1. Exposure to air pollutants and mortality in hypertensive patients according to demography: a 10 year case-crossover study.
- Author
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Wong MC, Tam WW, Wang HH, Lao XQ, Zhang DD, Chan SW, Kwan MW, Fan CK, Cheung CS, Tong EL, Cheung NT, Tse LA, and Yu IT
- Subjects
- Adult, Aged, Air Pollution analysis, Cross-Over Studies, Demography, Female, Humans, Male, Middle Aged, Particulate Matter analysis, Seasons, Time Factors, Air Pollutants analysis, Air Pollution statistics & numerical data, Respiratory Tract Diseases mortality
- Abstract
This study evaluated whether short term exposures to NO2, O3, particulate matter <10 mm in diameter (PM10) were associated with higher risk of mortality. A total of 223,287 hypertensive patients attended public health-care services and newly prescribed at least 1 antihypertensive agent were followed-up for up to 5 years. A time-stratified, bi-directional case-crossover design was adopted. For all-cause mortality, significant positive associations were observed for NO2 and PM10 at lag 0-3 days per 10 μg/m(3) increase in concentration (excess risks 1.187%-2.501%). Significant positive associations were found for O3 at lag 1 and 2 days and the excess risks were 1.654% and 1.207%, respectively. We found similarly positive associations between these pollutants and respiratory disease mortality. These results were significant among those aged ≥65 years and in cold seasons only. Older hypertensive patients are susceptible to all-cause and respiratory disease-specific deaths from these air pollutants in cold weather., (Copyright © 2014 Elsevier Ltd. All rights reserved.)
- Published
- 2014
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