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2 results on '"Morotti D."'

1. Evidence of vertical transmission of SARS-CoV-2 and interstitial pneumonia in second-trimester twin stillbirth in asymptomatic woman. Case report and review of the literature

Author

Patane, L, Cadamuro, M, Massazza, G, Pirola, S, Stagnati, V, Comerio, C, Carnelli, M, Arosio, M, Callegaro, A, Tebaldi, P, Rigoli, E, Gianatti, A, Morotti, D, Callegaro, AP, Patane, L, Cadamuro, M, Massazza, G, Pirola, S, Stagnati, V, Comerio, C, Carnelli, M, Arosio, M, Callegaro, A, Tebaldi, P, Rigoli, E, Gianatti, A, Morotti, D, and Callegaro, AP

Abstract

Data on the vertical transmission rate of COVID-19 in pregnancy are limited, although data reporting mother-fetal transmission in the second trimester of pregnancy are controversial. We described a case of second-trimester twin stillbirth in a woman with SARS-CoV-2 infection in which placental and fetal markers of infection were detected, despite the absence of respiratory syndrome. The patient developed clinical chorioamnionitis and spontaneously delivered 2 stillborn infants. Placental histology and immunohistochemistry demonstrated SARS-CoV-2 infection mostly within the syncytiotrophoblast, and fetal autopsy showed the development of interstitial pneumonia. Our findings demonstrated that in utero vertical transmission is possible in asymptomatic pregnant women with SARS-CoV-2 infection and that infection can lead to severe morbidity in the second trimester of pregnancy.

Published
2022

2. Intestinal ischemia in the COVID-19 era.

Author

Norsa L, Valle C, Morotti D, Bonaffini PA, Indriolo A, and Sonzogni A

Subjects
Betacoronavirus metabolism, COVID-19, COVID-19 Testing, Clinical Laboratory Techniques, Coronavirus Infections complications, Coronavirus Infections pathology, Endarteritis etiology, Endarteritis pathology, Fatal Outcome, Humans, Infarction etiology, Infarction pathology, Infarction surgery, Intestinal Mucosa virology, Intestine, Small metabolism, Intestine, Small surgery, Male, Mesenteric Ischemia etiology, Mesenteric Ischemia pathology, Mesenteric Ischemia surgery, Middle Aged, Pandemics, Pneumonia, Viral complications, Pneumonia, Viral pathology, RNA, Messenger metabolism, SARS-CoV-2, Shock, Septic etiology, Spike Glycoprotein, Coronavirus genetics, Thrombosis etiology, Thrombosis pathology, Tomography, X-Ray Computed, Betacoronavirus genetics, Coronavirus Infections diagnosis, Infarction diagnosis, Intestinal Mucosa metabolism, Intestine, Small blood supply, Mesenteric Ischemia diagnosis, Pneumonia, Viral diagnosis
Abstract

Competing Interests: Declaration of Computing Interest Authors declares no conflict of interest and no financial support for this study.

Published
2020
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