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79 results on '"Sanchez, R. A."'

3. The ASTRI Mini-Array of Cherenkov telescopes at the Observatorio del Teide

Author

Scuderi, S., Giuliani, A., Pareschi, G., Tosti, G., Catalano, O., Amato, E., Antonelli, L.A., Becerra Gonzàles, J., Bellassai, G., Bigongiari, C., Biondo, B., Böttcher, M., Bonanno, G., Bonnoli, G., Bruno, P., Bulgarelli, A., Canestrari, R., Capalbi, M., Caraveo, P., Cardillo, M., Conforti, V., Contino, G., Corpora, M., Costa, A., Cusumano, G., D'Aì, A., de Gouveia Dal Pino, E., Della Ceca, R., Escribano Rodriguez, E., Falceta-Gonçalves, D., Fermino, C., Fiori, M., Fioretti, V., Fiorini, M., Gallozzi, S., Gargano, C., Garozzo, S., Germani, S., Ghedina, A., Gianotti, F., Giarrusso, S., Gimenes, R., Giordano, V., Grillo, A., Grivel Gelly, C., Impiombato, D., Incardona, F., Incorvaia, S., Iovenitti, S., La Barbera, A., La Palombara, N., La Parola, V., Lamastra, A., Lessio, L., Leto, G., Lo Gerfo, F., Lodi, M., Lombardi, S., Longo, F., Lucarelli, F., Maccarone, M.C., Marano, D., Martinetti, E., Mereghetti, S., Micciché, A., Millul, R., Mineo, T., Mollica, D., Morlino, G., Morselli, A., Naletto, G., Nicotra, G., Pagliaro, A., Parmiggiani, N., Piano, G., Pintore, F., Poretti, E., Olmi, B., Rodeghiero, G., Rodriguez Fernandez, G., Romano, P., Romeo, G., Russo, F., Sangiorgi, P., Saturni, F.G., Schwarz, J.H., Sciacca, E., Sironi, G., Sottile, G., Stamerra, A., Tagliaferri, G., Testa, V., Umana, G., Uslenghi, M., Vercellone, S., Zampieri, L., and Zanmar Sanchez, R.

Published
2022
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8. Electromagnetic moments of the odd-mass nickel isotopes 59−67Ni

Author

Müller, P., Kaufmann, S., Miyagi, T., Billowes, J., Bissell, M.L., Blaum, K., Cheal, B., Garcia Ruiz, R.F., Gins, W., Gorges, C., Heylen, H., Kanellakopoulos, A., Malbrunot-Ettenauer, S., Neugart, R., Neyens, G., Nörtershäuser, W., Ratajczyk, T., Rodríguez, L.V., Sánchez, R., Sailer, S., Schwenk, A., Wehner, L., Wraith, C., Xie, L., Xu, Z.Y., Yang, X.F., and Yordanov, D.T.

Published
2024
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37. Nuclear charge radii of 62−80Zn and their dependence on cross-shell proton excitations

Author

Xie, L., Yang, X.F., Wraith, C., Babcock, C., Bieroń, J., Billowes, J., Bissell, M.L., Blaum, K., Cheal, B., Filippin, L., Flanagan, K.T., Garcia Ruiz, R.F., Gins, W., Gaigalas, G., Godefroid, M., Gorges, C., Grob, L.K., Heylen, H., Jönsson, P., Kaufmann, S., Kowalska, M., Krämer, J., Malbrunot-Ettenauer, S., Neugart, R., Neyens, G., Nörtershäuser, W., Otsuka, T., Papuga, J., Sánchez, R., Tsunoda, Y., and Yordanov, D.T.

