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1. Phase I and pharmacological study of increased dose oral topotecan in combination with intravenous cisplatin.

Author

Gelderblom AJ, Loos WJ, de Jonge MJ, Sparreboom A, Planting AS, van der Burg ME, Brouwer E, Verheij C, Ouwens L, Hearn S, and Verweij J

Subjects
Administration, Oral, Adult, Aged, Antineoplastic Combined Chemotherapy Protocols pharmacokinetics, Cisplatin administration & dosage, Cisplatin adverse effects, Cisplatin pharmacokinetics, Female, Humans, Infusions, Intravenous, Male, Middle Aged, Neoplasms metabolism, Topotecan administration & dosage, Topotecan adverse effects, Topotecan pharmacokinetics, Antineoplastic Combined Chemotherapy Protocols administration & dosage, Neoplasms drug therapy
Published
2000
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