11 results on '"T, Rousseau"'
Search Results
2. Should prenatal chromosomal microarray analysis be offered for isolated fetal growth restriction? A French multicenter study.
- Author
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Monier I, Receveur A, Houfflin-Debarge V, Goua V, Castaigne V, Jouannic JM, Mousty E, Saliou AH, Bouchghoul H, Rousseau T, Valat AS, Groussolles M, Fuchs F, Benoist G, Degre S, Massardier J, Tsatsaris V, Kleinfinger P, Zeitlin J, and Benachi A
- Subjects
- Adult, Female, France, Humans, Pregnancy, Retrospective Studies, Fetal Growth Retardation genetics, Microarray Analysis, Prenatal Diagnosis
- Abstract
Background: Compared with standard karyotype, chromosomal microarray analysis improves the detection of genetic anomalies and is thus recommended in many prenatal indications. However, evidence is still lacking on the clinical utility of chromosomal microarray analysis in cases of isolated fetal growth restriction., Objective: This study aimed to estimate the proportion of copy number variants detected by chromosomal microarray analysis and the incremental yield of chromosomal microarray analysis compared with karyotype in the detection of genetic abnormalities in fetuses with isolated fetal growth restriction., Study Design: This retrospective study included all singleton fetuses diagnosed with fetal growth restriction and no structural ultrasound anomalies and referred to 13 French fetal medicine centers over 1 year in 2016. Fetal growth restriction was defined as an estimated fetal weight of
- Published
- 2021
- Full Text
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3. Placental volume and other first-trimester outcomes: are there differences between fresh embryo transfer, frozen-thawed embryo transfer and natural conception?
- Author
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Choux C, Ginod P, Barberet J, Rousseau T, Bruno C, Sagot P, Astruc K, and Fauque P
- Subjects
- Adult, Birth Weight, Body Mass Index, Case-Control Studies, Chorionic Gonadotropin, beta Subunit, Human metabolism, Female, France, Humans, Infant, Newborn, Male, Peptide Fragments metabolism, Postpartum Hemorrhage pathology, Postpartum Hemorrhage prevention & control, Pregnancy, Pregnancy Trimester, First, Pregnancy-Associated Plasma Protein-A metabolism, Retrospective Studies, Smoking, Uterine Artery pathology, Embryo Transfer methods, Fertilization, Placenta physiology
- Abstract
Research Question: Does mode of conception influence placental volume and other first-trimester outcomes?, Design: This retrospective single-centre case-control study led in Dijon University Hospital included 252 singleton pregnancies (84 IVF with either fresh embryo transfer or frozen-thawed embryo transfer [FET] and 168 natural conceptions). First-trimester placental volume, uterine artery pulsatility index and maternal serum PAPP-A and beta-HCG were measured. Statistical analyses were adjusted for gestational age, the newborn's gender, maternal age, parity, body mass index and smoking status., Results: Placental volume was significantly greater in the FET group than in the control group (P = 0.043) and fresh embryo transfer (P = 0.023) groups. At birth, fresh embryo transfer newborns were significantly smaller than controls (P = 0.01) and FET newborns (P = 0.008). Postpartum haemorrhage was far more frequent in FET than in controls and fresh embryo transfer group (38.1%, 2.6% and 1.9%, respectively; P < 0.0001). Placental volume positively correlated with PAPP-A, beta-HCG and the newborn's birth weight, and negatively correlated with uterine artery pulsatility index., Conclusions: Placental volume and other first-trimester parameters are modified by IVF with fresh embryo transfer and FET compared with natural conception, but with opposite trends. Given the different protocols used for these techniques, hormonal treatment per se may have a major effect on pregnancy outcomes through the modification of placental invasiveness., (Copyright © 2019 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.)
- Published
- 2019
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4. Extremely premature infants: How does death in the delivery room influence mortality rates in two level 3 centers in France?