Published
2019
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38. New test of modulated electron capture decay of hydrogen-like 142Pm ions: Precision measurement of purely exponential decay

Author

Ozturk, F.C., Akkus, B., Atanasov, D., Beyer, H., Bosch, F., Boutin, D., Brandau, C., Bühler, P., Cakirli, R.B., Chen, R.J., Chen, W.D., Chen, X.C., Dillmann, I., Dimopoulou, C., Enders, W., Essel, H.G., Faestermann, T., Forstner, O., Gao, B.S., Geissel, H., Gernhäuser, R., Grisenti, R.E., Gumberidze, A., Hagmann, S., Heftrich, T., Heil, M., Herdrich, M.O., Hillenbrand, P.-M., Izumikawa, T., Kienle, P., Klaushofer, C., Kleffner, C., Kozhuharov, C., Knöbel, R.K., Kovalenko, O., Kreim, S., Kühl, T., Lederer-Woods, C., Lestinsky, M., Litvinov, S.A., Litvinov, Yu.A., Liu, Z., Ma, X.W., Maier, L., Mei, B., Miura, H., Mukha, I., Najafi, A., Nagae, D., Nishimura, T., Nociforo, C., Nolden, F., Ohtsubo, T., Oktem, Y., Omika, S., Ozawa, A., Petridis, N., Piotrowski, J., Reifarth, R., Rossbach, J., Sánchez, R., Sanjari, M.S., Scheidenberger, C., Sidhu, R.S., Simon, H., Spillmann, U., Steck, M., Stöhlker, Th., Sun, B.H., Susam, L.A., Suzaki, F., Suzuki, T., Torilov, S.Yu., Trageser, C., Trassinelli, M., Trotsenko, S., Tu, X.L., Walker, P.M., Wang, M., Weber, G., Weick, H., Winckler, N., Winters, D.F.A., Woods, P.J., Yamaguchi, T., Xu, X.D., Yan, X.L., Yang, J.C., Yuan, Y.J., Zhang, Y.H., and Zhou, X.H.

Published
2019
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44. Excessive downhill training leads to early onset of knee osteoarthritis.

Author

Morais, G.P., Chemerka, C., Masson, A., Seerattan, R.-A., da Rocha, A.L., Krawetz, R., da Silva, A.S.R., Herzog, W., Morais, Gustavo Paroschi, Chemerka, Colleen, Masson, Anand, Seerattan, Ruth-Anne, da Rocha, Alisson L, Krawetz, Roman, da Silva, Adelino Sanchez R, and Herzog, Walter

Abstract

Objective: Increased levels of pro-inflammatory cytokines are associated with the release of degradative enzymes leading to osteoarthritis (OA) development. Although physical exercise (PE) is generally recognized as beneficial for OA symptoms, excessive training workload and eccentric muscular exercise have increased OA risk. Here, we investigated the effects of excessive exercise workload and exercise type on systemic inflammation and knee joint OA.Methods: Mice were divided into five groups: sedentary (SED), uphill training (TRU), downhill training (TRD), excessive uphill training (ETU), and excessive downhill training (ETD) for an 8-week training intervention protocol.Results: ETD group had increased pro-inflammatory cytokines in serum, vastus lateralis (VL), and vastus medialis (VM) muscles, while ETU group mice had increased cytokine levels in the VL and VM. Total knee joint OARSI score were more significant in ETD group compared to SED and TRU groups. They were also more meaningful for the medial tibial plateau of ETD group compared to SED group. MMP-3 and cleaved Caspase-3 were higher in the ETD group than the SED and TRU group, while Adamts-5 was higher in the ETD group than the SED group. TRU group had increased PRG-4 levels compared to ETU and ETD group. ETD group had decreased total bone volume, trabecular bone volume, and cortical thickness compared to SED group.Conclusion: Excessive downhill training induced a chronic pro-inflammatory state in mice and was associated with early signs of cartilage and bone degeneration that are clinical indicators of knee OA. [ABSTRACT FROM AUTHOR]

Published
2021
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45. Evolution of nuclear structure in neutron-rich odd-Zn isotopes and isomers

Author

Wraith, C., Yang, X.F., Xie, L., Babcock, C., Bieroń, J., Billowes, J., Bissell, M.L., Blaum, K., Cheal, B., Filippin, L., Garcia Ruiz, R.F., Gins, W., Grob, L.K., Gaigalas, G., Godefroid, M., Gorges, C., Heylen, H., Honma, M., Jönsson, P., Kaufmann, S., Kowalska, M., Krämer, J., Malbrunot-Ettenauer, S., Neugart, R., Neyens, G., Nörtershäuser, W., Nowacki, F., Otsuka, T., Papuga, J., Sánchez, R., Tsunoda, Y., and Yordanov, D.T.

