were also statistically significant., Conclusions: Posterior dentoalveolar intrusion by zygomatic anchorage was an effective method for anterior open bite treatment. Although overbite and vertical skeletal measurements changed because of posterior dentoalveolar intrusion, the soft tissue was not significantly affected., (Copyright © 2020. Published by Elsevier Inc.)

Introduction: This study aimed to evaluate the stability of transverse changes after Class II malocclusion correction with the pendulum fixed distalizer, followed by preadjusted edgewise fixed orthodontic appliances., Methods: This longitudinal study was conducted in the maxillary dental casts of 20 Class II malocclusion subjects (mean age, 12.5 years; 14 females and 6 males). Eighty 3-dimensional maxillary dental casts were analyzed; 20 at the beginning of treatment, 20 after distalization, 20 after edgewise appliance debonding, and 20 at 5 years posttreatment. Maxillary transverse distances between canines, first premolars, second premolars, first molars, and second molars were analyzed using Geomagic Studio 5 (3D Systems, Rock Hill, SC)., Results: There were no significant changes in intercanine distance during and after treatment. There were significant interfirst and intersecond premolar distance increases during treatment. There were significant interfirst and intersecond molar distance increases during the distalization phase. However, there were significant decreases in these distances at the end of treatment. There were no significant long-term posttreatment changes., Conclusions: The intercanine distance remains stable during and after treatment. The interfirst and intersecond premolar distances significantly increase during treatment and remain stable after treatment. The interfirst and intersecond molar distances increase during the distalization phase, decrease at the end of treatment, and remain stable after treatment., (Copyright © 2020 American Association of Orthodontists. Published by Elsevier Inc. All rights reserved.)

Introduction: This retrospective study aimed to assess the stability of Class II malocclusion treatment with the distal jet, followed by fixed appliances., Methods: Seventy-five cephalograms of 30 subjects were divided into 2 groups. The treated group consisted of 15 patients who were evaluated at the pretreatment, posttreatment, and long-term posttreatment stages. The control group consisted of 15 subjects with normal occlusion, comparable to the experimental group at the long-term posttreatment period. Intergroup comparison of posttreatment changes was evaluated with t tests., Results: In the long-term posttreatment period, there was no significant change in the anteroposterior position of the maxilla and mandible to the cranial base. The lower anterior face height had a significantly smaller increase in the treated than in the control group. The maxillary molars in the treated group had significantly smaller vertical development, and the mandibular incisors had significantly greater labial tipping and protrusion than the control group. The treatment produced significant improvement in molar relationship and reduction of overbite and overjet, which remained stable in the long-term posttreatment period. There was greater upper lip protrusion in the experimental than in the control group in the long-term posttreatment period., Conclusions: Treatment of Class II malocclusions with the distal jet, followed by fixed appliances, showed good long-term stability in molar relationship, overbite, and overjet., (Copyright © 2020 American Association of Orthodontists. Published by Elsevier Inc. All rights reserved.)

A gummy smile is one of the most problematic characteristics in patients with a Class II Division 2 malocclusion, and the correction of vertical position and incisor torque is often challenging for the orthodontist. This case report describes the orthodontic treatment of a 31-year-old woman, assisted by miniscrew mechanics for maxillary arch distalization and correction of a gummy smile with a brachyfacial pattern. Two different mechanics were used. Miniscrews were placed in both maxillary tuberosities, and the maxillary arch was successfully distalized, correcting the Class II relationship. Interradicular miniscrews were placed for maxillary and mandibular incisor intrusion to correct the gummy smile, overbite, and torque. Finally, periodontal surgery was performed to lengthen the maxillary incisor crowns. Satisfactory smile esthetics and good occlusion were achieved. Follow-up after 24 months confirmed that the outcome was stable., (Copyright © 2020 American Association of Orthodontists. Published by Elsevier Inc. All rights reserved.)

Treatment for a patient with a dental anomaly pattern is challenging and complex. This article presents a rare case with an association of multiple ectopic eruptions treated in 2 phases. An 8-year-old boy in the early mixed dentition showed a Class II, Division 2 malocclusion, and an ectopic eruption of the mandibular right lateral incisor. The treatment plan included extractions of the deciduous mandibular right lateral incisor and canine, followed by partial mandibular fixed appliances and a lingual arch. In the late mixed dentition, the panoramic radiograph showed bilateral ectopic eruptions of the maxillary canines. The deciduous maxillary canines were extracted, and a cervical headgear was installed. Within 12 months, both permanent maxillary canines spontaneously erupted. Comprehensive orthodontic treatment was initiated when the patient was aged 13 years to level the curve of Spee and reduce the overbite. Phase 2 lasted 15 months. In patients with dental anomaly patterns, longitudinal follow-up during the mixed dentition is highly important and might contribute to simplifying comprehensive orthodontic treatment and reducing complications and adverse effects., (Copyright © 2020 American Association of Orthodontists. Published by Elsevier Inc. All rights reserved.)

