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43 results on '"Scd1"'

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1. Dose-dependent effects of hydroquinone on liver injury and lipid dysregulation based on SCD1/AMPK signaling pathway in C57BL/6 mice

2. REV-ERBα inhibitor rescues MPTP/MPP+-induced ferroptosis of dopaminergic neuron through regulating FASN/SCD1 signaling pathway

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3. Scd1 and monounsaturated lipids are required for autophagy and survival of adipocytes

4. A Scd1-mediated metabolic alteration participates in liver responses to low-dose bavachin

5. A novel insight into the key gene signature associated with the immune landscape in the progression of sarcopenia

6. Novel biomarker in hepatocellular carcinoma: Stearoyl-CoA desaturase 1.

7. Inhibition of stearoyl-CoA desaturase 1 in the mouse impairs pancreatic islet morphogenesis and promotes loss of β-cell identity and α-cell expansion in the mature pancreas

8. Aspirin promotes RSL3-induced ferroptosis by suppressing mTOR/SREBP-1/SCD1-mediated lipogenesis in PIK3CA-mutatnt colorectal cancer

9. Dysregulated lipid metabolism blunts the sensitivity of cancer cells to EZH2 inhibitor

10. The phytochemical vitexin and syringic acid derived from foxtail fillet bran inhibit breast cancer cells proliferation via GRP78/SREBP-1/SCD1 signaling axis

11. SCD1 promotes the stemness of gastric cancer stem cells by inhibiting ferroptosis through the SQLE/cholesterol/mTOR signalling pathway.

12. Lipid ratios representing SCD1, FADS1, and FADS2 activities as candidate biomarkers of early growth and adiposity

13. Concurrent Mutations in STK11 and KEAP1 Promote Ferroptosis Protection and SCD1 Dependence in Lung Cancer

14. miR-378 Activates the Pyruvate-PEP Futile Cycle and Enhances Lipolysis to Ameliorate Obesity in Mice

15. SCD1 sustains brown fat sympathetic innervation and thermogenesis during the long-term cold exposure.

16. β3 adrenergic receptor activation alleviated PM 2.5 -induced hepatic lipid deposition in mice.

17. The effect of milk polar lipids separated from butter serum on the lipid levels in the liver and the plasma of obese-model mouse (KK-Ay)

18. Dynamic role of Scd1 gene during mouse oocyte growth and maturation.

19. Stearoyl-CoA desaturase 1 deficiency exacerbates palmitate-induced lipotoxicity by the formation of small lipid droplets in pancreatic β-cells.

20. Stress-dependent inhibition of polarized cell growth through unbalancing the GEF/GAP regulation of Cdc42

21. Polymorphisms rs55710213 and rs56334587 regulate SCD1 expression by modulating HNF4A binding

22. Lipid ratios representing SCD1, FADS1, and FADS2 activities as candidate biomarkers of early growth and adiposity

23. Concurrent Mutations in STK11 and KEAP1 Promote Ferroptosis Protection and SCD1 Dependence in Lung Cancer

24. Blood Lipid Responses to Diets Enriched with Cottonseed Oil Compared With Olive Oil in Adults with High Cholesterol in a Randomized Trial.

25. Roles of miR-124-3p/Scd1 in urolithin A-induced brown adipocyte differentiation and succinate-dependent regulation of mitochondrial complex II.

26. miR-378 Activates the Pyruvate-PEP Futile Cycle and Enhances Lipolysis to Ameliorate Obesity in Mice

27. Polymorphisms rs55710213 and rs56334587 regulate SCD1 expression by modulating HNF4A binding.

28. Causative and Sanative dynamicity of ChREBP in Hepato-Metabolic disorders.

29. Structure and Mechanism of a Unique Diiron Center in Mammalian Stearoyl-CoA Desaturase.

30. Systems biology of ferroptosis: A modeling approach.

31. Oleic acid increases the transcriptional activity of FoxO1 by promoting its nuclear translocation and β-catenin binding in pancreatic β-cells.

32. Interleukin-6 derived from cutaneous deficiency of stearoyl-CoA desaturase- 1 may mediate metabolic organ crosstalk among skin, adipose tissue and liver.

33. Ablation of prolactin receptor increases hepatic triglyceride accumulation.

34. Dietary β-conglycinin prevents acute ethanol-induced fatty liver in mice.

35. Stearoyl-CoA desaturase regulates sorafenib resistance via modulation of ER stress-induced differentiation.

36. The influence of maternal dietary fat on the fatty acid composition and lipid metabolism in the subcutaneous fat of progeny pigs.

37. Stearoyl-CoA desaturase regulates inflammatory gene expression by changing DNA methylation level in 3T3 adipocytes.

38. Scd1 mammary-specific vector constructed and overexpressed in goat fibroblast cells resulting in an increase of palmitoleic acid and oleic acid.

39. Resistin and visfatin in steatotic and non-steatotic livers in the setting of partial hepatectomy under ischemia-reperfusion.

40. Deletion of circadian gene Per1 alleviates acute ethanol-induced hepatotoxicity in mice.

41. Oleate rescues INS-1E β-cells from palmitate-induced apoptosis by preventing activation of the unfolded protein response.

42. Flightless I homolog negatively regulates ChREBP activity in cancer cells.

43. The adverse outcome pathway concept: a pragmatic tool in toxicology.