1. A novel clinical risk scoring system for neurodevelopmental outcomes among survivors of neonatal hypoxic-ischemic encephalopathy (HIE)
- Author
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Theresa Estiphan, Julie Sturza, Renée A. Shellhaas, and Martha D. Carlson
- Subjects
Electroencephalography (EEG) ,Hypoxic-ischemic encephalopathy (HIE) ,Magnetic resonance imaging (MRI) ,Neonate ,Neurodevelopment ,Prognosis ,Pediatrics ,RJ1-570 - Abstract
Objective: We aimed to develop a risk scoring system as a predictor of 24-month neurodevelopmental outcomes (cognitive, language, and motor) for neonates treated with therapeutic hypothermia for hypoxic-ischemic encephalopathy (HIE). Methods: This was a chart review of infants with HIE treated with therapeutic hypothermia who were admitted to the Neonatal Intensive Care Unit (NICU) at the University of Michigan between 2009 and 2019 and followed in the neonatal developmental clinic until 24 months of age. We examined bivariate associations between the neonatal characteristics and Bayley-III scores. We then performed stepwise logistic regression. To create the risk scores, a participant was given one point for each of the factors included in the final model. Results: Fifty-five infants were included. The final model for Bayley cognitive abnormality included abnormal neonatal neurologic exam (p
- Published
- 2024
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