Search

Your search keyword '"Steven C. Campbell"' showing total 7 results
Start Over Author "Steven C. Campbell" Publisher elsevier
7 results on '"Steven C. Campbell"'

1. Selective Use of Neoadjuvant Targeted Therapy Is Associated with Greater Achievement of Partial Nephrectomy for High-complexity Renal Masses in a Solitary Kidney

Author

Worapat Attawettayanon, Yosuke Yasuda, JJ H. Zhang, Akira Kazama, Nityam Rathi, Carlos Munoz-Lopez, Kieran Lewis, Snehi Shah, Jianbo Li, João Pedro Emrich Accioly, Rebecca A. Campbell, Shetal Shah, Andrew Wood, Jihad Kaouk, Georges-Pascal Haber, Mohamad Eltemamy, Venkatesh Krishnamurthi, Robert Abouassaly, Christopher Weight, Ithaar Derweesh, and Steven C. Campbell

Subjects
Partial nephrectomy, High tumor complexity, Neoadjuvant therapy, Tyrosine kinase inhibitors, Renal cell carcinoma, Solitary kidney, Diseases of the genitourinary system. Urology, RC870-923, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

Background: Partial nephrectomy (PN) is preferred for a renal mass in a solitary kidney (RMSK), although tumors with high complexity can be challenging. Objective: To evaluate the evolution of RMSK management with a focus on achievement of PN. Design, setting, and participants: Patients with nonmetastatic RMSK (n = 499) were retrospectively reviewed; 133 had high tumor complexity, including 80 in the pre-tyrosine kinase inhibitor (TKI) era (1999–2008) and 53 in the TKI era (2009–2022). After 2009, 23/53 patients received neoadjuvant TKI and 30/53 had immediate-surgery. Outcome measurements and statistical analysis: Functional outcomes, adverse events and complications, dialysis-free survival, and recurrence-free survival (RFS) were the measures evaluated. Mann-Whitney and χ2 tests were used to compare cohorts, and the log-rank test was applied for survival analyses. Results and limitations: Overall, the median RENAL score was 10 and the median tumor diameter was 5.2 cm. Demographic characteristics, tumor diameter, and RENAL scores were similar between the pre-TKI-era and TKI-era groups. In the TKI era, 23/53 patients (43%) with clear-cell histology were selected for neoadjuvant TKI. These 23 patients had a greater median tumor diameter (7.1 vs 4.4 cm; p = 0.02) and RENAL score (11 vs 10; p = 0.07). After TKI treatment, the median tumor diameter decreased to 5.6 cm and the RENAL score to 9, and tumor volume was reduced by 59% (all p

Published
2023
Full Text
View/download PDF

2. Defining Tumour Shape Irregularity for Preoperative Risk Stratification of Clinically Localised Renal Cell Carcinoma

Author

Hajime Tanaka, Shohei Fukuda, Koichiro Kimura, Yuki Fukawa, Kouhei Yamamoto, Hiroshi Fukushima, Shingo Moriyama, Yosuke Yasuda, Sho Uehara, Yuma Waseda, Soichiro Yoshida, Minato Yokoyama, Yoh Matsuoka, Kazutaka Saito, Ukihide Tateishi, Steven C. Campbell, and Yasuhisa Fujii

Subjects
Adverse pathology, Nephrectomy, Recurrence-free survival, Renal cell carcinoma, Tumour shape irregularity, Diseases of the genitourinary system. Urology, RC870-923, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