- Author
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Forner O, Schiby A, Ridley A, Thiriez G, Mugabo I, Morel V, Mulin B, Filiatre JC, Riethmuller D, Levy G, Semama D, Martin D, Chantegret C, Bert S, Godoy F, Sagot P, Rousseau T, and Burguet A
- Subjects
- Female, France, Humans, Infant, Infant, Extremely Premature, Infant, Newborn, Pregnancy, Registries, Retrospective Studies, Tertiary Care Centers statistics & numerical data, Delivery Rooms statistics & numerical data, Infant Mortality, Intensive Care Units, Neonatal statistics & numerical data
- Abstract
Objectives: Mortality rates of very preterm infants may vary considerably between healthcare facilities depending on the neonates' place of inclusion in the cohort study. The objective of this study was to compare the mortality rates of live-born extremely preterm neonates observed in two French tertiary referral hospitals, taking into account the occurrence of neonatal death both in the delivery room and in the neonatal intensive care unit (NICU)., Methods: Retrospective observational study including all pregnancy terminations, stillbirths and live-born infants within a 22- to 26-week
0/6 gestational age range was registered by two French level 3 university centers between 2009 and 2013. The mortality rates were compared between the two centers according to two places of inclusion: either the delivery room or the NICU., Results: A total of 344 infants were born at center A and 160 infants were born at center B. Among the live-born neonates, the rates of neonatal death were similar in center A (54/125, 43.2%) and center B (33/69, 47.8%; P=0.54). However, neonatal death occurred significantly more often in the delivery room at center A (31/54, 57.4%) than at center B (6/33, 18.2%; P<0.001). Finally, the neonatal death rate of live-born very preterm neonates admitted to the NICU was significantly lower in center A (25/94, 26.6%) than in center B (27/63, 42.9%; P=0.03)., Conclusions: This study points out how the inclusion of deaths in the delivery room when comparing neonatal death rates can lead to a substantial bias in benchmarking studies. Center A and center B each endorsed one of the two models of preferential place of neonatal death (delivery room or NICU) detailed in European studies. The reasons behind the two different models and their impact on how parents perceive supporting their neonate need further investigation., (Copyright © 2018 Elsevier Masson SAS. All rights reserved.)- Published
- 2018
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5. Validity of rotational laxity coupled with anterior translation of the knee: A cadaveric study comparing radiostereometry and the Rotab®.
- Author
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Senioris A, Rousseau T, L'Hermette M, Gouzy S, Duparc F, and Dujardin F
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- Aged, Aged, 80 and over, Anterior Cruciate Ligament Injuries complications, Biomechanical Phenomena, Cadaver, Humans, Joint Instability etiology, Joint Instability physiopathology, Middle Aged, Reproducibility of Results, Rotation, Anterior Cruciate Ligament Injuries physiopathology, Arthrometry, Articular, Joint Instability diagnosis, Knee Joint physiopathology, Radiostereometric Analysis
- Abstract
Background: In current practice, anterior cruciate ligament (ACL) tears can be diagnosed using several devices to measure anterior tibial translation and rotational knee laxity, but these measures are never collected together. The Rotab®, which yields simultaneous measurements of anterior tibial translation and passive lower limb rotation under stress, would therefore be advantageous in current practice, but its reliability has never been tested., Aim of Study: To evaluate the accuracy and reliability of the Rotab® compared to the reference system, radiostereometric analysis (RSA)., Methods: This anatomical study was conducted on 14 lower limbs collected from fresh cadavers. Simultaneous measurements of anterior tibial translation and rotation were obtained with both systems, with antero-posterior (AP) forces of 134N and 250N using the Rotab®. Measurements were made on intact ACL and then repeated after ACL section. Variables were analyzed in univariate analysis by ANOVA, and the intraclass correlation coefficient (ICC) between the systems was determined by the Bland and Altman method., Results: The difference between the two methods for evaluating anterior tibial translation was 0.05±0.98mm at 134N and 0.29±1.04mm at 250N. The correlation between the tests was high (r
134 =r250 =0.97, p=0.8). The difference between the two methods for rotational laxity was 0.69±2.7° at 134N and 0.5±0.6° at 250N. The Rotab® showed a significant difference only at 250N for rotational laxity after the ACL tear., Conclusion: The Rotab® is a reliable device to measure rotational laxity coupled with anterior translation of the knee., (Copyright © 2017 Elsevier B.V. All rights reserved.)- Published
- 2017
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6. [Correlation between the perineal-to-skull measurement by tranperineal ultrasound, failure of vaginal operative delivery and maternal-fetal morbidity].