Published
2017
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46. Validation of Brix refractometers and a hydrometer for measuring the quality of caprine colostrum.

Author

Zobel, G., Rodriguez-Sanchez, R., Hea, S.Y., Weatherall, A., and Sargent, R.

Subjects
*REFRACTOMETERS, *SPECIFIC gravity, *STANDARDS, *GOATS, *IMMUNOGLOBULIN G, *THRESHOLD (Perception)
Abstract

On-farm assessment of caprine colostrum quality is important for goat farmers; the ability to quickly recognize whether colostrum is suitable to feed to kids helps achieve successful passive transfer of immunity. The study compared the use of optical and digital Brix refractometers and a hydrometer against the international gold standard radial immunodiffusion (RID), using both fresh and frozen samples. A locally available ELISA methodology was included for comparison. A total of 300 samples were collected from 2 farms (farm 1: n = 157, collected by research staff within 24 h of parturition; farm 2: n = 143, collected by the farmer within 12 h of parturition). Farm 1 provided doe age for a subset of samples (n = 86). Samples were tested fresh and then frozen for shipment and repeated testing. Specific gravity was measured using a hydrometer in a subset of samples (n = 22) from farm 2. Because no gold standard thresholds are currently available for caprine colostrum, RID-derived values of 30, 40, and 50 g/L IgG were used as potential "good quality" thresholds. Pearson (ρ) and Lin's concordance correlation coefficients (CCC) were calculated for comparison of methods. Optimum thresholds were established maximizing the Youden index and minimizing the "distance closest to the top left corner" of the receiver operator characteristic curves. Brix values were correlated with RID (optical Brix, fresh: ρ = 0.73; digital Brix, fresh: ρ = 0.71; digital Brix, frozen: ρ = 0.76) and with each other (range: ρ = 0.93 to 0.99; CCC = 0.91 to 0.99). Specific gravity measured by the hydrometer yielded a strong relationship with RID (ρ = 0.83) and with Brix values (range: ρ = 0.88 to 0.90). The ELISA method was not correlated with Brix methods (range: ρ = 0.02 to 0.09) or RID (ρ = 0.20). Depending on the colostrum IgG threshold, the hydrometer yielded high Youden indices (range: 0.78 to 0.93) and low distance closest to the top left corner criteria (0 to 0.05) at a threshold of 1.047 specific gravity. For all RID IgG thresholds, the best Brix threshold (regardless of type or whether the sample was fresh or frozen) was 18 or 19%, with the highest Youden indices (range: 0.47 to 0.61) and lowest distance to the top left corner criteria (range: 0.09 to 0.16); however, we recommend 19%, because this reduces the potential of feeding poor-quality colostrum. The ELISA method was the poorest predictor of colostrum concentration. Age was not found to affect colostrum quality; however, the sample size of this subset was small. Hydrometers are inexpensive and easy to use, whereas Brix methods use only a small amount of colostrum; we suggest that either method could be used on-farm. [ABSTRACT FROM AUTHOR]

Published
2020
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47. Quadrupole moments of odd-A 53−63Mn: Onset of collectivity towards N = 40

Author

Babcock, C., Heylen, H., Bissell, M.L., Blaum, K., Campbell, P., Cheal, B., Fedorov, D., Garcia Ruiz, R.F., Geithner, W., Gins, W., Day Goodacre, T., Grob, L.K., Kowalska, M., Lenzi, S.M., Maass, B., Malbrunot-Ettenauer, S., Marsh, B., Neugart, R., Neyens, G., Nörtershäuser, W., Otsuka, T., Rossel, R., Rothe, S., Sánchez, R., Tsunoda, Y., Wraith, C., Xie, L., and Yang, X.F.

Published
2016
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49. Suppressive antibiotic therapy in prosthetic joint infections: a multicentre cohort study.

Author

Escudero-Sanchez, R., Senneville, E., Digumber, M., Soriano, A., del Toro, M.D., Bahamonde, A., del Pozo, J.L., Guio, L., Murillo, O., Rico, A., García-País, M.J., Rodríguez-Pardo, D., Iribarren, J.A., Fernández, M., Benito, N., Fresco, G., Muriel, A., Ariza, J., and Cobo, J.