Background: Unexpected adverse pathology is a major concern in surgical management of clinically localised renal cell carcinoma (RCC). Further studies are needed to improve preoperative risk stratification. Objective: To define and classify tumour shape irregularity (TSI) based on preoperative imaging, and to investigate its effect on pathological and oncological outcomes in clinically localised RCC. Design, setting, and participants: We retrospectively analysed 474 patients with cT1-2N0M0 RCC managed by partial or radical nephrectomy. Preoperative dynamic computed tomography was used to define and classify TSI, graded as 1 (completely elliptical shape), 2 (elliptical shape with minor and focal protrusions), or 3 (nonelliptical shape presenting with major and/or extensive protrusions). Intervention: Partial or radical nephrectomy. Outcome measurements and statistical analysis: A logistic regression analysis evaluated the risk factors for pT3a upstaging and Fuhrman grade 3–4. A Cox proportional hazard analysis assessed preoperative variables for recurrence-free survival (RFS). Results and limitations: The median tumour size was 3.5 cm, and 94 patients (20%) had (R)adius (tumour size as maximal diameter), (E)xophytic/endophytic properties of tumour, (N)earness of tumour deepest portion to collecting system or sinus, (A)nterior (a)/posterior (p) descriptor, and (L)ocation relative to polar lines (RENAL) score ≥10. TSI was graded as 1, 2, and 3 in 214 (45%), 151 (32%), and 109 (23%) patients, respectively. Higher TSI was significantly associated with a larger tumour size and a higher RENAL score. Overall, pT3a upstaging and Fuhrman grade 3–4 were observed in 45 (9.5%) and 116 patients (31% in 380 clear cell RCC cases), respectively. The incidence of pT3a upstaging and Fuhrman grade 3–4 was significantly higher in patients with higher TSI (0.5%, 8.6%, and 28% for pT3a upstaging and 12%, 33%, and 60% for Fuhrman grade 3–4 in TSI 1, 2, and 3 groups, respectively). In multivariable analyses, higher TSI was independently associated with adverse pathological outcomes. During the median follow-up of 6.0 yr, 49 patients (10%) developed recurrence. Multivariable analyses demonstrated that older age and higher TSI were independent risk factors for worse RFS. The limitations include the retrospective design. Conclusions: TSI may be a useful adjunct in preoperative risk stratification for adverse pathology and recurrence after surgery in clinically localised RCC. Patient summary: Tumour shape irregularity is significantly associated with unfavourable pathological outcomes, that is, locally advanced stage or high-grade cancer, and with a higher recurrence rate after surgery in patients with clinically localised renal cell carcinoma. Preoperative evaluation of the tumour shape may help in patient counselling and treatment decisions.

Published
2023
Full Text
View/download PDF

3. Split Renal Function Is Fundamentally Important for Predicting Functional Recovery After Radical Nephrectomy

Author

Nityam Rathi, Yosuke Yasuda, Diego Aguilar Palacios, Worapat Attawettayanon, Jianbo Li, Bimal Bhindi, R. Houston Thompson, Michael A. Liss, Ithaar H. Derweesh, Christopher J. Weight, Mohammed Eltemamy, Robert Abouassaly, and Steven C. Campbell

Subjects
Radical nephrectomy, Split renal function, Parenchymal volume analysis, Kidney cancer, Functional compensation, Diseases of the genitourinary system. Urology, RC870-923, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

While partial nephrectomy (PN) is generally preferred for localized renal cell carcinoma (RCC), radical nephrectomy (RN) is occasionally required. A new-baseline glomerular filtration rate (NBGFR) >45 ml/min/1.73 m2 after kidney cancer surgery is associated with strong survival outcomes. If NBGFR after RN will be above this threshold and the tumor has increased oncologic potential, RN may be a relevant consideration. Predicting NBGFR, defined as the GFR at 3–12 mo after RN, has been challenging owing to omission of two important parameters: split renal function (SRF) and renal function compensation (RFC). Our objective was to evaluate a simple SRF-based model in comparison to five published non–SRF-based models using data from a retrospective cohort of 445 RN patients. SRF was obtained via readily available semiautomated software (FUJIFILM Medical Systems) that provides differential parenchymal volume analysis on the basis of preoperative imaging. Our conceptually simple and clinically implementable SRF-based model more accurately predicts NBGFR after RN than five published non–SRF-based models (all p 45 ml/min/1.73 m2 (all p