- Author
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Tabard F, Feyeux C, Peyronel C, Rousseau T, Cottenet J, Sagot P, and Macé G
- Subjects
- Adult, Apgar Score, Cesarean Section statistics & numerical data, Female, Gestational Age, Humans, Intensive Care, Neonatal, Morbidity, Perineum injuries, Postpartum Hemorrhage epidemiology, Pregnancy, Retrospective Studies, Risk Factors, Treatment Failure, Extraction, Obstetrical adverse effects, Perineum diagnostic imaging, Skull diagnostic imaging, Skull embryology, Ultrasonography, Prenatal methods
- Abstract
Objectives: To assess the influence of the perineal-to-skull measurement by tranperineal ultrasound (TPU) on the outcome of vaginal operative extraction together with maternal and fetal morbidity., Materials and Methods: Retrospective, monocentric and descriptive study was done on 272 patients, from 2009 January 1st to 2009 December 31st. It compares the failure rate of instrumental extraction, total caesarean section rate together with the maternal morbidity (type of perineal tears and post-partum hemorrhage rate) and fetal morbidity (5' Apgar score, arterial pH, transfer in neonatal intensive care unit) to the values obtained with TPU., Results: There is a correlation between the perineal-to-skull measurements higher or equal to 50mm at TPU and the instrumental failure rate (<50mm 0.8% vs. ≥50mm 11.9%; P<0.0001), caesarean (0.9% vs. 33.3%; P<0.0001), post-partum haemorrhage (3% vs. 11.9%; P=0.02), et paediatric intervention (16.7% vs. 31%; P=0.03)., Conclusion: Perineal-to-skull distance measured with TPU higher or equal to 50mm is at risk of instrumental failure and maternal morbidity. Associated with clinical examination and usual obstetrical risk factors, TPU could be useful to the decision between operative vaginal delivery and prophylactic caesarean section., (Copyright © 2013 Elsevier Masson SAS. All rights reserved.)
- Published
- 2013
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7. [Impact of maternal age distribution on the expected live birth prevalence of Down's syndrome in the metropolitan France between 1965 and 2008].
- Author
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Rousseau T, Ferdynus C, Thauvin-Robinet C, Gouyon JB, and Sagot P
- Subjects
- Adolescent, Adult, Female, France epidemiology, Humans, Infant, Newborn, Middle Aged, Pregnancy, Prenatal Diagnosis statistics & numerical data, Prevalence, Young Adult, Down Syndrome epidemiology, Live Birth epidemiology, Maternal Age
- Abstract
Objectives: To evaluate the impact of demographic factors such as maternal age on the expected prevalence of Down's syndrome at birth., Patients and Methods: We used data from the French National Institute of Statistics (INSEE) concerning live births and maternal age. Expected prevalence at birth is derived from a mathematical regression model commonly used in biochemical screening., Results: We present continuous expected prevalence at birth over a long period, from 1965 to 2008. Over the last three decades, mean maternal age has increased by 4 years, leading to a two-fold increased in the expected live-birth prevalence of Down's syndrome infants, from 12.1 per 10,000 in 1977 to 21.7 per 10,000 in 2008., Conclusion: It is important to continue to consider the impact modifications in demographic factors, such as maternal age, particularly in the evaluation of screening practices and policies for Down's syndrome., (Copyright 2010 Elsevier Masson SAS. All rights reserved.)
- Published
- 2010
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8. [Variations in the prevalence of Down's syndrome in the French population between 1978 and 2005].
- Author
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Rousseau T, Amar E, Ferdynus C, Thauvin-Robinet C, Gouyon JB, and Sagot P
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- Abortion, Induced statistics & numerical data, Adolescent, Adult, Female, France epidemiology, Humans, Infant, Newborn, Middle Aged, Pregnancy, Prevalence, Young Adult, Down Syndrome epidemiology, Live Birth epidemiology, Maternal Age, Prenatal Diagnosis statistics & numerical data
- Abstract
Objectives: To evaluate the impact of maternal age and prenatal diagnosis on the prevalence of Down's syndrome at birth in French population sample., Patients and Methods: Data concerning Down's syndrome from 1978 to 2005 were obtained from the REMERA registry of congenital malformations. The population surveyed was approximately 10% of French births. We studied total prevalence, live-birth prevalence and the prevalence of pregnancy termination after prenatal diagnosis., Results: Mean maternal age has risen from 26 to 30 years over the study period. Total prevalence of Down's syndrome has increased from 14 per 10,000 in 1978 to 23 per 10,000 live-births in 2005. Termination of pregnancy after prenatal diagnosis of Down's syndrome gradually increased reaching 78% in 2005. Live-birth prevalence decreased from 14 per 10,000 in 1978 to 5.1 per 10,000 in 2005., Conclusion: This work shows the importance of continuing the epidemiological survey of Down's syndrome in France, especially because of the modification in population ageing as well in prenatal screening policies for Down's syndrome., (Copyright 2010 Elsevier Masson SAS. All rights reserved.)
- Published
- 2010
- Full Text
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9. [Liveborn birth-weight of single and uncomplicated pregnancies between 28 and 42 weeks of gestation from Burgundy perinatal network].