Subjects
*ARTIFICIAL joints, *JOINT infections, *COHORT analysis, *ARM, *TETRACYCLINES, *ANTIBIOTICS
Abstract

The aim was to describe the effectiveness of suppressive antibiotic treatment (SAT) in routine clinical practice when used in situations in which removal of a prosthetic implant is considered essential for the eradication of an infection, and it cannot be performed. This was a descriptive retrospective and multicentre cohort study of prosthetic joint infection (PJI) cases managed with SAT. SAT was considered to have failed if a fistula appeared or persisted, if debridement was necessary, if the prosthesis was removed due to persistence of the infection or if uncontrolled symptoms were present. In total, 302 patients were analysed. Two hundred and three of these patients (67.2%) received monotherapy. The most commonly used drugs were tetracyclines (39.7% of patients) (120/302) and cotrimoxazole (35.4% of patients) (107/302). SAT was considered successful in 58.6% (177/302) of the patients (median time administered, 36.5 months; IQR 20.75–59.25). Infection was controlled in 50% of patients at 5 years according to Kaplan–Meier analysis. Resistance development was documented in 15 of 65 (23.1%) of the microbiologically documented cases. SAT failure was associated with age <70 years (sub-hazard ratio (SHR) 1.61, 95% CI 1.1–2.33), aetiology other than Gram-positive cocci (SHR 1.56, 95% CI 1.09–2.27) and location of the prosthesis in the upper limb (SHR 2.4, 95% CI 1.5–3.84). SAT suspension was necessary due to adverse effects in 17 of 302 patients (5.6%). SAT offers acceptable results for patients with PJI when surgical treatment is not performed or when it fails to eradicate the infection. [ABSTRACT FROM AUTHOR]

Published
2020
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50. Effects of dietary free fatty-acid content and saturation degree on lipid-class composition and fatty-acid digestibility along the gastrointestinal tract in broiler starter chickens.

Author

Rodriguez-Sanchez, R, Tres, A, Sala, R, Garcés-Narro, C, Guardiola, F, Gasa, J, and Barroeta, A.C.

Subjects
*GASTROINTESTINAL system, *BROILER chickens, *SOY oil, *FREE fatty acids, *WHITE matter (Nerve tissue), *DIETARY fats, *PALM oil
Abstract

The aim of the present study is to assess the effect of the dietary free fatty acid (FFA) content and dietary fat saturation degree on the fatty-acid (FA) digestibility and lipid-class content along the gastrointestinal tract and excreta in broiler chickens. The 8 experimental diets resulted from replacing crude soybean oil with soybean acid oil from chemical refining, or crude palm oil with palm FA distillate from physical refining. Thus, there were 4 soybean and 4 palm diets with 6% added fat varying in their FFA% (5, 15, 35, and 50%). Samples of digestive content (gizzard, duodenum, jejunum, and ileum) and excreta were collected at 14 D for the determination of the FA digestibility and lipid-class content. The total FA digestibility coefficients reported for the chickens fed S diets in the jejunum, ileum, and excreta were higher than for those fed P diets (P ≤ 0.02). The general greater digestibility of the unsaturated diets was mainly explained by a higher contribution of the ileum to the absorption of saturated FA. The dietary FFA content mainly affected the FA absorption process. The diets with 50% FFA presented lower saturated FA digestibility coefficients in the jejunum and ileum (P ≤ 0.03), and higher content of FFA in the ileum and excreta (P ≤ 0.014), in comparison to the diets with 5% FFA. The 15% FFA diets were not different from the 5% FFA diets, regarding the saturated FA digestibility in the jejunum and excreta, and the FFA content in the ileum and excreta. It was concluded that unsaturated diets with moderate content of dietary FFA (up to 15%) could be used in broiler-chicken starter diets, as they led to similar FA absorption and performance results to the diets with the lowest dietary FFA content. From the present study, it has also been concluded that dietary saturated FA content has a greater impact on FA absorption than the dietary FFA content has. [ABSTRACT FROM AUTHOR]

Published
2019
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