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1. IFP35 aggravates Staphylococcus aureus infection by promoting Nrf2-regulated ferroptosis

2. Triad3A-Mediated K48-Linked ubiquitination and degradation of TLR9 impairs mitochondrial bioenergetics and exacerbates diabetic cardiomyopathy

3. Idebenone alleviates doxorubicin-induced cardiotoxicity by stabilizing FSP1 to inhibit ferroptosis

4. Reveal the pharmacodynamic substances and mechanism of an edible medicinal plant Platycodonis radix inhibits tumor

5. UBR5 mediates colorectal cancer chemoresistance by attenuating ferroptosis via Lys 11 ubiquitin-dependent stabilization of Smad3-SLC7A11 signaling

6. A novel lncRNA GM47544 modulates triglyceride metabolism by inducing ubiquitination-dependent protein degradation of APOC3

7. Cellular and molecular biology of posttranslational modifications in cardiovascular disease

8. Synergistic induction of ferroptosis by targeting HERC1-NCOA4 axis to enhance the photodynamic sensitivity of osteosarcoma

9. Berbamine promotes ferroptosis of esophageal squamous cell carcinoma by facilitating USP51-mediated GPX4 ubiquitination and degradation

10. Exploring the oncogenic potential of Aiolos in lung cancer through OTUB1-mediated ubiquitination

11. TRIM59 is required for mouse GC-1 cell maintenance through modulating the ubiquitination of AXIN1

12. Construction and validation of a ubiquitination-related prognostic risk score signature in breast cancer

13. Anlotinib destabilizes PAX3-FOXO1 to induce rhabdomyosarcoma cell death via upregulating NEK2

14. Notoginsenoside R1 attenuates ischemic heart failure by modulating MDM2/β arrestin2-mediated β2-adrenergic receptor ubiquitination

15. TRIM6 promotes glioma malignant progression by enhancing FOXO3A ubiquitination and degradation

16. Blockade of the deubiquitinating enzyme USP48 degrades oncogenic HMGA2 and inhibits colorectal cancer invasion and metastasis

17. Engagement of N6-methyladenisine methylation of Gng4 mRNA in astrocyte dysfunction regulated by CircHECW2

18. Small molecule deoxynyboquinone triggers alkylation and ubiquitination of Keap1 at Cys489 on Kelch domain for Nrf2 activation and inflammatory therapy

19. Manganese inhibits SVCV infection by promoting the expression of STING and the subsequent activation of IFN

20. Branched-chain amino acids alleviate NAFLD via inhibiting de novo lipogenesis and activating fatty acid β-oxidation in laying hens

21. Decoding post-translational modifications for understanding stress tolerance in plant

22. Post-translational modifications: The potential ways for killing cancer stem cells

23. Ubiquitin-modifying enzymes in thyroid cancer:Mechanisms and functions

24. PRAME promotes proliferation of multiple myeloma cells through CTMP/Akt/p21/CCND3 axis by ubiquitinating CTMP and p21

25. E3 ubiquitin ligase TRIM31: A potential therapeutic target

26. A targetable PRR11-DHODH axis drives ferroptosis- and temozolomide-resistance in glioblastoma

27. FOXO1 regulates RUNX2 ubiquitination through SMURF2 in calcific aortic valve disease

28. Advances of E3 ligases in lung cancer

29. Mid1 promotes synovitis in rheumatoid arthritis via ubiquitin-dependent post-translational modification

30. O-GlcNAcylation regulates the stability of transferrin receptor (TFRC) to control the ferroptosis in hepatocellular carcinoma cells

31. Integrative omics reveals clues as to why Cynoglossus semilaevis pseudomales produce no W sperm

32. Citrus polymethoxyflavones degrade estrogen receptor-alpha (ERα) and combine with tamoxifen for the treatment of estrogen receptor-positive breast cancer

33. SIAH1 facilitates the migration and invasion of gastric cancer cells through promoting the ubiquitination and degradation of RECK

34. Nucleoporin 43 inhibits NF-κB pathway by targeting TRAF6 in miiuy croaker, Miichthys miiuy

35. Supplementary kumatakenin prevents esophagus cancer progression by blocking TRIM65-FASN axis-mediated metabolic reprogramming

36. NUF2 regulated the progression of hepatocellular carcinoma through modulating the PI3K/AKT pathway via stabilizing ERBB3

37. Inhibition the ubiquitination of ENaC and Na,K-ATPase with erythropoietin promotes alveolar fluid clearance in sepsis-induced acute respiratory distress syndrome

38. Hydralazine represses Fpn ubiquitination to rescue injured neurons via competitive binding to UBA52

39. Hepatocyte Deubiquitinating Enzyme OTUD5 Deficiency is a Key Aggravator for Metabolic Dysfunction-Associated Steatohepatitis by Disturbing Mitochondrial HomeostasisSummary

40. Intricate confrontation: Research progress and application potential of TRIM family proteins in tumor immune escape

41. Macrophage LMO7 deficiency facilitates inflammatory injury via metabolic-epigenetic reprogramming

42. The F-box-only protein 44 regulates pregnane X receptor protein level by ubiquitination and degradation

43. p53 accelerates endothelial cell senescence in diabetic retinopathy by enhancing FoxO3a ubiquitylation and degradation via UBE2L6

44. PreS1BP mediates inhibition of Hepatitis B virus replication by promoting HBx protein degradation

45. Screening for molecular glues – Challenges and opportunities

46. Dibutyl phthalate disrupts glycogen synthase kinase 3α essential for sperm motility

47. The lncRNA FENDRR inhibits colorectal cancer progression via interacting with and triggering GSTP1 ubiquitination by FBX8

48. LINC02253 promote the malignant phenotype of Colon adenocarcinoma cells by up-regulating WWP1-mediated SMAD3 ubiquitination

49. Significance of plant E3 ubiquitin ligases in NPK homeostasis: A review

50. Disruption of the Keap1-mTORC2 axis by cancer-derived Keap1/mLST8 mutations leads to oncogenic mTORC2-AKT activation

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