Introduction: Although functional appliances (FAs) are primarily used to treat Class II malocclusions, their effects on the upper airway have generally been reported in studies involving 2-dimensional analysis of cephalometric radiographs. This study aimed to use 3-dimensional cone-beam computed tomography to (1) determine the effects on upper airway volume and minimum cross-sectional area (MCA) when an FA is used for orthodontic treatment and (2) identify pretreatment markers for airway changes., Methods: Pre- and posttreatment cone-beam computed tomography scans were selected from 73 children whose orthodontic treatment involved using a fixed FA (37 girls and 36 boys; mean age 12.0 years); a control group was constituted and included the scans of 73 children who were matched for chronological age, skeletal age, sex, and mandibular inclination and who received orthodontic treatment for minor malocclusions without an FA. Changes in upper airway volume and MCA were evaluated by a standardized, previously validated method analyzed with mixed-effects linear regression., Results: Upper airway volume and MCA increased over time for both the FA and the matched control groups (P <0.05). The FA caused an additional significant increase in upper airway volume and MCA (P <0.0001) when compared with the control group. An increased ANB angle, a reduced mandibular inclination, and a reduced skeletal age pretreatment had a positive effect on upper airway volume and MCA (P <0.05)., Conclusions: A fixed FA was associated with a significant increase in upper airway volume and MCA in children when compared with controls. Pretreatment ANB angle, skeletal age, and mandibular inclination may be predictors for positive changes in the upper airway. The results may prove valuable in treating children with Class II malocclusions with compromised upper airways., (Copyright © 2020 American Association of Orthodontists. All rights reserved.)

Dental health and patient satisfaction at the end of orthodontic treatment are needed if the treatment is to be considered successful. This case report highlights the importance of proper diagnosis for a patient initially treated with camouflage, despite the indications for surgery. A 16-year-old male patient sought treatment complaining about his appearance. He had been using an appliance for 6 years without improvement. He had a convex profile, an enlarged lower third of the face, reduced cervical-mandibular line, and Class II molar relationship. The maxillary incisors had excessive buccal root torque, throbbing pain, and dental mobility, with no visible bone coverage in the tomographic sections. The cephalometric analysis confirmed the skeletal Class II relationship (ANB, 11.6°; Wits appraisal, 14.2 mm) because of severe mandibular deficiency (SNB, 71.2°), aggravated by the vertical growth tendency (FMA, 27.3°). Changes in IMPA (108.1°) and U1-NA (0.9°; -2.9 mm) reflected the previous orthodontic attempt to compensate for the malocclusion. After periodontal and endodontic evaluation, a new treatment plan was developed. The incisors would be positioned in their bone bases, the mandibular first premolars would be extracted to create space for the second molars and increase the overjet, and the patient would be referred for orthognathic surgery. The patient was satisfied with the esthetic and functional results of this treatment., (Copyright © 2020 American Association of Orthodontists. Published by Elsevier Inc. All rights reserved.)

Introduction: The objective of this research was to compare the 2 treatment protocols including a functional mandibular advancer (FMA; Forestadent, Pforzheim, Germany) followed by multibracket appliances (MBAs) vs a Forsus device (3M Unitek, Monrovia, Calif) in combination with MBA concerning treatment outcomes and posttreatment stability., Methods: This study was conducted using lateral cephalograms of patients who were treated with MBA, which was used either after an FMA or concurrently with a Forsus device, and of patients who had untreated Class II malocclusion (control group). Each group consisted of 19 subjects in cervical stage 2 or cervical stage 3 stages according to the cervical vertebral maturation index. Cephalograms were taken for the treated groups at T1 (pretreatment), T2 (completion of the MBA treatment), and T3 (at least 2 years after T2)., Results: Significant intergroup differences at the T1-T2 period were observed in favor of the FMA concerning mandibular advancement, intermaxillary relationship, and mandibular elongation. With Forsus treatment, restrained maxillary growth and a slightly improved intermaxillary relationship rebounded after treatment (P <0.05). At the end of treatment, mandibular incisor protrusion and occlusal plane rotation were greater in the Forsus group than in the FMA group (P <0.05), and maxillary incisor retroclination was significant in the Forsus group. During the posttreatment period, although no significant changes were present in the incisors' inclination, relapses of the T1-T2 improvements in overjet and overbite and the recidive of the occlusal plane rotation were significantly higher in the Forsus group., Conclusions: Treatment protocol including an FMA was found to be more effective with mandibular skeletal effects and was more stable with a lesser degree of relapse in overjet and overbite than the Forsus protocol., (Copyright © 2020 American Association of Orthodontists. Published by Elsevier Inc. All rights reserved.)