- Author
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Rousseau T, Ferdynus C, Quantin C, Gouyon JB, and Sagot P
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- Female, France, Gestational Age, Humans, Infant, Newborn, Male, Medical Records, Pregnancy, Reference Standards, Reference Values, Retrospective Studies, Sex Distribution, Biometry methods, Birth Weight, Pregnancy Trimester, Second, Pregnancy Trimester, Third
- Abstract
Objectives: To build a reference chart for birth weight according to gestational age based on a newborn population from single uncomplicated pregnancies., Materials and Methods: We have used data from the Burgundy perinatal network for the years 2000 to 2005. We can exclude, with a validate linkage procedure of all mother-newborn couples, the whole of newborns from pregnancies complicated by mellitus diabetes or pre eclampsia. After statistical validation, the birth weights were modelled and graphically represented., Results: We have used 105,665 data from the "healthy" sample to construct a birth weight distribution according to gestational age at 28 to 42 weeks'. Results are also represented adjusted for sex., Conclusion: We present an original birth weight distribution according to gestational age from a recent French population sample. Exclusion of maternal conditions which may affect fetal growth modify the data distribution, mainly for low birth weights and premature deliveries. Used in clinical practice, it could lead to better identify newborns with increased risk of postnatal complications.
- Published
- 2008
- Full Text
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10. Spondylocostal dysostosis, anal and genitourinary malformations in a fetal case: a new case of Casamassima-Morton-Nance syndrome?
- Author
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Thauvin-Robinet C, Laurent N, Rousseau T, Couvreur S, Cusin V, Callier P, Mugneret F, Durand C, Huet F, Sagot P, and Faivre L
- Subjects
- Dysostoses genetics, Fetus abnormalities, Humans, Ribs abnormalities, Spine abnormalities, Syndrome, Abnormalities, Multiple genetics, Anal Canal abnormalities, Dysostoses pathology, Urogenital Abnormalities genetics
- Abstract
Casamassima-Morton-Nance syndrome belongs to the heterogeneous group of spondylocostal dysostoses (SCD) represented by a large heterogeneous group in which diverse diagnoses, associations and modes of inheritance are found. Common features include segmentation abnormalities of the vertebrae and ribs. Here, we report on a fetal case with spondylocostal dysostosis, anal and genitourinary malformations and discuss Casamassima-Morton-Nance syndrome.
- Published
- 2007
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11. [Voluntary interruption of pregnancy: comparative study between 1982 and 1996 in the main center of Côte d'Or. Study of women having repeat voluntary interruption of pregnancy].
- Author
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Douvier S, Lordier-Huynh-Ba C, Rousseau T, and Reynaud I
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- Abortion, Induced psychology, Adolescent, Adult, Female, Ghana, Humans, Marital Status, Middle Aged, Parity, Pregnancy, Retrospective Studies, Socioeconomic Factors, Abortion, Induced statistics & numerical data
- Abstract
Unlabelled: Since the egal use of induced abortion (1975), all the studies have shown a relative stability of the abortion rate related to delivery. Otherwise since 1985 we have noted an increase of repeat abortions., Objective: We compared in same center two populations of aborters with a fifteen year's interval. Then we analysed the psyco-social conditions of patients who had more than one abortion (R)., Methods: It was a comparative study between 1982 and 1996 in the main center of Côte d'Or (France). A representative sample of patients coming for abortion was retrospectively compared, (348 for 1982 and 343 for 1996)., Results: There were more not married patients (p = 0.0003), more nulliparous women (p = 0.0017) and more nulligestities' one (p = 0.03) in 1996 than 1982. The interval between the previous pregnancy and in 1996 (p = 0.03). Repeat abortions (R) represented 15.8% in 1982 and 21.6% in 1996. Women who have had two or more abortions had increased significantly between 1982 (1.4%) and 1996 (5.2%) (p = 0.013). The R patients had more living children than patients who accessed for the first time at abortion (noR) in the two periods (p = 0.0003) and there were more women less thirty years old in the R group in 1996 than in 1992 (p < 0.05). The R mean age for the first abortion and for the first pregnancy were lower than the noR group in 1996: respectively 23.7 years versus 27.4% years (p = 0.00009) and 20.8 years versus 23.7 years (p = 0.0001). There were no significant difference between R and noR groups with regards of contraceptive failing, the reasons of abortion and the socio-professional categories., Conclusions: There were no difference in the number of abortion between 1982 and 1996. However we noted an increase of repeat abortion. This group was characterised by great socio-economic problems, unstable couples and ambivalence with wish of pregnancy and no wish of children. It seemed exist a real psycho-social precariousness. Actually, this population was perfectly aware of contraceptive methods.
- Published
- 2001
- Full Text
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