1. Diffuse-type tenosynovial giant cell tumor of the temporomandibular joint with skull base invasion: a report of 22 cases with literature review.
- Author
-
Liu Y, Fan BH, Tan YR, Zhu DW, Dong MJ, Wang LZ, Li J, Sun J, Zhang CP, Ji T, Yang WJ, Abdelrehem A, Wu YQ, and Zhong LP
- Subjects
- Adult, Female, Humans, Male, Retrospective Studies, Skull Base diagnostic imaging, Skull Base surgery, Temporomandibular Joint diagnostic imaging, Temporomandibular Joint surgery, Giant Cell Tumor of Tendon Sheath diagnostic imaging, Giant Cell Tumor of Tendon Sheath surgery, Neoplasm Recurrence, Local
- Abstract
Objectives: The aim of this study was to retrospectively analyze the clinical characteristics, surgical treatment, and prognosis of patients with diffuse-type tenosynovial giant cell tumor (D-TGCT) involving the temporomandibular joint (TMJ) and the skull base., Study Design: A retrospective study was performed in patients with D-TGCT involving the TMJ and the skull base at our institute from April 2009 to August 2018. Data on clinical characteristics, surgical treatment, and prognosis were collected and analyzed. A literature search on D-TGCT involving the TMJ was conducted and the data analyzed., Results: The study included 22 patients (14 males and 8 females), with an average age of 44 years. The main symptoms were headache and hearing limitation, accompanied by a swelling in the TMJ area. Magnetic resonance imaging (MRI) showed low signals on T1- and T2-weighted images. All lesions were completely removed. Temporal bone flap, titanium mesh, and temporal muscle flap were used for reconstruction. The recurrence rate was 4.5%. In the literature, 115 cases were reported. Surgery alone was performed in 88 cases; postoperative radiotherapy was performed in 19 cases; the tumor recurrence rates were 9.1% and 15.8% for the 2 procedures, respectively. All patients were alive at the end of the follow-up period., Conclusions: D-TGCT involving the TMJ and the skull base is a locally aggressive but benign lesion necessitating complete resection and has a good prognosis., (Copyright © 2020 Elsevier Inc. All rights reserved.)
- Published
- 2021
- Full Text
- View/download PDF