1. The global, regional, and national burden of gastro-oesophageal reflux disease in 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017
- Author
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Benn Sartorius, Ahmad Daryani, Arash Sarveazad, Ejaz Ahmad Khan, Feleke Mekonnen Demeke, Michael K. Hole, Akshaya Srikanth Bhagavathula, Cuong Tat Nguyen, Saeid Safiri, Mohammad Rabiee, Kevin S Ikuta, Olayinka Stephen Ilesanmi, Prasanna Mithra, Siavosh Nasseri-Moghaddam, Maciej Banach, Amrollah Sharifi, Ionut Negoi, Simon I. Hay, Abdollah Mohammadian-Hafshejani, Degena Bahrey Tadesse, Huyen Phuc Do, Ahmad Ghashghaee, Amir Khater, Taras Kavetskyy, Mukhammad David Naimzada, Saeed Amini, Farahnaz Joukar, Erkin M. Mirrakhimov, Varshil Mehta, Molly R Nixon, Yordanos Gizachew Yeshitila, Maseer Khan, David Laith Rawaf, Samer Hamidi, Berhe Etsay Tesfay, Hafiz Ansar Rasul Suleria, Parviz Vahedi, Marco Vacante, Dragos Virgil Davitoiu, Hossein Poustchi, Berhe Gebremichael, Javad Nazari, Danny V. Colombara, Hamideh Salimzadeh, Ali Bijani, Floriane Ausloos, Narjes Akhlaghi, Solomon Olum, Ashkan Afshin, Kaleab Alemayehu Zewdie, Yousef Veisani, Farshad Farzadfar, Zhi-Jiang Zhang, Theo Vos, Spencer L. James, Tuomo J. Meretoja, Ali Kabir, Ana-Laura Manda, Ghulam Mustafa, Adam Belay Wondmieneh, Hadush Gebremariam, Kia Vosoughi, Maryam Moossavi, Antonio Maria Borzì, Dhruv Mehta, Bach Xuan Tran, Bhaskar Thakur, Freweini Gebrearegay G. Tela, Baye Dagnew, Florian Fischer, Andrea Werdecker, Abadi Kahsu Gebre, Uday C Ghoshal, Derrick Tsoi, Andre Pascal Kengne, Milad Hasankhani, Antonio Biondi, Milad Mohammadoo-Khorasani, Sadaf G. Sepanlou, Shoaib Hassan, Muhammad U Khan, Mohammad Mahdi Zamani, Nicholas L S Roberts, Navid Rabiee, Rufus A. Adedoyin, Tomislav Mestrovic, Chi Linh Hoang, Rovshan Khalilov, Ai Koyanagi, Kathleen E. Corey, Umar Bacha, Gebre Teklemariam Demoz, Mohsen Naghavi, Abdulaziz M. Almulhim, Ali H. Mokdad, Reza Malekzadeh, M. Ashworth Dirac, Akram Pourshams, Seyed Sina Naghibi Irvani, Amin Soheili, Salman Rawaf, Fares Alahdab, Arash Etemadi, Saeed Safari, Hagazi Gebremedhin Kassaye, Gholamreza Roshandel, Alireza Rafiei, Huong Lan Thi Nguyen, Ghobad Moradi, and Ruth W Kimokoti more...
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Adult ,Male ,medicine.medical_specialty ,Latin Americans ,Adolescent ,Vomiting ,Population ,Disease ,Article ,Global Burden of Disease ,Young Adult ,03 medical and health sciences ,0302 clinical medicine ,Heartburn ,Gastro ,Epidemiology ,Prevalence ,Medicine ,Population growth ,Humans ,East Asia ,education ,Disease burden ,Aged ,Aged, 80 and over ,education.field_of_study ,Hepatology ,business.industry ,Gastroenterology ,Middle Aged ,030220 oncology & carcinogenesis ,Gastroesophageal Reflux ,Female ,030211 gastroenterology & hepatology ,Quality-Adjusted Life Years ,business ,Demography - Abstract
Summary Background Gastro-oesophageal reflux disease is a common chronic ailment that causes uncomfortable symptoms and increases the risk of oesophageal adenocarcinoma. We aimed to report the burden of gastro-oesophageal reflux disease in 195 countries and territories between 1990 and 2017, using data from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2017. Methods We did a systematic review to identify measurements of the prevalence of gastro-oesophageal reflux disease in geographically defined populations worldwide between 1990 and 2017. These estimates were analysed with DisMod-MR, a Bayesian mixed-effects meta-regression tool that incorporates predictive covariates and adjustments for differences in study design in a geographical cascade of models. Fitted values for broader geographical units inform prior distributions for finer geographical units. Prevalence was estimated for 195 countries and territories. Reports of the frequency and severity of symptoms among individuals with gastro-oesophageal reflux disease were used to estimate the prevalence of cases with no, mild to moderate, or severe to very severe symptoms at a given time; these estimates were multiplied by disability weights to estimate years lived with disability (YLD). Findings Data to estimate gastro-oesophageal reflux disease burden were scant, totalling 144 location-years (unique measurements from a year and location, regardless of whether a study reported them alongside measurements for other locations or years) of prevalence data. These came from six (86%) of seven GBD super-regions, 11 (52%) of 21 GBD regions, and 39 (20%) of 195 countries and territories. Mean estimates of age-standardised prevalence for all locations in 2017 ranged from 4408 cases per 100 000 population to 14 035 cases per 100 000 population. Age-standardised prevalence was highest (>11 000 cases per 100 000 population) in the USA, Italy, Greece, New Zealand, and several countries in Latin America and the Caribbean, north Africa and the Middle East, and eastern Europe; it was lowest ( more...
- Published
- 2020