Published
2022
Full Text
View/download PDF

5. Contributors

Author

Robert Abouassaly, Paul Abrams, Mark C. Adams, Ashok Agarwal, Mohamad E. Allaf, James Kyle Anderson, Karl-Erik Andersson, Kenneth W. Angermeier, Emmanuel S. Antonarakis, Dean G. Assimos, Anthony Atala, Darius J. Bägli, John Maynard Barry, Julia Spencer Barthold, Stuart B. Bauer, Clair J. Beard, Arie S. Belldegrun, Mitchell C. Benson, Brian M. Benway, Ryan Kent Berglund, David M. Berman, Sam B. Bhayani, Jay Todd Bishoff, Michael L. Blute, Joseph G. Borer, George J. Bosl, Charles B. Brendler, Gregory A. Broderick, James D. Brooks, Arthur L. Burnett, Jeffrey A. Cadeddu, Anthony A. Caldamone, Steven C. Campbell, Douglas A. Canning, Michael A. Carducci, Michael C. Carr, Peter R. Carroll, Herbert Ballentine Carter, Anthony J. Casale, Pasquale Casale, William J. Catalona, R. Duane Cespedes, Michael B. Chancellor, Christopher R. Chapple, Christopher J. Chermansky, Robert L. Chevalier, George K. Chow, Jeanne S. Chow, Benjamin I. Chung, Ralph V. Clayman, Michael Joseph Conlin, Raymond A. Costabile, Paul L. Crispen, Juanita M. Crook, Douglas M. Dahl, Anthony V. D’Amico, John W. Davis, G. Joel DeCastro, John D. Denstedt, Theodore L. DeWeese, David Andrew Diamond, Roger R. Dmochowski, Leo R. Doumanian, Marcus Drake, Branden Duffey, Daniel D. Dugi, James A. Eastham, Louis Eichel, Mario A. Eisenberger, Jonathan I. Epstein, Carlos R. Estrada, Robert L. Fairchild, Amr Fergany, Michael N. Ferrandino, Lynne R. Ferrari, James H. Finke, John M. Fitzpatrick, Robert C. Flanigan, Stuart M. Flechner, Tara Lee Frenkl, Dominic C. Frimberger, Pat F. Fulgham, John P. Gearhart, Glenn S. Gerber, Jason L. Gerboc, Robert H. Getzenberg, Islam A. Ghoneim, Inderbir S. Gill, Timothy D. Gilligan, David A. Goldfarb, Marc Goldstein, Leonard G. Gomella, Mark L. Gonzalgo, Ethan J. Halpern, Misop Han, Philip M. Hanno, Harry W. Herr, Sender Herschorn, Thomas H.S. Hsu, Mark Hurwitz, Douglas A. Husmann, Thomas W. Jarrett, J. Stephen Jones, Gerald H. Jordan, David B. Joseph, Martin Kaefer, Jihad H. Kaouk, Irving D. Kaplan, Louis R. Kavoussi, Parviz K. Kavoussi, Patrick A. Kenney, Antoine E. Khoury, Roger Sinclair Kirby, Eric A. Klein, Kathleen C. Kobashi, Michael O. Koch, John N. Krieger, Bradley P. Kropp, Alexander Kutikov, Sarah M. Lambert, Raymond S. Lance, Brian R. Lane, William A. Larchian, Richard S. Lee, Herbert Lepor, Seth P. Lerner, John A. Libertino, W. Marston Linehan, James E. Lingeman, Richard Edward Link, Mark S. Litwin, Stacy Loeb, Yair Lotan, Tom F. Lue, Dawn Lee MacLellan, Stanley Bruce Malkowicz, Vitaly Margulis, Ranjiv I. Mathews, Surena F. Matin, Brian R. Matlaga, Steven D. Mawhorter, Kurt A. McCammon, W. Scott McDougal, Elspeth M. McDougall, James M. McKiernan, Alan W. McMahon, Thomas Anthony McNicholas, Alan Keith Meeker, Cathy Mendelsohn, Carlos E. Méndez-Probst, Maxwell V. Meng, David C. Miller, Ian Milsom, Manoj Monga, Drogo K. Montague, Courtenay Kathryn Moore, Alvaro Morales, Allen F. Morey, Michael J. Morris, John P. Mulhall, Stephen Y. Nakada, Joel B. Nelson, J. Curtis Nickel, Victor W. Nitti, Andrew C. Novick, Michael C. Ost, Priya Padmanabhan, Jeffrey S. Palmer, Lane S. Palmer, John M. Park, Alan W. Partin, Christopher K. Payne, Margaret S. Pearle, Craig A. Peters, Andrew C. Peterson, Curtis A. Pettaway, Paul K. Pietrow, Louis Leon Pisters, Elizabeth A. Platz, Emilio D. Poggio, John C. Pope, Jeannette M. Potts, Glenn M. Preminger, John C. Rabets, Raymond Robert Rackley, Hassan Razvi, Neil M. Resnick, Lee Richstone, Richard C. Rink, Michael L. Ritchey, Ronald Rodriguez, Claus G. Roehrborn, Eric S. Rovner, Edmund Sabanegh, Arthur I. Sagalowsky, Richard A. Santucci, Peter T. Scardino, Harriette Miles Scarpero, Anthony J. Schaeffer, Edward M. Schaeffer, Howard I. Scher, Douglas S. Scherr, Richard N. Schlussel, Francis X. Schneck, Michael J. Schwartz, Robert C. Shamberger, Ellen Shapiro, David S. Sharp, Joel Sheinfeld, Linda Marie Dairiki Shortliffe, Daniel A. Shoskes, Jennifer D.Y. Sihoe, Iqbal Singh, Donald G. Skinner, Eila C. Skinner, Joseph A. Smith, Warren T. Snodgrass, Graham Sommer, Ramaprasad Srinivasan, Joph Steckel, John P. Stein, Andrew J. Stephenson, Cora N. Sternberg, Jack W. Strandhoy, Li-Ming Su, Stasa D. Tadic, Ian M. Thompson, Joanna Maya Togami, Edouard J. Trabulsi, Howard Trachtman, Paul J. Turek, Robert G. Uzzo, Sandip P. Vasavada, Robert W. Veltri, Manish A. Vira, Patrick C. Walsh, Thomas J. Walsh, Alan J. Wein, Robert M. Weiss, Hunter Wessells, Wesley M. White, Jack Christian Winters, J. Stuart Wolf, Christopher G. Wood, David P. Wood, John R. Woodard, Chad Wotkowicz, Subbarao V. Yalla, C.K. Yeung, Naoki Yoshimura, and Richard N. Yu

