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Your search keyword '"Topçu, G."' showing total 3 results
Start Over Author "Topçu, G." Publisher elsevier
3 results on '"Topçu, G."'

1. Antioxidant activity of Erica arborea.

Author

Ay M, Bahadori F, Oztürk M, Kolak U, and Topçu G

Subjects
Antioxidants administration & dosage, Antioxidants therapeutic use, Biphenyl Compounds, Ferrozine chemistry, Flowers, Humans, Inhibitory Concentration 50, Linoleic Acid chemistry, Picrates chemistry, Plant Extracts administration & dosage, Plant Extracts therapeutic use, Plant Leaves, Superoxides chemistry, Antioxidants pharmacology, Ericaceae, Phytotherapy, Plant Extracts pharmacology
Abstract

The antioxidant properties of the methanol extract of leaves and flowers of Erica arborea and the ethyl acetate, butanol and water soluble fractions were investigated. The ethyl acetate extract was found to be the richest for phenolic and flavonoid content which showed the highest antioxidant activity.

Published
2007
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2. Diterpenes from Sideritis argyrea.

Author

Topçu G, Gören AC, Kiliç T, Yildiz YK, and Tümen G

Subjects
Diterpenes isolation & purification, Humans, Magnetic Resonance Spectroscopy, Mass Spectrometry, Plant Extracts chemistry, Plant Extracts isolation & purification, Spectrophotometry, Infrared, Diterpenes chemistry, Lamiaceae, Plants, Medicinal chemistry
Abstract

The known ent-kaurene diterpenes 1-9 and a new ent-labdane, ent-6beta,8alpha-dihydroxylabda-13(16),14-diene (10), were isolated from the whole plant of Sideritis argyrea. Their structures were elucidated based on one- and two-dimensional NMR techniques and HRMS.

Published
2001
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3. Diterpenes from the berries of Juniperus excelsa.

Author

Topçu G, Erenler R, Cakmak O, Johansson CB, Celik C, Chai HB, and Pezzuto JM

Subjects
Animals, Anti-Bacterial Agents isolation & purification, Anti-Bacterial Agents pharmacology, Antineoplastic Agents chemistry, Antineoplastic Agents isolation & purification, Antineoplastic Agents pharmacology, Diterpenes isolation & purification, Diterpenes pharmacology, Hexanes chemistry, Humans, KB Cells drug effects, Leukemia P388 drug therapy, Microbial Sensitivity Tests, Mycobacterium tuberculosis drug effects, Nuclear Magnetic Resonance, Biomolecular, Plant Extracts isolation & purification, Plant Extracts pharmacology, Spectrophotometry, Infrared, Spectrophotometry, Ultraviolet, Tumor Cells, Cultured drug effects, Anti-Bacterial Agents chemistry, Diterpenes chemistry, Fruit chemistry, Juniperus chemistry, Plant Extracts chemistry
Abstract

From the hexane extract of berries of Juniperus excelsa, one new and four known diterpenes were isolated besides a known sesquiterpene. The structures of the known diterpenes were identified as isopimaric, isocommunic, (-)ent-trans communic and sandracopimaric acids, along with the sesquiterpene 4a-hydroxycedrol and the new compound which was elucidated as 3 alpha-acetoxylabda-8(17),13(16),14-trien-19-oic acid (juniperexcelsic acid). Cytotoxic activity of the hexane extract was investigated against a panel of cell line and found highly active against LNCaP, KB-V (+VLB) and KB-V (-VLB) cell lines. Furthermore, the hexane and methanol extracts, and the new compound were found to be moderately active against Mycobacterium tuberculosis.

Published
1999
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