Introduction: This study aimed to evaluate the effects of the Forsus fatigue-resistant device (FRD) EZ2 appliance (3M Unitek, Monrovia, Calif) on facial soft tissues by using images obtained from cephalometric radiographs and 3-dimensional (3D) facial scanning system., Methods: A total of 20 patients treated with the Forsus FRD EZ2 appliance were included in this study. The cervical vertebral maturation index was used to determine growth and development stages, and the subjects were investigated at cervical vertebral maturation stages 5 and 6 (ie, postpeak period). Three-dimensional facial scanning images were obtained with 3dMD Face (3dMD Ltd, Atlanta, Ga). Cephalometric radiographic images were taken before placement of the appliance (T0), immediately after removal (T1), and at the 6-month (T2) follow-up after the removal of the appliance. For comparison of the data, one-way repeated-measures analysis of variance and paired t test were used at P < 0.05., Results: Statistically significant changes were found in the Wits value, IMPA, L1P-NB (°), L1-NB (mm), L1P-APog, U1P-L1P, overjet, overbite, Ls-E, and labiomental angle in T0-T1. In T0-T2, statistically significant changes in the Wits, IMPA, L1P-NB (°), overjet, overbite and Ls-E values were observed., Conclusions: The results revealed that the correction of malocclusion with Forsus FRD EZ2 appliance in patients at the postpeak period was mainly dentoalveolar. The soft tissues were affected to a limited extent. Three-dimensional facial scanning demonstrated similar accuracy and precision to traditional cephalometry, being a repeatable and accurate tool for linear and surface measurements., (Copyright © 2020 American Association of Orthodontists. Published by Elsevier Inc. All rights reserved.)

Introduction: This study aimed to evaluate whether viewing digital treatment simulations influenced orthodontic treatment planning decisions or practitioners' confidence in their selected plans., Methods: Records of 6 patients representing different case types (eg, missing teeth, crowding, sagittal discrepancies) were collected. A total of 22 orthodontists and 7 orthodontic residents viewed these records and formulated treatment plans for each case, indicating their most recommended plan and up to 2 alternative plans. After treatment planning each case, digital setups of each treatment plan indicated by the practitioner were shown. The practitioners were then asked if they still recommended their original plan, or if they would now recommend a different plan. Their confidence levels in the success of their plans were recorded before and after viewing the setups., Results: After viewing the digital setups, there was a significant change in the treatment plan for 9.2% of the cases. These included modifications like changing the extraction pattern or proposing space closure rather than opening space for an implant. In an additional 14.4% of the cases, treatment plans underwent partial changes, like adding interproximal reduction or temporary anchorage devices. Practitioner confidence levels increased after viewing the setups. In cases where the treatment plan changed, the practitioner's confidence level in the plan increased the most, and the final confidence level was uniformly high among all practitioners. Practitioners reported the most helpful features of digital setups were the ability to superimpose the setup with the original model, determine the amount of tooth movement needed, check the final incisal relationship (overjet and overbite), and establish the amount of interproximal reduction required., Conclusions: Viewing digital setups resulted in changes to the treatment plans in about 24% of the cases. The use of digital setups was associated with higher levels of confidence in the selected plans., (Copyright © 2019 American Association of Orthodontists. Published by Elsevier Inc. All rights reserved.)

This case report describes the successful extraction treatment of a Class II malocclusion with excessive maxillary sinus pneumatization. A 20-year-old man sought treatment with the major complaint of protrusive mouth and anterior teeth. He was diagnosed with a skeletal Class II relationship and protrusion of the maxilla. The clinical examination showed a severe Class II molar relationship with excessive overjet and deep overbite. Panoramic radiograph showed obvious maxillary sinus pneumatization bilaterally. Three premolars and one deciduous molar were extracted, and spaces were used to correct molar relationship and retract maxillary incisors. Light forces and low speed movement were applied to overcome the challenge of moving teeth through the maxillary sinus wall. Balanced facial esthetic and stable occlusion were obtained posttreatment with a notable bone formation of the maxillary sinus wall. This result highlights the possibility of tooth movement through cortical floor with bone remodeling and no obvious complications., (Copyright © 2019 American Association of Orthodontists. Published by Elsevier Inc. All rights reserved.)