Published
2012
Full Text
View/download PDF

6. Malignant Renal Tumors

Author

Steven C. Campbell and Brian R. Lane

Subjects
Pathology, medicine.medical_specialty, Malignant renal tumors, business.industry, Medicine, business
Published
2012
Full Text
View/download PDF

7. Contributors

Author

Clément-Claude Abbou, Neil A. Abrahams, Bulent Akduman, Thomas Anderson, Gerald L. Andriole, Ronald E. Anglade, Seetharaman Ashok, R. Joseph Babaian, Richard K. Babayan, David G. Bostwick, Simon R.J. Bott, Steven C. Campbell, Eduardo Canto, David Crawford, Paul Crispen, Philipp Dahm, John W. Davis, Frans M.J. Debruyne, Steven J. DiBiase, Bob Djavan, Ehab El-Gabry, Lars Ellison, Paul F. Engstrom, Abelardo Errejon, John M. Fitzpatrick, Neil Fleshner, Eduard J. Gamito, Ellen Gaynor, Glen Gejerman, Inderbir S. Gill, Phillip C. Ginsberg, Ciril J. Godec, Kazuo Gohji, Leonard G. Gomella, Richard Greenberg, Richard C. Harkaway, Beth A. Hellerstedt, Eric M. Horwitz, András Hoznek, William B. Isaacs, Jonathan Izawa, Stephen C. Jacobs, Matthew Karlovsky, Michael Kattan, Aaron E. Katz, Roger S. Kirby, Sohei Kitazawa, Laurence Klotz, Vladimir Kolenko, Andre Konski, Richard E. Link, Stephan Madersbacher, S. Bruce Malkowicz, Michael Marberger, Fray Marshall, T. Casey McCullough, Kevin McEleny, Liza McLornan, Anoop M. Meraney, Ronald A. Morton, Judd Moul, Mark A. Moyad, Jack H. Mydlo, Charles Myers, Vivek Narain, Don W.W. Newling, Brian Nicholson, Carl Olsson, David P. Paulson, Kenneth J. Pienta, Alan Pollack, Isaac Powell, Timothy L. Ratliff, Mesut Remzi, Martin Resnick, Vincent Ricchiuti, Eric S. Rovner, Daniel B. Rukstalis, Ihor C. Sawczuk, Peter Scardino, Paul F. Schellhammer, Claude C. Schulman, Ahmad Shabsigh, Neil Sherman, D. Robert Siemens, Kevin Slawin, Barry Stein, Mitchell S. Steiner, Chandru P. Sundaram, Dan Theodorescu, Edouard J. Trabulsi, Aubrey Turner, Robert G. Uzzo, Richard K. Valicenti, Michael R. Van Balken, Deborah Watkins-Bruner, R. William G. Watson, Alan J. Wein, Magali Williamson, David Wood, Jianfeng Xu, Paul Yonover, and A.R. Zlotta

Published
2003
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results